Search Results - "Marincola, F. M."

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN by Cai, L-M, Lyu, X-M, Luo, W-R, Cui, X-F, Ye, Y-F, Yuan, C-C, Peng, Q-X, Wu, D-H, Liu, T-F, Wang, E, Marincola, F-M, Yao, K-T, Fang, W-Y, Cai, H-B, Li, X

“…The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and metastasis. Although multiple cellular miRNAs have been identified to regulate…”
Get full text

Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015 by Galon, J, Fox, B A, Bifulco, C B, Masucci, G, Rau, T, Botti, G, Marincola, F M, Ciliberto, G, Pages, F, Ascierto, P A, Capone, M

“…The fifth "Melanoma Bridge Meeting" took place in Naples, December 1-5th, 2015. The main topics discussed at this meeting were: Molecular and Immuno advances,…”
Get full text

CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2 by Bedognetti, D, Spivey, T L, Zhao, Y, Uccellini, L, Tomei, S, Dudley, M E, Ascierto, M L, De Giorgi, V, Liu, Q, Delogu, L G, Sommariva, M, Sertoli, M R, Simon, R, Wang, E, Rosenberg, S A, Marincola, F M

“…Background: Adoptive therapy with tumour-infiltrating lymphocytes (TILs) induces durable complete responses (CR) in ∼20% of patients with metastatic melanoma…”
Get full text

Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells by Sastry, K S R, Al-Muftah, M A, Li, Pu, Al-Kowari, M K, Wang, E, Ismail Chouchane, A, Kizhakayil, D, Kulik, G, Marincola, F M, Haoudi, A, Chouchane, L

“…Emerging evidence suggests that the resistance of cancer stem cells (CSC) to many conventional therapies is one of the major limiting factors of cancer therapy…”
Get full text

Consistent Cytotoxic-T-Lymphocyte Targeting of Immunodominant Regions in Human Immunodeficiency Virus across Multiple Ethnicities by FRAHM, Nicole, KORBER, B. T, SENGUPTA, D, PIECHOCKA-TROCHA, A, SIMONIS, T, MARINCOLA, F. M, WURCEL, A. G, STONE, D. R, RUSSELL, C. J, ADOLF, P, COHEN, D, ROACH, T, ADAMS, C. M, STJOHN, A, KHATRI, A, DAVIS, K, MULLINS, J, GOULDER, P. J. R, WALKER, B. D, BRANDER, C, SZINGER, J. J, DRAENERT, R, ADDO, M. M, FEENEY, M. E, YUSIM, K, SANGO, K, BROWN, N. V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes by Murtas, D, Maric, D, De Giorgi, V, Reinboth, J, Worschech, A, Fetsch, P, Filie, A, Ascierto, M L, Bedognetti, D, Liu, Q, Uccellini, L, Chouchane, L, Wang, E, Marincola, F M, Tomei, S

“…Background: Several lines of evidence suggest a dichotomy between immune active and quiescent cancers, with the former associated with a good prognostic…”
Get full text

Cancer Immunotherapy With Peptide-Based Vaccines: What Have We Achieved? Where Are We Going? by Parmiani, Giorgio, Castelli, Chiara, Dalerba, Piero, Mortarini, Roberta, Rivoltini, Licia, Marincola, Francesco M., Anichini, Andrea

“…Many human tumor-associated antigens (TAAs) have recently been identified and molecularly characterized. When bound to major histocompatibility complex…”
Get full text

Inherited polymorphisms in the RNA-mediated interference machinery affect microRNA expression and lung cancer survival by Rotunno, M, Zhao, Y, Bergen, A W, Koshiol, J, Burdette, L, Rubagotti, M, Linnoila, R I, Marincola, F M, Bertazzi, P A, Pesatori, A C, Caporaso, N E, McShane, L M, Wang, E, Landi, M T

“…Background: MicroRNAs (miRs) have an important role in lung carcinogenesis and progression. Single-nucleotide polymorphisms (SNPs) in genes involved in miR…”
Get full text

High-fidelity mRNA amplification for gene profiling by Marincola, Francesco M, Wang, Ena, Miller, Lance D, Ohnmacht, Galen A, Liu, Edison T

“…The completion of the Human Genome Project has made possible the comprehensive analysis of gene expression, and cDNA microarrays are now being employed for…”
Get full text

Epstein-Barr virus microRNAs and lung cancer by Koshiol, J, Gulley, M L, Zhao, Y, Rubagotti, M, Marincola, F M, Rotunno, M, Tang, W, Bergen, A W, Bertazzi, P A, Roy, D, Pesatori, A C, Linnoila, I, Dittmer, D, Goldstein, A M, Caporaso, N E, McShane, L M, Wang, E, Landi, M T

“…Background: We conducted the first analysis of viral microRNAs (miRNAs) in lung cancer, with a focus on Epstein–Barr virus (EBV). Methods: We evaluated viral…”
Get full text

Advantages of mRNA amplification for microarray analysis by Feldman, A L, Costouros, N G, Wang, E, Qian, M, Marincola, F M, Alexander, H R, Libutti, S K

“…Expanding applications of cDNA microarrays such as fine needle aspiration biopsy and laser capture microdissection necessitate the ability to perform arrays…”
Get full text

Loss of Functional Beta2-Microglobulin in Metastatic Melanomas From Five Patients Receiving Immunotherapy by Restifo, Nicholas P., Marincola, Francesco M., Kawakami, Yutaka, Taubenberger, Jeff, Yannelli, John R., Rosenberg, Steven A.

“…Background: In a subset of patients with metastatic melanoma, T lymphocytes bearing the cell-surface marker CD8 (CD8+ T cells) can cause the regression of even…”
Get full text

Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens by ROSENBERG, S. A, YIFAN ZHAI, ROBERTS, B, WHITE, D. E, YANG, J. C, SCHWARTZENTRUBER, D. J, HWU, P, MARINCOLA, F. M, TOPALIAN, S. L, RESTIFO, N. P, SEIPP, C. A, EINHORN, J. H

“…The characterization of the genes encoding melanoma-associated antigens MART-1 or gp100, recognized by T cells, has opened new possibilities for the…”
Get full text

IL-10 stimulatory effects on human NK cells explored by gene profile analysis by Mocellin, S, Panelli, M, Wang, E, Rossi, C R, Pilati, P, Nitti, D, Lise, M, Marincola, F M

“…The molecular mechanisms underlying the increase of natural killer (NK) cell anticancer activity mediated by interleukin (IL)-10 have not been elucidated. The…”
Get full text

Prospective Randomized Trial of the Treatment of Patients With Metastatic Melanoma Using Chemotherapy With Cisplatin, Dacarbazine, and Tamoxifen Alone or in Combination With Interleukin-2 and Interferon Alfa-2b by ROSENBERG, S. A, YANG, J. C, SCHWARTZENTRUBER, D. J, HWU, P, MARINCOLA, F. M, TOPALIAN, S. L, SEIPP, C. A, EINHORN, J. H, WHITE, D. E, STEINBERG, S. M

“…The combination of chemotherapy with immunotherapeutic agents such as interleukin-2 and interferon alfa-2b has been reported to provide improved treatment…”
Get full text

Phase 1 study in patients with metastatic melanoma of immunization with Dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100 by PANELLI, M. C, WUNDERLICH, J, JEFFRIES, J, WANG, E, MIXON, A, ROSENBERG, S. A, MARINCOLA, F. M

“…Dendritic cells (DCs) have been shown to enhance anti-tumor immune responses in several preclinical models. Furthermore, DC-like function can be elicited from…”
Get full text

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7 by Steller, M A, Gurski, K J, Murakami, M, Daniel, R W, Shah, K V, Celis, E, Sette, A, Trimble, E L, Park, R C, Marincola, F M

“…Human papillomavirus (HPV) infection has been causally associated with cervical cancer. We tested the effectiveness of an HLA-A*0201-restricted, HPV-16 E7…”
Get full text

Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides by SALGALLER, M. L, MARINCOLA, F. M, CORMIER, J. N, ROSENBERG, S. A

“…gp1OO is a melanocytic lineage-specific antigen recognized by tumor-infiltrating lymphocytes, the adoptive transfer of which is associated with tumor…”
Get full text

Real-Time Quantitative Polymerase Chain Reaction Assessment of Immune Reactivity in Melanoma Patients After Tumor Peptide Vaccination by Kammula, Udai S., Marincola, Francesco M., Rosenberg, Steven A.

“…Background: Monitoring the immune response to epitope-specific vaccination in cancer patients is important for vaccine development. The traditional method, in…”
Get full text

Intensity of the Vaccine-Elicited Immune Response Determines Tumor Clearance by Perez-Diez, Ainhoa, Spiess, Paul J, Restifo, Nicholas P, Matzinger, Polly, Marincola, Francesco M

“…Tumor Ag-specific vaccines used for cancer immunotherapy can generate specific CD8 responses detectable in PBMCs and in tumor-infiltrating lymphocytes…”
Get full text