Search Results - "Marin, Kollef"
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Bacterial and fungal superinfections in critically ill patients with COVID-19
Published in Intensive care medicine (01-11-2020)Get full text
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Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)
Published in Intensive care medicine (01-02-2020)“…Background Antimicrobial de-escalation (ADE) is a strategy of antimicrobial stewardship, aiming at preventing the emergence of antimicrobial resistance (AMR)…”
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Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: a retrospective cohort study
Published in Critical care (London, England) (21-11-2014)“…The impact of in vitro resistance on initially appropriate antibiotic therapy (IAAT) remains unclear. We elucidated the relationship between non-IAAT and…”
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International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia
Published in The European respiratory journal (01-09-2017)“…The most recent European guidelines and task force reports on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost…”
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Targeted Fluid Minimization Following Initial Resuscitation in Septic Shock: A Pilot Study
Published in Chest (01-12-2015)“…IV fluid represents a basic therapeutic intervention for septic shock. Unfortunately, the optimal administration of IV fluid to maximize patient outcomes and…”
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Nosocomial Infection
Published in Critical care medicine (01-02-2021)“…The first 70 years of critical care can be considered a period of "industrial revolution-like" advancement in terms of progressing the understanding and care…”
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Culture-negative sepsis
Published in Current opinion in critical care (01-10-2020)“…The traditional approach to sepsis treatment utilizes broad-spectrum antibiotics. Unfortunately, a significant proportion of infected patients have…”
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Broad-Spectrum Antimicrobials and the Treatment of Serious Bacterial Infections: Getting It Right Up Front
Published in Clinical infectious diseases (15-09-2008)“…The treatment of serious bacterial infections is complicated by the fact that time to initiation of effective antimicrobial therapy is a strong predictor of…”
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Economic Impact of Ventilator-Associated Pneumonia in a Large Matched Cohort
Published in Infection control and hospital epidemiology (01-03-2012)“…Objective. To evaluate the economic impact of ventilator-associated pneumonia (VAP) on length of stay and hospital costs. Design. Retrospective matched cohort…”
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A Case-Control Study Assessing the Impact of Nonventilated Hospital-Acquired Pneumonia on Patient Outcomes
Published in Chest (01-11-2016)“…Background Nonventilated hospital-acquired pneumonia (NVHAP) is a serious nosocomial infection that is increasingly attributed to antibiotic-resistant…”
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Re-estimating annual deaths due to multidrug-resistant organism infections
Published in Infection control and hospital epidemiology (01-01-2019)“…To the Editor—Multidrug-resistant organisms (MDROs) are responsible for an increasing number of infections each year.1 An oft-cited statistic is that MDRO…”
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Time to Appropriate Antibiotic Therapy Is an Independent Determinant of Postinfection ICU and Hospital Lengths of Stay in Patients With Sepsis
Published in Critical care medicine (01-10-2015)“…OBJECTIVE:To assess the timing of appropriate antibiotic therapy as a determinant of postinfection hospital and ICU lengths of stay in patients with sepsis…”
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Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of Gram-negative nosocomial pneumonia (APEKS-NP): a randomised, double-blind, phase 3, non-inferiority trial
Published in The Lancet infectious diseases (01-02-2021)“…Nosocomial pneumonia due to multidrug-resistant Gram-negative pathogens poses an increasing challenge. We compared the efficacy and safety of cefiderocol…”
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Initial antimicrobial management of sepsis
Published in Critical care (London, England) (26-08-2021)“…Sepsis is a common consequence of infection, associated with a mortality rate > 25%. Although community-acquired sepsis is more common, hospital-acquired…”
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Is Zero Ventilator-Associated Pneumonia Achievable? Updated Practical Approaches to Ventilator-Associated Pneumonia Prevention
Published in Infectious disease clinics of North America (01-03-2024)“…Ventilator-associated pneumonia (VAP) remains a significant clinical entity with reported incidence rates of 7% to 15%. Given the considerable adverse…”
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Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus
Published in Clinical infectious diseases (01-06-2008)“…A recent increase in staphylococcal infections caused by methicillin-resistant Staphylococcus aureus (MRSA), combined with frequent, prolonged ventilatory…”
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How to use new antibiotics in the therapy of serious multidrug resistant Gram-negative infections?
Published in Current opinion in infectious diseases (01-12-2022)“…Multidrug resistant Gram-negative infections are becoming more common and pose a serious threat to both individual patients and the population as a whole…”
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Sepsis-Associated Coagulopathy Severity Predicts Hospital Mortality
Published in Critical care medicine (01-05-2018)“…OBJECTIVES:To assess whether sepsis-associated coagulopathy predicts hospital mortality. DESIGN:Retrospective cohort study. SETTING:One-thousand three-hundred…”
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Duration of Exposure to Antipseudomonal β‐Lactam Antibiotics in the Critically Ill and Development of New Resistance
Published in Pharmacotherapy (01-03-2019)“…Study Objective Minimizing the duration of broad‐spectrum antimicrobial exposure in the critically ill is a commonly used strategy aimed at preventing…”
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The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship
Published in Intensive care medicine (01-09-2017)“…Purpose To concisely describe the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of…”
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