Search Results - "Marin, Christophe"

Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes by Abounit, Saïda, Bousset, Luc, Loria, Frida, Zhu, Seng, de Chaumont, Fabrice, Pieri, Laura, Olivo-Marin, Jean-Christophe, Melki, Ronald, Zurzolo, Chiara

“…Synucleinopathies such as Parkinson's disease are characterized by the pathological deposition of misfolded α‐synuclein aggregates into inclusions throughout…”
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Statistical analysis of molecule colocalization in bioimaging by Lagache, Thibault, Sauvonnet, Nathalie, Danglot, Lydia, Olivo‐Marin, Jean‐Christophe

“…The quantitative analysis of molecule interactions in bioimaging is key for understanding the molecular orchestration of cellular processes and is generally…”
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A role for septin 2 in Drp1-mediated mitochondrial fission by Pagliuso, Alessandro, Tham, To Nam, Stevens, Julia K, Lagache, Thibault, Persson, Roger, Salles, Audrey, Olivo-Marin, Jean-Christophe, Oddos, Stéphane, Spang, Anne, Cossart, Pascale, Stavru, Fabrizia

“…Mitochondria are essential eukaryotic organelles often forming intricate networks. The overall network morphology is determined by mitochondrial fusion and…”
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Automated staining analysis in digital cytopathology and applications by Bouyssoux, Alexandre, Jarnouen, Kathleen, Lallement, Laetitia, Fezzani, Riadh, Olivo‐Marin, Jean‐Christophe

“…The progress of digital pathology in recent years has been an opportunity for the development of automated image analysis algorithms for quantitative…”
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Mapping molecular assemblies with fluorescence microscopy and object-based spatial statistics by Lagache, Thibault, Grassart, Alexandre, Dallongeville, Stéphane, Faklaris, Orestis, Sauvonnet, Nathalie, Dufour, Alexandre, Danglot, Lydia, Olivo-Marin, Jean-Christophe

“…Elucidating protein functions and molecular organisation requires to localise precisely single or aggregated molecules and analyse their spatial distributions…”
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E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow by Grimaldi, Cecilia, Schumacher, Isabel, Boquet-Pujadas, Aleix, Tarbashevich, Katsiaryna, Vos, Bart Eduard, Bandemer, Jan, Schick, Jan, Aalto, Anne, Olivo-Marin, Jean-Christophe, Betz, Timo, Raz, Erez

“…The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms responsible for focusing this…”
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Performing point-of-care molecular testing for SARS-CoV-2 with RNA extraction and isothermal amplification by Garneret, Pierre, Coz, Etienne, Martin, Elian, Manuguerra, Jean-Claude, Brient-Litzler, Elodie, Enouf, Vincent, González Obando, Daniel Felipe, Olivo-Marin, Jean-Christophe, Monti, Fabrice, van der Werf, Sylvie, Vanhomwegen, Jessica, Tabeling, Patrick

“…To respond to the urgent need for COVID-19 testing, countries perform nucleic acid amplification tests (NAAT) for the detection of SARS-CoV-2 in centralized…”
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Live Cells Imaging and Comparative Phosphoproteomics Uncover Proteins from the Mechanobiome in Entamoeba histolytica by Jhingan, Gagan Deep, Manich, Maria, Olivo-Marin, Jean-Christophe, Guillen, Nancy

“…is a protozoan parasite and the causative agent of amoebiasis in humans. This amoeba invades human tissues by taking advantage of its actin-rich cytoskeleton…”
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Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status by Momboisse, Fanny, Nardi, Giacomo, Colin, Philippe, Hery, Melanie, Cordeiro, Nelia, Blachier, Simon, Schwartz, Olivier, Arenzana-Seisdedos, Fernando, Sauvonnet, Nathalie, Olivo-Marin, Jean-Christophe, Lagane, Bernard, Lagache, Thibault, Brelot, Anne

“…G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states. However, how these states impact GPCRs…”
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Automatic monitoring of neural activity with single-cell resolution in behaving Hydra by Hanson, Alison, Reme, Raphael, Telerman, Noah, Yamamoto, Wataru, Olivo-Marin, Jean-Christophe, Lagache, Thibault, Yuste, Rafael

“…The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, we report coming one step closer…”
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Computerized video analysis of social interactions in mice by de Chaumont, Fabrice, Coura, Renata Dos-Santos, Serreau, Pierre, Cressant, Arnaud, Chabout, Jonathan, Granon, Sylvie, Olivo-Marin, Jean-Christophe

“…We describe software, MiceProfiler, for automatic tracking of two interacting mice and analysis of their social interactions without the need of animal…”
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Intraflagellar transport proteins cycle between the flagellum and its base by Buisson, Johanna, Chenouard, Nicolas, Lagache, Thibault, Blisnick, Thierry, Olivo-Marin, Jean-Christophe, Bastin, Philippe

“…Intraflagellar transport (IFT) is necessary for the construction of cilia and flagella. IFT proteins are concentrated at the base of the flagellum but little…”
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Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth by Ragni, Chiara V., Diguet, Nicolas, Le Garrec, Jean-François, Novotova, Marta, Resende, Tatiana P., Pop, Sorin, Charon, Nicolas, Guillemot, Laurent, Kitasato, Lisa, Badouel, Caroline, Dufour, Alexandre, Olivo-Marin, Jean-Christophe, Trouvé, Alain, McNeill, Helen, Meilhac, Sigolène M

“…Although in flies the atypical cadherin Fat is an upstream regulator of Hippo signalling, the closest mammalian homologue, Fat4, has been shown to regulate…”
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Cytokine receptor cluster size impacts its endocytosis and signaling by Salavessa, Laura, Lagache, Thibault, Malardé, Valérie, Grassart, Alexandre, Olivo-Marin, Jean-Christophe, Canette, Alexis, Trichet, Michael, Sansonetti, Philippe J., Sauvonnet, Nathalie

“…The interleukin-2 receptor (IL-2R) is a cytokine receptor essential for immunity that transduces proliferative signals regulated by its uptake and degradation…”
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Fluid dynamics during bleb formation in migrating cells in vivo by Goudarzi, Mohammad, Boquet-Pujadas, Aleix, Olivo-Marin, Jean-Christophe, Raz, Erez

“…Blebs are cellular protrusions observed in migrating cells and in cells undergoing spreading, cytokinesis, and apoptosis. Here we investigate the flow of…”
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ActA promotes Listeria monocytogenes aggregation, intestinal colonization and carriage by Travier, Laetitia, Guadagnini, Stéphanie, Gouin, Edith, Dufour, Alexandre, Chenal-Francisque, Viviane, Cossart, Pascale, Olivo-Marin, Jean-Christophe, Ghigo, Jean-Marc, Disson, Olivier, Lecuit, Marc

“…Listeria monocytogenes (Lm) is a ubiquitous bacterium able to survive and thrive within the environment and readily colonizes a wide range of substrates, often…”
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Analysis of the spatial organization of molecules with robust statistics by Lagache, Thibault, Lang, Gabriel, Sauvonnet, Nathalie, Olivo-Marin, Jean-Christophe

“…One major question in molecular biology is whether the spatial distribution of observed molecules is random or organized in clusters. Indeed, this analysis…”
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Insights into amebiasis using a human 3D‐intestinal model by Aguilar‐Rojas, Arturo, Castellanos‐Castro, Silvia, Matondo, Mariette, Gianetto, Quentin Giai, Varet, Hugo, Sismeiro, Odile, Legendre, Rachel, Fernandes, Julien, Hardy, David, Coppée, Jean‐Yves, Olivo‐Marin, Jean‐Christophe, Guillen, Nancy

“…Entamoeba histolytica is the causative agent of amebiasis, an infectious disease targeting the intestine and the liver in humans. Two types of intestinal…”
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The motility of Entamoeba histolytica : finding ways to understand intestinal amoebiasis by Aguilar-Rojas, Arturo, Olivo-Marin, Jean-Christophe, Guillen, Nancy

“…Highlights • Motility in E. histolytica is associated with rapid changes in cell morphology. • Migration by E. histolytica varies according to the…”
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Real-time analysis of the behaviour of groups of mice via a depth-sensing camera and machine learning by de Chaumont, Fabrice, Ey, Elodie, Torquet, Nicolas, Lagache, Thibault, Dallongeville, Stéphane, Imbert, Albane, Legou, Thierry, Le Sourd, Anne-Marie, Faure, Philippe, Bourgeron, Thomas, Olivo-Marin, Jean-Christophe

“…Preclinical studies of psychiatric disorders use animal models to investigate the impact of environmental factors or genetic mutations on complex traits such…”
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