Search Results - "Mariko Hashimoto"

Stimulus salience determines defensive behaviors elicited by aversively conditioned serial compound auditory stimuli by Hersman, Sarah, Allen, David, Hashimoto, Mariko, Brito, Salvador Ignacio, Anthony, Todd E

“…Assessing the imminence of threatening events using environmental cues enables proactive engagement of appropriate avoidance responses. The neural processes…”
Get full text

Lateral septum modulates cortical state to tune responsivity to threat stimuli by Hashimoto, Mariko, Brito, Salvador Ignacio, Venner, Anne, Pasqualini, Amanda Loren, Yang, Tracy Lulu, Allen, David, Stankowicz, Sarah J., Fuller, Patrick Michael, Anthony, Todd Erryl

Get full text

Utility of ultrasonography for predicting indications for tolvaptan in patients with autosomal dominant polycystic kidney disease by Iijima, Hiroko, Tada, Toshifumi, Hashimoto, Mariko, Nishimura, Takashi, Kiriki, Masato, Higashiura, Akiko, Iwasaki, Aya, Honda, Michino, Nagasawa, Yasuyuki, Yamakado, Koichiro

“…Purpose Tolvaptan is the first approved treatment for autosomal dominant polycystic kidney disease (ADPKD) that targets a mechanism directly contributing to…”
Get full text

Reduced Temporal Activation During a Verbal Fluency Task is Associated with Poor Motor Speed in Patients with Major Depressive Disorder by Kiriyama, Tomohiko, Tanemura, Rumi, Nakamura, Yoshihiro, Takemoto, Chiaki, Hashimoto, Mariko, Utsumi, Hirohiko

“…Objective Substantial research has revealed cognitive function impairments in patients with major depressive disorder (MDD). However, the relationship between…”
Get full text

Prepeak of trolox caused by theophylline and its application to the determination of theophylline in rat plasma by Kotani, Akira, Hashimoto, Mariko, Kotani, Tomoko, Kusu, Fumiyo

“…A novel electrochemical detection coupled with high-performance liquid chromatography (HPLC) was developed for determining theophylline in plasma samples. On a…”
Get full text

Reduced Temporal Activation During a Verbal Fluency Task is Associated with Poor Motor Speed in Patients with Major Depressive Disorder by Tomohiko Kiriyama, Rumi Tanemura, Yoshihiro Nakamura, Chiaki Takemoto, Mariko Hashimoto, Hirohiko Utsumi

Get full text

Trimeric purine nucleoside phosphorylase: Exploring postulated one-third-of-the-sites binding in the transition state by Wielgus-Kutrowska, Beata, Breer, Katarzyna, Hashimoto, Mariko, Hikishima, Sadao, Yokomatsu, Tsutomu, Narczyk, Marta, Dyzma, Alicja, Girstun, Agnieszka, Staroń, Krzysztof, Bzowska, Agnieszka

“…Transition-state analogue inhibitors, immucillins, were reported to bind to trimeric purine nucleoside phosphorylase (PNP) with the stoichiometry of one…”
Get full text

9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase by Breer, Katarzyna, Glavaš-Obrovac, Ljubica, Suver, Mirjana, Hikishima, Sadao, Hashimoto, Mariko, Yokomatsu, Tsutomu, Wielgus-Kutrowska, Beata, Magnowska, Lucyna, Bzowska, Agnieszka

“…Genetic deficiency of purine nucleoside phosphorylase (PNP; EC 2.4.2.1) activity leads to a severe selective disorder of T-cell function. Therefore, potent…”
Get full text

Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors by Hosoda, Shinnosuke, Matsuda, Daisuke, Tomoda, Hiroshi, Hashimoto, Mariko, Aoyama, Hiroshi, Hashimoto, Yuichi

“…HMG-CoA reductase inhibitors with a 3,3-diphenylpentane skeleton were prepared. Based on our hypothesis that the 3,3-diphenylpentane (DPP) skeleton is useful…”
Get full text

Discovery of diphenylmethane analogs as anti-bovine diarrhea viral agents by Hosoda, Shinnosuke, Aoyama, Hiroshi, Goto, Yukinori, Salim, Mohammed T.A., Okamoto, Mika, Hashimoto, Mariko, Baba, Masanori, Hashimoto, Yuichi

“…1,1-Diphenylcyclobutane analog and diethyldiphenylsilane analogs have been identified as superior lead compounds with potent anti-bovine viral diarrhea…”
Get full text

Immunohistochemical Localization of Syndecan‐1 in the Dental Follicle of Postnatal Mouse Teeth by Shibata, Shunichi, Dias, Rubia A., Hashimoto‐Uoshima, Mariko, Abe, Tatsuhiko, Yanagishita, Masaki

“…Background: Syndecans are cell surface heparan sulfate proteoglycans that modulate the action of growth factors and extracellular matrix components. Syndecan‐1…”
Get full text

Syndecan‐1 Expression During the Formation of Junctional Epithelium by Dias, Rubia A., Shibata, Shunichi, Hashimoto‐Uoshima, Mariko, Podyma‐Inoue, Katarzyna A., Ishikawa, Isao, Yanagishita, Masaki

“…Background: Syndecans are cell surface heparan sulfate proteoglycans (PG) which can bind to and modulate the action of growth factors and extracellular matrix…”
Get full text

Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves by Iguchi, Tomoki, Kuroda, Minpei, Akiyama, Nanami, Hashimoto, Mariko, Mimaki, Yoshihiro

“…Systematic phytochemical investigation of the bark and leaves of was independently conducted. A new cyclic diarylheptanoid glucoside ( ), five diarylheptanoids…”
Get full text

Modeling and control of a class of urban air mobility tiltrotor aircraft by Su, Weihua, Qu, Shen, Zhu, Guoming, Swei, Sean Shan-Min, Hashimoto, Mariko, Zeng, Tao

“…This paper aims at developing a control-centric analytical formulation for aeromechanics and flight dynamics of urban air mobility (UAM) vehicles. Such…”
Get full text

Metabolic dysfunction‐associated steatotic liver disease criteria may underestimate the number of lean female nonalcoholic fatty liver disease patients with significant liver fibrosis by Kobayashi, Natsuko, Tada, Toshifumi, Nishimura, Takashi, Matono, Tomomitsu, Yuri, Yukihisa, Takashima, Tomoyuki, Aizawa, Nobuhiro, Ikeda, Naoto, Fukunishi, Shinya, Hashimoto, Mariko, Ohyanagi, Mitsumasa, Enomoto, Hirayuki, Iijima, Hiroko

“…Aim It remains unclear whether the newly defined concept of metabolic dysfunction‐associated steatotic liver disease (MASLD) appropriately includes patients…”
Get full text

Lateral septum modulates cortical state to tune responsivity to threat stimuli by Hashimoto, Mariko, Brito, Salvador Ignacio, Venner, Anne, Pasqualini, Amanda Loren, Yang, Tracy Lulu, Allen, David, Fuller, Patrick Michael, Anthony, Todd Erryl

“…Sudden unexpected environmental changes capture attention and, when perceived as potentially dangerous, evoke defensive behavioral states. Perturbations of the…”
Get full text

Final Results from a Non-Interventional Safety and Efficacy Study of a VWF/FVIII Concentrate (wilate®) in Patients with Von Willebrand Disease by Yaish, Hassan M., Cruz, Maria Sol, Decker, Kay, Zetterberg, Eva M.K., Werner, Sylvia, Hashimoto, Mariko, Knaub, Sigurd, Rodgers, George M.

“…Introduction: Post-marketing studies provide important insight into the consistency of data from clinical studies and routine clinical use. This…”
Get full text

Synthesis and Structural Comparison of TpiPr2Rh[cis-1,2-bis(diphenylphosphino)ethene]:  Factors Determining Hapticity (κ2 vs κ3) of the TpiPr2 Ligand in TpiPr2Rh(diphosphine) Complexes by AKITA, Munetaka, HASHIMOTO, Mariko, HIKICHI, Shiro, MORO-OKA, Yoshihiko

Get full text

A New Ultrasonographic “Fluttering Sign” for Hepatic Hemangioma by Kobayashi, Natsuko, Iijima, Hiroko, Tada, Toshifumi, Shibata, Yoko, Nishimura, Takashi, Kumada, Takashi, Hashimoto, Mariko, Higashiura, Akiko, Yoshida, Masahiro, Nishimura, Junko, Aizawa, Nobuhiro, Ikeda, Naoto, Takashima, Tomoyuki, Takata, Ryo, Nishikawa, Hiroki, Iwata, Yoshinori, Enomoto, Hirayuki, Hirota, Seiichi, Hatano, Etsuro

“…The aim of the study described here was to clarify the diagnostic value of the fluttering sign, a new sign that characterizes hepatic hemangiomas in gray-scale…”
Get full text

Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs by Hikishima, Sadao, Hashimoto, Mariko, Magnowska, Lucyna, Bzowska, Agnieszka, Yokomatsu, Tsutomu

“…9-(5′,5′-Difluoro-5′-phosphonopentyl)-9-deazaguanine ( DFPP-DG) was designed as a multi-substrate analogue inhibitor against purine nucleoside phosphorylase…”
Get full text