Search Results - "Marians, K. J."

Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions by HONG PENG, MARIANS, K. J

“…DNA sequence analysis of Escherichia coli parC and parE, encoding the subunits of topoisomerase IV (Topo IV) (Kato, J.-I., Suzuki, H., and Ikeda, H. (1992) J…”
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Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork by Tougu, K, Peng, H, Marians, K J

“…Primase plays a key role in governing the sequence of events required on the lagging strand during a cycle of Okazaki fragment synthesis. To begin to probe the…”
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Prokaryotic DNA Replication by Marians, Kenneth J

“…Biochemical and genetic analyses have revealed that the action of at least 30 proteins is required to replicate the chromosome of Escherichia coli. Much of the…”
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Decatenation Activity of Topoisomerase IV During oriC and pBR322 DNA Replication in vitro by Peng, Hong, Marians, Kenneth J.

“…Topoisomerase IV (Topo IV), encoded by parC and parE, is required for partition of the daughter chromosomes in Escherichia coli. This enzyme is likely…”
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Two Distinct Triggers for Cycling of the Lagging Strand Polymerase at the Replication Fork by Li, Xiaojun, Marians, Kenneth J.

“…There are two modes of DNA synthesis at a replication fork. The leading strand is synthesized in a continuous fashion in lengths that in Escherichia coli can…”
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Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response by NURSE, P, ZAVITZ, K. H, MARIANS, K. J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Crawling and Wiggling on DNA: Structural Insights to the Mechanism of DNA Unwinding by Helicases by Marians, Kenneth J

“…Crystal structures have recently been solved of the monomeric DNA helicase PcrA bound to forked DNA, and of the hexameric helicase domain of the bacteriophage…”
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Identification of a potent decatenating enzyme from Escherichia coli by DiGate, R J, Marians, K J

“…A topoisomerase has been purified from extracts of a topoisomerase I-deficient strain of Escherichia coli based solely on its ability to segregate pBR322 DNA…”
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The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate by Mok, M, Marians, KJ

“…A DNA replication system was developed that could generate rolling-circle DNA molecules in vitro in amounts that permitted kinetic analyses of the movement of…”
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Decatenating activity of Escherichia coli DNA gyrase and topoisomerases I and III during oriC and pBR322 DNA replication in vitro by HIASA, H, DIGATE, R. J, MARIANS, K. J

“…oriC and pBR322 DNA replication, reconstituted with purified replication proteins, has been used to study the functional activities of Escherichia coli…”
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Topoisomerase IV can support oriC DNA replication in vitro by HIASA, H, MARIANS, K. J

“…Escherichia coli has two type II topoisomerases, DNA gyrase and topoisomerase IV (Topo IV). Topo IV is required for the decatenation of the linked daughter…”
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Topoisomerase III, but not topoisomerase I, can support nascent chain elongation during theta-type DNA replication by Hiasa, H, Marians, K J

“…Topoisomerase III, but not topoisomerase I, could, in the absence of DNA gyrase, support bidirectional DNA replication in an oriC plasmid DNA replication…”
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Molecular cloning and DNA sequence analysis of Escherichia coli topB, the gene encoding topoisomerase III by DiGate, R J, Marians, K J

“…Escherichia coli contains two type 1 topoisomerases, topoisomerase I and III. Although topoisomerase III can be purified as a potent decatenase, its role in…”
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Escherichia Coli Tus Protein Acts to Arrest the Progression of DNA Replication Forks in vitro by Hill, Thomas M., Marians, Kenneth J.

“…A polar DNA replication barrier is formed when the DNA-binding protein Tus forms a complex with any of the four 23-base-pair terminator (ter) sites found in…”
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Escherichia coli Replication Factor Y, a Component of the Primosome, Can Act as a DNA Helicase by Lee, Myung Soo, Marians, K. J.

“…The primosome is a mobile multienzyme DNA replication-priming complex that requires seven Escherichia coli proteins for assembly (the products of the dnaB,…”
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Differential inhibition of the DNA translocation and DNA unwinding activities of DNA helicases by the Escherichia coli Tus protein by HIASA, H, MARIANS, K. J

“…Binding of the Escherichia coli Tus protein to its cognate nonpalindromic binding site on duplex DNA (a Ter sequence) is sufficient to arrest the progression…”
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The Disposition of Nascent Strands at Stalled Replication Forks Dictates the Pathway of Replisome Loading during Restart by Heller, Ryan C., Marians, Kenneth J.

“…Rescue of arrested and collapsed replication forks is essential for maintenance of genomic integrity. One system for origin of replication-independent loading…”
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Primase couples leading- and lagging-strand DNA synthesis from oriC by HIASA, H, MARIANS, K. J

“…Coupling of leading- and lagging-strand DNA synthesis at replication forks formed at Escherichia coli oriC has been studied in vitro using a replication system…”
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The importance of repairing stalled replication forks by Goodman, Myron F, Cox, Michael M, Kreuzer, Kenneth N, Sherratt, David J, Sandler, Steven J, Marians, Kenneth J

“…The bacterial SOS response to unusual levels of DNA damage has been recognized and studied for several decades. Pathways for re-establishing inactivated…”
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ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes by Zavitz, K H, Marians, K J

“…The PriA replication protein of Escherichia coli (formerly replication factor Y or protein n') is multifunctional. It is a site-specific, single-stranded…”
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