Search Results - "Mariage, Aline"
-
1
Exploring natural biodiversity to expand access to microbial terpene synthesis
Published in Microbial cell factories (01-02-2019)“…Terpenes are industrially relevant natural compounds the biosynthesis of which relies on two well-established-mevalonic acid (MVA) and methyl erythritol…”
Get full text
Journal Article -
2
Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis
Published in Nature chemical biology (01-08-2017)“…MetA and MetX are phylogenetically unrelated families of acyl- L -homoserine transferases. Experimental assignation of function and structural modeling of…”
Get full text
Journal Article -
3
Purification and Characterization of Nitphym, a Robust Thermostable Nitrilase From Paraburkholderia phymatum
Published in Frontiers in bioengineering and biotechnology (01-07-2021)“…Despite the success of some nitrilases in industrial applications, there is a constant demand to broaden the catalog of these hydrolases, especially robust…”
Get full text
Journal Article -
4
Simplified in Vitro and in Vivo Bioaccess to Prenylated Compounds
Published in ACS omega (30-04-2019)“…All naturally produced terpenes are derived from two universal C5 diphosphate precursors, dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP)…”
Get full text
Journal Article -
5
Discovery and Enzymatic Screening of Genome-Mined Microbial Levanases to Produce Second-Generation β‑(2,6)-Fructooligosaccharides: Catalytic Properties
Published in ACS chemical biology (17-03-2023)“…Evidence suggests that β-(2,6)-levan-type fructooligosaccharides (FOSs) possess higher prebiotic potential and selectivity than their β-(2,1)-inulin-type…”
Get full text
Journal Article -
6
A family of native amine dehydrogenases for the asymmetric reductive amination of ketones
Published in Nature catalysis (01-04-2019)“…The asymmetric reductive amination of ketones enables the one-step synthesis of chiral amines from readily available starting materials. Here we report the…”
Get full text
Journal Article -
7
Synthesis of Branched‐Chain Sugars with a DHAP‐Dependent Aldolase: Ketones are Electrophile Substrates of Rhamnulose‐1‐phosphate Aldolases
Published in Angewandte Chemie International Edition (04-05-2018)“…Dihydroxyacetone phosphate (DHAP)‐dependent rhamnulose aldolases display an unprecedented versatility for ketones as electrophile substrates. We selected and…”
Get full text
Journal Article -
8
Revealing the hidden functional diversity of an enzyme family
Published in Nature chemical biology (01-01-2014)“…Enzyme annotations often suffer from incomplete functional information for homologous sequences. Extrapolation from one characterized enzyme to multiple…”
Get full text
Journal Article -
9
Biocatalytic Approaches towards the Synthesis of Chiral Amino Alcohols from Lysine: Cascade Reactions Combining alpha‐Keto Acid Oxygenase Hydroxylation with Pyridoxal Phosphate‐ Dependent Decarboxylation
Published in Advanced synthesis & catalysis (02-05-2017)“…Amino alcohols are a very common structural motif in natural and synthetic molecules. Starting from l‐lysine and hydroxy‐l‐lysine, a straightforward…”
Get full text
Journal Article -
10
Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis
Published in Advanced synthesis & catalysis (17-06-2013)“…A high‐throughput screening of candidate nitrilases against 25 structurally diverse substrates allowed us to create a wide collection of 125 experimentally…”
Get full text
Journal Article -
11
Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars
Published in Applied microbiology and biotechnology (01-07-2018)“…Most of the “repressor, open reading frame, kinase” (ROK) proteins already characterized so far, and exhibiting a kinase activity, take restrictedly d -glucose…”
Get full text
Journal Article -
12
Synthesis of Mono- and Dihydroxylated Amino Acids with New α-Ketoglutarate-Dependent Dioxygenases: Biocatalytic Oxidation of CH Bonds
Published in ChemCatChem (01-10-2014)“…Iron(II)/α‐ketoacid‐dependent oxygenases (αKAOs) are enzymes that mainly catalyse hydroxylation reaction. By using a genomic approach combining sequence…”
Get full text
Journal Article -
13
Purification and Characterization of Nit phym , a Robust Thermostable Nitrilase From Paraburkholderia phymatum
Published in Frontiers in bioengineering and biotechnology (01-01-2021)Get full text
Journal Article -
14
Erratum: Corrigendum: Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis
Published in Nature chemical biology (01-10-2017)Get full text
Journal Article -
15
Correction: Corrigendum: Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis
Published in Nature chemical biology (01-10-2017)“…Nat. Chem. Biol. 13, 858–866 (2017); published online 5 June 2017; corrected after print 10 July 2017 In the version of this article initially published, a…”
Get full text
Journal Article -
16
Corrigendum: Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis
Published in Nature chemical biology (19-09-2017)Get full text
Journal Article -
17
Genome Mining for Innovative Biocatalysts: New Dihydroxyacetone Aldolases for the Chemist's Toolbox
Published in ChemCatChem (15-06-2015)“…Stereoselective carboligating enzymes were discovered by a genome mining approach to extend the biocatalysis toolbox. Seven hundred enzymes were selected by…”
Get full text
Journal Article -
18
Large α-aminonitrilase activity screening of nitrilase superfamily members: Access to conversion and enantiospecificity by LC–MS
Published in Journal of molecular catalysis. B, Enzymatic (01-09-2014)“…•We performed a large nitrilase activity screening on α-aminonitriles.•The enzyme collection covers the whole biodiversity of the nitrilase superfamily.•An…”
Get full text
Journal Article -
19
Synthesis of Mono- and Dihydroxylated Amino Acids with New [alpha]-Ketoglutarate-Dependent Dioxygenases: Biocatalytic Oxidation of CH Bonds
Published in ChemCatChem (01-10-2014)“…Iron(II)/[alpha]-ketoacid-dependent oxygenases ([alpha]KAOs) are enzymes that mainly catalyse hydroxylation reaction. By using a genomic approach combining…”
Get full text
Journal Article -
20
Synthesis of Branched‐Chain Sugars with a DHAP‐Dependent Aldolase: Ketones are Electrophile Substrates of Rhamnulose‐1‐phosphate Aldolases
Published in Angewandte Chemie (04-05-2018)“…Dihydroxyacetone phosphate (DHAP)‐dependent rhamnulose aldolases display an unprecedented versatility for ketones as electrophile substrates. We selected and…”
Get full text
Journal Article