Search Results - "Maria de Lima Alves"

Thiazolidinedione and thiazole derivatives potentiate norfloxacin activity against NorA efflux pump over expression in Staphylococcus aureus 1199B strains by Pereira, Pedro Silvino, Lima, Maria do Carmo Alves de, Neto, Pedro Paulo Marcelino, Oliveira-Tintino, Cícera Datiane de Morais, Tintino, Saulo Relison, Menezes, Irwin Rose de Alencar, de Oliveira, Jamerson Ferreira, Marchand, Pascal, Coutinho, Henrique Douglas Melo, Rodrigues, Maria do Desterro, da Silva, Teresinha Gonçalves

“…[Display omitted] Thiazol and thiazolidinedione derivatives are known in the literature for presenting several biological activities, such as anti-diabetic,…”
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Anticancer properties of thiophene derivatives in breast cancer MCF-7 cells by Dos Santos, Flaviana Alves, Pereira, Michelly Cristiny, de Oliveira, Tiago Bento, Mendonça Junior, Francisco Jaime Bezerra, de Lima, Maria do Carmo Alves, Pitta, Marina Galdino da Rocha, Pitta, Ivan da Rocha, de Melo Rêgo, Moacyr Jesus Barreto, da Rocha Pitta, Maira Galdino

“…Substitutions in thiophene structure give rise to new derivatives with different biological and pharmacological activities. The present study investigated the…”
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LPSF/GQ-02 inhibits the development of hepatic steatosis and inflammation in a mouse model of non-alcoholic fatty liver disease (NAFLD) by Soares e Silva, Amanda Karolina, de Oliveira Cipriano Torres, Dilênia, dos Santos Gomes, Fabiana Oliveira, dos Santos Silva, Bruna, Lima Ribeiro, Edlene, Costa Oliveira, Amanda, dos Santos, Laise Aline Martins, de Lima, Maria do Carmo Alves, Pitta, Ivan da Rocha, Peixoto, Christina Alves

“…Non-alcoholic fatty liver disease (NAFLD) defines a wide spectrum of liver diseases that extends from simple steatosis to non-alcoholic steatohepatitis…”
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Xylans extracted from branches and leaves of Protium puncticulatum: antioxidant, cytotoxic, immunomodulatory, anticoagulant, antitumor, prebiotic activities and their structural characterization by da Cruz Filho, Iranildo José, de Souza, Thammyris Pires, dos Anjos Santos, Carolina Ávila, de Morais Araújo, Maria Augusta, de Oliveira Moraes Miranda, Josué Filipe, de Oliveira Queirós, Maria Emanuelle, Filho, Denilson José Nogueira Correia, da Conceição Alves de Lima, Alice, Marques, Diego Santa Clara, do Carmo Alves de Lima, Maria

“…This work aimed to isolate and characterize xylans from branches and leaves of Protium puncticulatum , in addition to evaluating its in vitro biological and…”
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Physical–chemical characterization of new anti-inflammatory agent (LPSF/GQ-130) and evaluation of its thermal compatibility with pharmaceutical excipients by de Medeiros Vieira, Amanda Carla Quintas, Marques, Graziella Silvestre, de Melo, Cybelly Marques, da Silva, Keyla Emanuelle Ramos, Rolim, Larissa Araújo, do Carmo Alves de Lima, Maria, Galdino, Suely Lins, da Rocha Pitta, Ivan, Neto, Pedro José Rolim

“…LPSF/GQ-130 is a drug candidate, according to reports about its significant anti-inflammatory activity and non-toxicity demonstrated in an acute preclinical…”
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Anti-inflammatory and anti-arthritic activities of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (β-lapachone) by Sitônio, Marília Maria, de Carvalho Júnior, Carlson H. R., Campos, Ingrid de A., Silva, José Bruno Nunes Ferreira, de Lima, Maria do Carmo Alves, Góes, Alexandre J. S., Maia, Maria Bernadete Sousa, Rolim Neto, Pedro J., Silva, Teresinha G.

“…Objective and design The purpose of this study was to evaluate the anti-inflammatory and anti-arthritic activities of…”
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Anti-inflammatory and antinociceptive activities of indole–imidazolidine derivatives by da Silva Guerra, Aline Stamford Henrique, do Nascimento Malta, Diana Jussara, Morais Laranjeira, Luana Priscilla, Souza Maia, Maria Bernadete, Cavalcanti Colaço, Nathália, do Carmo Alves de Lima, Maria, Galdino, Suely Lins, da Rocha Pitta, Ivan, Gonçalves-Silva, Teresinha

“…Non-steroidal anti-inflammatory drugs (NSAIDs) represent a group of approximately 50 different medicines that are widely prescribed for the management of…”
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Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition by Ribeiro, Amélia Galdino, Almeida, Sinara Mônica Vitalino de, de Oliveira, Jamerson Ferreira, Souza, Tulio Ricardo Couto de Lima, Santos, Keriolaine Lima dos, Albuquerque, Amanda Pinheiro de Barros, Nogueira, Mariane Cajuba de Britto Lira, Carvalho Junior, Luiz Bezerra de, Moura, Ricardo Olímpio de, da Silva, Aline Caroline, Pereira, Valéria Rêgo Alves, Castro, Maria Carolina Accioly Brelaz de, Lima, Maria do Carmo Alves de

“…Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were synthetized and their biological properties were investigated, among which, the…”
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5-nitro-thiophene-thiosemicarbazone derivative induces cell death, cell cycle arrest, and phospho-kinase shutdown in pancreatic ductal adenocarcinoma cells by Costa, Valécia de Cassia Mendonça da, Lima, Maria do Carmo Alves de, da Cruz Filho, Iranildo José, Galdino, Lília Vieira, Pereira, Michelly Cristiny, Silva, Bárbara de Oliveira, Albuquerque, Amanda Pinheiro de Barros, da Rosa, Michelle Melgarejo, Pitta, Maira Galdino da Rocha, Rêgo, Moacyr Jesus Barreto de Melo

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with limited treatment options. This study explores the potential of novel…”
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Synthesis, thermal behavior and biological evaluation of benzodioxole derivatives as potential cytotoxic and antiparasitic agents by Silva, Willams Leal, de Andrade, Fabricio Havy Dantas, Lins, Taynara Batista, da Silva, Anekécia Lauro, da Cruz Amorim, Cezar Augusto, dos Santos Lima, Maria Joanellys, da Silva, Paulo César Dantas, Vilela, Williana Tôrres, Nascimento, Pedro Henrique do Bomfim, de Oliveira, Jamerson Ferreira, de Souza, Fábio Santos, Alves de Lima, Maria do Carmo, da Silva, Rosali Maria Ferreira

“…Benzodioxole derivatives are known to possess a broad spectrum of activities such. In addition to the synthetic derivatives, natural products that have the…”
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Synthesis, DNA binding and topoisomerase I inhibition activity of thiazacridine and imidazacridine derivatives by Lafayette, Elizabeth Almeida, Vitalino de Almeida, Sinara Mônica, Pitta, Marina Galdino da Rocha, Carneiro Beltrão, Eduardo Isidoro, da Silva, Teresinha Gonçalves, Olímpio de Moura, Ricardo, Pitta, Ivan da Rocha, de Carvalho, Jr, Luiz Bezerra, de Lima, Maria do Carmo Alves

“…Thiazacridine and imidazacridine derivatives have shown promising results as tumors suppressors in some cancer cell lines. For a better understanding of the…”
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PPARγ partial agonist GQ-16 strongly represses a subset of genes in 3T3-L1 adipocytes by Milton, Flora Aparecida, Cvoro, Aleksandra, Amato, Angelica A., Sieglaff, Douglas H., Filgueira, Carly S., Arumanayagam, Anithachristy Sigamani, de Lima, Maria do Carmo Alves, Pitta, Ivan Rocha, de Assis Rocha Neves, Francisco, Webb, Paul

“…Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor gamma (PPARγ) agonists that improve insulin resistance but trigger side effects such…”
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Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma by Rêgo, Moacyr Jesus Barreto de Melo, Azoubel-Antunes, Adriana, Bezerra, Mariana Brayner-Cavalcanti Freire, Pereira, Michelly Cristiny, Silva, Juliana Cruz da, Lins, Thiago Ubiratan Lins e, Sarinho, Emanuel Sávio Cavalcanti, Amorim, Cézar Augusto da Cruz, Lima, Maria do Carmo Alves de, Galdino-Pitta, Marina Rocha, Pitta, Ivan da Rocha, Pitta, Maira Galdino da Rocha

“…Allergic asthma is a chronic, complex inflammatory disease of the airway. Despite extensive studies on the immunomodulation of T helper (Th) cell pathways…”
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Purification of juices extracted from Stevia rebaudiana leaves by salt precipitation by Cabanne, Marie, De Lima, Maria Thereza Alves, Khezzane, Montaine, Baillon, Fabien, Hastoy, Cécile, Boutie, Philippe, Espitalier, Fabienne

“…Stevia rebaudiana is a perennial herbaceous plant, part of the Asteraceae family and native of Paraguay [1]. It has been cultivated in China and Southeast Asia…”
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Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine by da Silva, Vinícius Barros Ribeiro, Campos, Bruna Rafaella Koresch Leiva, de Oliveira, Jamerson Ferreira, Decout, Jean-Luc, do Carmo Alves de Lima, Maria

“…[Display omitted] Neglected tropical diseases (NTDs) are a group of diseases that, besides prevailing in poverty conditions, contribute to the maintenance of…”
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Genotoxicity and Anticancer Effects of the Aminothiophene Derivatives SB-44, SB- 83, and SB-200 in Cancer Cells by da Silva, Eduardo Davi Lima, Dos Santos, Flaviana Alves, de Oliveira, Júlia Teixeira, Dos Santos, Fabio Vieira, Junior, Francisco Jaime Bezerra Mendonça, do Carmo Alves de Lima, Maria, da Rocha Pitta, Maira Galdino, de Jesus de Melo Rego, Moacyr Barreto, Pereira, Michelly Cristiny

“…Thiophene derivatives have been widely studied as promising options for the treatment of solid tumors. Previous studies have shown that thiophene derivatives…”
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Preformulation study of ivermectin raw material by Rolim, Larissa Araújo, dos Santos, Flávia Cássia Maria, Chaves, Luíse Lopes, Gonçalves, Maria Luíza Carneiro Moura, Freitas-Neto, José Lourenço, da Silva do Nascimento, André Luiz, Soares-Sobrinho, José Lamartine, de Albuquerque, Miracy Muniz, do Carmo Alves de Lima, Maria, Rolim-Neto, Pedro José

“…The aim of this study was to characterize the raw material ivermectin (IVC) using different analytical techniques used for drugs with its pharmacological…”
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New imidazolidine derivatives as anti-Trypanosoma cruzi agents: structure–activity relationships by dos Santos Gomes, Fabiana Oliveira, de Melo, Cristiane Moutinho Lagos, Peixoto, Christina Alves, de Lima, Maria do Carmo Alves, Galdino, Suely Lins, Pereira, Valéria Rêgo Alves, da Rocha Pitta, Ivan

“…Imidazolidine derivatives are key components for the development of bioactive compounds for the treatment of many diseases, especially Chagas. In fact, others…”
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ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation by Albino, Sonaly Lima, da Silva Moura, Willian Charles, Reis, Malu Maria Lucas Dos, Sousa, Gleyton Leonel Silva, da Silva, Pablo Rayff, de Oliveira, Mayara Gabriele Carvalho, Borges, Tatiana Karla Dos Santos, Albuquerque, Lucas Fraga Friaça, de Almeida, Sinara Mônica Vitalino, de Lima, Maria do Carmo Alves, Kuckelhaus, Selma Aparecida Souza, Nascimento, Igor José Dos Santos, Junior, Francisco Jaime Bezerra Mendonca, da Silva, Teresinha Gonçalves, de Moura, Ricardo Olímpio

“…The present study proposed the synthesis of a novel acridine derivative not yet described in the literature, chemical characterization by NMR, MS, and IR,…”
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Lignin isolated from Caesalpinia pulcherrima leaves has antioxidant, antifungal and immunostimulatory activities by de Melo, Cristiane Moutinho Lagos, da Cruz Filho, Iranildo José, de Sousa, Georon Ferreira, de Souza Silva, Guilherme Antonio, do Nascimento Santos, Dayane Kelly Dias, da Silva, Ricardo Sérgio, de Sousa, Bruna Rodrigues, de Lima Neto, Reginaldo Gonçalves, do Carmo Alves de Lima, Maria, de Moraes Rocha, George Jackson

“…Caesalpinia pulcherrima is a shrub with worldwide distribution used as an ornamental plant. In this study, we extracted a lignin from the C. pulcherrima leaves…”
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