Search Results - "Maria de Fátima Cepa Matos"
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Cytotoxic Evaluation of Phenolic Compounds from Lichens against Melanoma Cells
Published in Chemical & pharmaceutical bulletin (01-02-2013)“…Atranorin, lichexanthone, and the (+)-usnic, diffractaic, divaricatic, perlatolic, psoromic, protocetraric, and norstictic acids isolated from the lichens…”
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Effects of Fumarprotocetraric Acid, a Depsidone from the Lichen Cladonia verticillaris, on Tyrosinase Activity
Published in Orbital : The Electronic Journal of Chemistry (01-07-2017)“…Lichens are widely distributed around the world. Their phenolic compounds, consisting mainly of depsides and depsidones, have been extensively studied for…”
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Cytotoxic Phenanthrene, Dihydrophenanthrene, and Dihydrostilbene Derivatives and Other Aromatic Compounds from Combretum laxum
Published in Molecules (Basel, Switzerland) (10-07-2020)“…The chemical investigation of the roots and stems of yielded a new dihydrostilbene derivative,…”
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Evaluation of the Antitumor Potential of the Resorcinolic Lipid 3-Heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one in Breast Cancer Cells
Published in Anticancer research (01-08-2018)“…In recent years, the search for new anticancer experimental agents derived from natural products or synthetic analogues, such as resorcinolic lipids, has…”
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In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species
Published in Pharmaceutical biology (01-12-2017)“…Context: New antileishmanias are needed because of toxicity, high cost and resistance problems associated with available drugs. Nectandra (Lauraceae) produces…”
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Leishmania infection in blood donors: A new challenge in leishmaniasis transmission?
Published in PloS one (14-06-2018)“…Transfusion-transmitted leishmaniasis has been a concern in regions endemic for the disease. Whether immediate or delayed, the risks posed by this mode of…”
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In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii
Published in Memórias do Instituto Oswaldo Cruz (01-03-2016)“…The polar hydroethanolic extract from Selaginella sellowii (SSPHE) has been previously proven active on intracellular amastigotes (in vitro test) and now was…”
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Actions of sesquiterpene lactones isolated from Moquiniastrum polymorphum subsp. floccosum in MCF7 cell line and their potentiating action on doxorubicin
Published in BMC pharmacology & toxicology (29-06-2017)“…In order to obtain better clinical results in anticancer therapies, polychemotherapy or combination therapies are used. For this, the combinations are required…”
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In vitro Antitumour Activity of Orsellinates
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-01-2010)“…Lichen phenolic compounds exhibit antioxidant, antimicrobial, antiproliferative, and cytotoxic activities. The purpose of this study was to evaluate the…”
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Evaluation of in vitro toxicity of hydroxyapatite doped with gallium
Published in Materials letters (15-10-2019)“…[Display omitted] •Hydroxyapatite doped with gallium.•Toxicity evaluation.•Orthopedic applications. The objective of this study was to evaluate the in vitro…”
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Chemical Composition and Evaluation of Antitumoral Activity of Leaf and Root Essential Oils of Conyza canadensis (Asteraceae)
Published in Orbital : The Electronic Journal of Chemistry (01-07-2019)“…The leaf and root oils of Conyza canadensis were studied for chemical composition and antitumor activity. The results showed that there is a significant…”
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Molecular characterization of Candida spp. isolates from patients with bloodstream infections
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-11-2013)“…The aim of this study was to conduct an epidemiological study comparing the genetic similarity of yeasts isolated from blood cultures. Random amplification of…”
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Cytotoxic alkaloids from Pogonopus tubulosus: G2/M cell cycle arrest and inhibition of DNA topoisomerase IIα by isotubulosine
Published in Phytotherapy research (01-05-2018)“…Phytochemical investigation of Pogonopus tubulosus trunk led to the isolation of isotubulosine and alangiside, tetrahydroisoquinoline indolic monoterpene…”
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Increment of antimycobaterial activity on lichexanthone derivatives
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-11-2013)“…A new dihydropyranexanthone derived from the natural xanthone lichexanthone (1) was synthesised and, together with other 18 derivatives including ω-bromo and…”
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Chemical modifications of a natural xanthone and antimicrobial activity against multidrug resistant Staphylococcus aureus and cytotoxicity against human tumor cell lines
Published in Química Nova (2011)“…A series of 15 ω-aminoalkoxylxanthones containing methyl, ethyl, propyl, tert-butylamino and piperidinyl moieties were synthesized from a natural xanthone…”
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Thiopyrimidine derivatives induce cytotoxicity, cell cycle arrest and oxidative stress in breast cancer 3D-spheroids
Published in Chemical papers (01-03-2021)“…3D-cultured breast cancer cells had shown relative drug resistance as compared to 2D-cultured cells, and it has been suggested as a new in vitro cell-based…”
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Antitumor effect of depsidones from lichens on tumor cell lines and experimental murine melanoma
Published in Revista brasileira de farmacognosia (01-07-2019)“…[Display omitted] Lichens have exhibited numerous biological activities, including growth inhibition of tumor cells. This study evaluated the antiproliferative…”
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Application of Fenton, photo-Fenton, solar photo-Fenton, and UV/H2O2 to degradation of the antineoplastic agent mitoxantrone and toxicological evaluation
Published in Environmental science and pollution research international (01-04-2013)“…In the present study, selected advanced oxidation processes (AOPs)—namely, photo-Fenton (with Fe 2+ , Fe 3+ , and potassium ferrioxalate—FeOx—as iron sources),…”
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In vitro activity of the hydroethanolic extract and biflavonoids isolated from Selaginella sellowii on Leishmania (Leishmania) amazonensis
Published in Memórias do Instituto Oswaldo Cruz (01-12-2014)“…This study is the first phytochemical investigation of Selaginella sellowii and demonstrates the antileishmanial activity of the hydroethanolic extract from…”
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Effect of Powdered Shells of the Snail Megalobulimus lopesi on Secondary-Intention Wound Healing in an Animal Model
Published in Evidence-based complementary and alternative medicine (01-01-2015)“…Topical administration of powdered shells of the land snail Megalobulimus lopesi was evaluated in Wistar rats for their healing activity in an excision wound…”
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