Search Results - "Maria Volpato, Nadia"

In vitro toxic evaluation of two gliptins and their main impurities of synthesis by Giordani, Camila F A, Campanharo, Sarah, Wingert, Nathalie R, Bueno, Lívia M, Manoel, Joanna W, Costa, Barbara, Cattani, Shanda, Arbo, Marcelo Dutra, Garcia, Solange Cristina, Garcia, Cássia Virginia, Volpato, Nádia Maria, Schapoval, Elfrides Eva Scherman, Steppe, Martin

“…The presence of impurities in some drugs may compromise the safety and efficacy of the patient's treatment. Therefore, establishing of the biological safety of…”
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The application of quality by design in the development of the liquid chromatography method to determine empagliflozin in the presence of its organic impurities by Manoel, Joanna Wittckind, Primieri, Gabriele Bordignon, Bueno, Lívia Maronesi, Wingert, Nathalie Ribeiro, Volpato, Nádia Maria, Garcia, Cássia Virginia, Scherman Schapoval, Elfrides Eva, Steppe, Martin

“…Analysis of impurities is an important step in the quality control of pharmaceutical ingredients and final products. From drug synthesis or excipients, even in…”
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HPLC method for simultaneous analysis of ticagrelor and its organic impurities and identification of two major photodegradation products by Bueno, Lívia Maronesi, Manoel, Joanna Wittckind, Giordani, Camila Ferrazza Alves, Mendez, Andreas Sebastian Loureiro, Volpato, Nadia Maria, Schapoval, Elfrides Eva Scherman, Steppe, Martin, Garcia, Cássia Virginia

“…A simple, fast and sensitive analytical method by high-performance liquid chromatography (HPLC) was developed and validated for the simultaneous determination…”
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UPLC-ESI/Q-TOF MS/MS Method for Determination of Vildagliptin and its Organic Impurities by Ferrazza Alves Giordani, Camila, Campanharo, Sarah, Ribeiro Wingert, Nathalie, Maronesi Bueno, Lívia, Wittckind Manoel, Joanna, Virginia Garcia, Cássia, Maria Volpato, Nadia, Dineck Iop, Gabrielle, de Azevedo Mello, Paola, Marlon de Moraes Flores, Erico, Eva Scherman Schapoval, Elfrides, Steppe, Martin

“…Abstract Vildagliptin (VLG) corresponds to a drug used for the treatment of diabetes mellitus. This disease requires continuous treatment, and so the control…”
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Gemifloxacin mesylate (GFM): dissolution test based on in vivo data by Paim, Clésio Soldateli, Araújo, Bibiana Verlindo de, Volpato, Nádia Maria, Steppe, Martin, Schapoval, Elfrides Eva Sherman

“…Abstract Gemifloxacin mesylate (GFM) is a synthetic, broad-spectrum, fluoroquinolone antibacterial agent. It is different from other class members because it…”
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In vitro evaluation of cutaneous penetration of acyclovir from semisolid commercial formulations and relation with its effective antiviral concentration by Sponchiado, Rafaela Martins, Cordenonsi, Leticia Malgarim, Wingert, Nathalie Ribeiro, Araujo, Bibiana Verlindo de, Volpato, Nadia Maria

“…The evaluation of drug permeation/penetration of semisolid formulations into animal skin can be useful to supplement the pharmaceutical equivalence. This paper…”
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Production of PMMA Nanoparticles Loaded with Praziquantel Through "In Situ" Miniemulsion Polymerization by Fonseca, Laís B., Nele, Márcio, Volpato, Nádia Maria, Seiceira, Rafael C., Pinto, José Carlos

“…PZQ is the primary drug for treatment of schistosomiasis, but its efficiency is severely affected by its bitter taste. The main objective of this paper is the…”
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Influence of the calcium concentration in the presence of organic phosphorus on the physicochemical compatibility and stability of all-in-one admixtures for neonatal use by Ribeiro, Daniela de Oliveira, Lobo, Bianca Waruar, Volpato, Nádia Maria, da Veiga, Venício Féo, Cabral, Lúcio Mendes, de Sousa, Valeria Pereira

“…Preterm infants need high amounts of calcium and phosphorus for bone mineralization, which is difficult to obtain with parenteral feeding due to the low…”
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New microencapsulation system for ascorbic acid using pea protein concentrate as coat protector by Pierucci, Anna Paola T. R., Andrade, Leonardo R., Baptista, Edilene B., Volpato, Nádia Maria, Rocha-Leão, Maria Helena M.

“…Microencapsulation is essential to preserve biological activity of ascorbic acid (AA) and pea protein has not been used as a carrier in such processes. This…”
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Development of a brazilian nanoencapsulated drug for schistosomiasis treatment by Da Fonseca, Laís Bastos, Viçosa, Alessandra Lifsitch, Mattos, Ana Carolina Alves, Coelho, Paulo Marcos Zech, Araújo, Neusa, Zamith, Helena Pereira da Silva, Volpato, Nadia Maria, Nele, Márcio, Pinto, José Carlos Costa da Silva

“…Schistosomiasis is a parasitic disease that, according to the World Health Organization, constitutes a major public health problem associated with severe…”
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Development and validation of a dissolution test for empagliflozin in film-coated tablets by Manoel, Joanna Wittckind, Primieri, Gabriele Bordignon, Volpato, Nadia Maria, Steppe, Martin

“…The present study proposes a validated dissolution method for empagliflozin (EMPA) in film coated tablets. A gradual in vitro dissolution profile for this…”
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Development of nanoemulsions containing penciclovir for herpes simplex treatment and a liquid chromatographic method to drug assessment in porcine skin layers by Meira, Alianise Da Silva, Battistel, Ana Paula, Teixeira, Helder Ferreira, Volpato, Nadia Maria

“…A successful formulation (penciclovir hydrogel nanoemulsion - HN) to be used in transdermal drug delivery route to treat herpes simplex virus was developed and…”
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On-line solid-phase extraction coupled with high-performance liquid chromatography and tandem mass spectrometry (SPE-HPLC-MS-MS) for quantification of bromazepam in human plasma: an automated method for bioequivalence studies by Gonçalves, José Carlos Saraiva, Monteiro, Tânia Maria, Neves, Claúdia Silvana de Miranda, Gram, Karla Regina da Silva, Volpato, Nádia Maria, Silva, Vivian A, Caminha, Ricardo, Gonçalves, Maria do Rocio Bencke, Santos, Fábio Monteiro Dos, Silveira, Gabriel Estolano da, Noël, François

“…A validated method for on-line solid-phase extraction coupled with high-performance liquid chromatography tandem mass spectrometry (SPE-HPLC-MS-MS) is…”
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Evaluation of linagliptin dissolution from tablets using HPLC and UV methods by De Abreu Engel, Rita Elena, Thomas Barden, Amanda, Chagas Campanharo, Sarah, Olegário, Natália, Volpato, Nadia Maria, Scherman Schapoval, Elfrides Eva

“…Linagliptin (LGT) is used to reduce glucose blood levels in patients with type 2 Diabetes mellitus. The proposed conditions for a biowaiver guide can be…”
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SECOND-ORDER DERIVATIVE UV SPECTROPHOTOMETRIC AND RP-HPLC METHODS FOR THE ANALYSIS OF VILDAGLIPTIN AND APPLICATION FOR DISSOLUTION STUDY by Thomas Barden, Amanda, Piccoli, Bruna L, Volpato, Nadia Maria, Steppe, Martin

“…This study describes two analytical methods, by second-order derivative UV spectrophotometric by HPLC, for determination of vildagliptin, a drug used for…”
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Evaluation of porcine skin layers separation methods, freezing storage and anatomical site in in vitro percutaneous absorption studies using penciclovir formulations by Meira, Alianise da Silva, Battistel, Ana Paula, Teixeira, Helder Ferreira, Volpato, Nadia Maria

“…Literature reveals high variation in the techniques used for in vitro studies of percutaneous absorption, resulting in several outcomes and making it difficult…”
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Development, Quality by Design-Based Optimization, and Stability Assessment of Oral Liquid Formulations Containing Baclofen for Hospital Use by de Saldanha Simon, Elisa, Wingert, Nathalie Ribeiro, Gobetti, Caren, Primieri, Gabriele Bordignon, Ayres, Márcio Vinícius, de Almeida, Silvia Helena Oliveira, Volpato, Nadia Maria, Steppe, Martin

“…The absence of oral liquid pharmaceutical forms appropriate for use in pediatric and adult patients with difficulty swallowing is a public health problem,…”
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CHARACTERIZATION OF LINAGLIPTIN USING ANALYTICAL TECHNIQUES by Thomas Barden, Amanda, De Abreu Engel, Rita Elena, Chagas Campanharo, Sarah, Volpato, Nadia Maria, Scherman Schapoval, Elfrides Eva

“…Linagliptin (LGT) is a member of the class of gliptins that inhibit the enzyme dipeptidyl-peptidase-4. They are used to reduce glucose blood levels in patients…”
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UV SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE DETERMINATION OF AGOMELATINE IN COATED TABLETS by De Souza Barbosa, Fábio, Coty Rodrigues, Vanise, Volpato, Nadia Maria, S. Schapoval, Elfrides E., Steppe, Martin, Garcia, Cássia V., L. Mendez, Andreas S.

“…UV spectrophotometry is an analytical technique used routinely for qualitative and quantitative assay due the low cost and reliability during analysis. In this…”
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Analytical Quality by Design Approach for a Stability-Indicating Method to Determine Apixaban and Its Related Impurities by Ellwanger, Jéssica B., Wingert, Nathalie Ribeiro, Volpato, Nadia Maria, Garcia, Cássia Virginia, Schapoval, Elfrides E. S., Steppe, Martin

“…Quality by Design (QbD) is a systematic approach that takes predefined objectives and emphasizes process understanding and control. Analytical QbD (AQbD) is…”
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