Search Results - "Maria Pilar Andueza"
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Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs)
Published in Clinical cancer research (01-08-2016)“…Myeloid-derived suppressor cells (MDSC) are considered an important T-cell immunosuppressive component in cancer-bearing hosts. The factors that attract these…”
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Published in Immunity (Cambridge, Mass.) (19-05-2020)“…Neutrophils are expanded and abundant in cancer-bearing hosts. Under the influence of CXCR1 and CXCR2 chemokine receptor agonists and other chemotactic factors…”
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Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced lung cancer
Published in Cancer medicine (Malden, MA) (01-07-2018)“…Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome‐wide association study to characterize…”
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Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins
Published in Clinical cancer research (15-11-2014)“…Interleukin-8 (IL8) is a chemokine produced by malignant cells of multiple cancer types. It exerts various functions in shaping protumoral vascularization and…”
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Differential Interleukin‐8 thresholds for chemotaxis and netosis in human neutrophils
Published in European journal of immunology (01-09-2021)“…In humans, IL‐8 (CXCL8) is a key chemokine for chemotaxis of polymorphonuclear leukocytes and monocytes/macrophages when acting on CXCR1 and CXCR2. CXCL8…”
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Whole exome sequencing and machine learning germline analysis of individuals presenting with phenotypes of extreme high and low risk of developing tobacco-induced lung adenocarcinoma
Published in Journal of clinical oncology (01-06-2023)“…10507 Background: Tobacco is the main risk factor for developing lung cancer. Yet, while some heavy smokers develop lung cancer at young age others never…”
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Whole exome sequencing of germline DNA of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung adenocarcinoma (LUAD) according to KRAS status
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 1540 Background: Individual susceptibility to carcinogens may depend on the genetic background. We characterized the constitutional exome of…”
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Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma
Published in EBioMedicine (01-04-2024)“…Tobacco is the main risk factor for developing lung cancer. Yet, while some heavy smokers develop lung cancer at a young age, other heavy smokers never develop…”
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Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinomaResearch in context
Published in EBioMedicine (01-04-2024)“…Background: Tobacco is the main risk factor for developing lung cancer. Yet, while some heavy smokers develop lung cancer at a young age, other heavy smokers…”
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Thymidylate synthase (TS) polymorphisms (Pol) in buffy coat-derived genomic DNA as a clinical outcome predictor in non-Asian stage III/IV non-small cell lung cancer (NSCLC) patients (pts) receiving pemetrexed (Pem)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e19112 Background: TS is the main biological target of the antifolate Pem. Some TS Pol may confer a short survival and a poor response to…”
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Identification through genome-wide association study (GWAS) of single nucleotide polymorphisms (SNPs) associated with extreme phenotypes of tobacco-induced non-small cell lung cancer (NSCLC) risk
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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El Catálogo Monumental y Artístico de la provincia de Navarra de 1916: crónica de una oportunidad perdida
Published in Ars Bilduma (27-05-2020)“…Siguiendo sendos reales decretos de 1900 y 1902 que ordenaban recoger "todas las riquezas monumentales y artísticas" de la nación, en 1916 se encargó al…”
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