Search Results - "Maria Hernandez, Rosa"

Chronic wounds: Current status, available strategies and emerging therapeutic solutions by Las Heras, Kevin, Igartua, Manoli, Santos-Vizcaino, Edorta, Hernandez, Rosa Maria

“…In the past decades, adequate and well-planned management of chronic wounds has reached an elevated importance to improve human's quality of life and extend…”
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Nanotherapeutic approaches for brain cancer management by Saenz del Burgo, Laura, PhD, Hernández, Rosa María, PhD, Orive, Gorka, PhD, Pedraz, Jose Luis, PhD

“…Abstract Around the world, cancer remains one of the most important causes of morbidity and mortality. Worldwide, approximately 238,000 new cases of brain and…”
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Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation by Hernando, Sara, Requejo, Catalina, Herran, Enara, Ruiz-Ortega, Jose Angel, Morera-Herreras, Teresa, Lafuente, Jose Vicente, Ugedo, Luisa, Gainza, Eusebio, Pedraz, Jose Luis, Igartua, Manoli, Hernandez, Rosa Maria

“…Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been widely associated to beneficial effect over different neurodegenerative diseases. In the present…”
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Mesenchymal Stromal Cell Secretome for the Treatment of Immune-Mediated Inflammatory Diseases: Latest Trends in Isolation, Content Optimization and Delivery Avenues by Munoz-Perez, Elena, Gonzalez-Pujana, Ainhoa, Igartua, Manoli, Santos-Vizcaino, Edorta, Hernandez, Rosa Maria

“…Considering the high prevalence and the complex pharmacological management of immune-mediated inflammatory diseases (IMIDs), the search for new therapeutic…”
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Nanoparticle transport across in vitro olfactory cell monolayers by Gartziandia, Oihane, Egusquiaguirre, Susana Patricia, Bianco, John, Pedraz, José Luis, Igartua, Manoli, Hernandez, Rosa Maria, Préat, Véronique, Beloqui, Ana

“…[Display omitted] Drug access to the CNS is hindered by the presence of the blood–brain barrier (BBB), and the intranasal route has risen as a non-invasive…”
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3D Bioprinting of Functional Skin Substitutes: From Current Achievements to Future Goals by Manita, Paula Gabriela, Garcia-Orue, Itxaso, Santos-Vizcaino, Edorta, Hernandez, Rosa Maria, Igartua, Manoli

“…The aim of this review is to present 3D bioprinting of skin substitutes as an efficient approach of managing skin injuries. From a clinical point of view,…”
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Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing by Las Heras, Kevin, Royo, Félix, Garcia-Vallicrosa, Clara, Igartua, Manoli, Santos-Vizcaino, Edorta, Falcon-Perez, Juan M, Hernandez, Rosa Maria

“…Mesenchymal stromal cells (MSCs) and their extracellular vesicles (MSC-EVs) have demonstrated to elicit immunomodulatory and pro-regenerative properties that…”
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Development of Bioinspired Gelatin and Gelatin/Chitosan Bilayer Hydrofilms for Wound Healing by Garcia-Orue, Itxaso, Santos-Vizcaino, Edorta, Etxabide, Alaitz, Uranga, Jone, Bayat, Ardeshir, Guerrero, Pedro, Igartua, Manoli, de la Caba, Koro, Hernandez, Rosa Maria

“…In the current study, we developed a novel gelatin-based bilayer wound dressing. We used different crosslinking agents to confer unique properties to each…”
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The synergistic effects of the RGD density and the microenvironment on the behavior of encapsulated cells: In vitro and in vivo direct comparative study by Santos, Edorta, Garate, Ane, Pedraz, José Luis, Orive, Gorka, Hernández, Rosa María

“…The inclusion of the tripeptide RGD (Arg‐Gly‐Asp) in otherwise inert biomaterials employed for cell encapsulation has been observed to be an effective strategy…”
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Nanostructured Lipid Carriers Made of Ω-3 Polyunsaturated Fatty Acids: In Vitro Evaluation of Emerging Nanocarriers to Treat Neurodegenerative Diseases by Hernando, Sara, Herran, Enara, Hernandez, Rosa Maria, Igartua, Manoli

“…Neurodegenerative diseases (ND) are one of the main problems of public health systems in the 21st century. The rise of nanotechnology-based drug delivery…”
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Immunomodulatory Biomaterials for Tissue Repair by Whitaker, Ricardo, Hernaez-Estrada, Beatriz, Hernandez, Rosa Maria, Santos-Vizcaino, Edorta, Spiller, Kara L

“…All implanted biomaterials are targets of the host’s immune system. While the host inflammatory response was once considered a detrimental force to be blunted…”
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Overcoming the Inflammatory Stage of Non-Healing Wounds: In Vitro Mechanism of Action of Negatively Charged Microspheres (NCMs) by Santos-Vizcaino, Edorta, Salvador, Aiala, Vairo, Claudia, Igartua, Manoli, Hernandez, Rosa Maria, Correa, Luis, Villullas, Silvia, Gainza, Garazi

“…Negatively charged microspheres (NCMs) represent a new therapeutic approach for wound healing since recent clinical trials have shown NCM efficacy in the…”
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Prenatal p,p´-DDE exposure and neurodevelopment among children 3.5-5 years of age by Torres-Sánchez, Luisa, Schnaas, Lourdes, Rothenberg, Stephen J, Cebrián, Mariano E, Osorio-Valencia, Erika, Hernández, María del Carmen, García-Hernández, Rosa María, López-Carrillo, Lizbeth

“…The results of previous studies suggest that prenatal exposure to bis[p-chlorophenyl]-1,1,1-trichloroethane (DDT) and to its main metabolite,…”
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The Role of Lipid Nanoparticles and its Surface Modification in Reaching the Brain: An Approach for Neurodegenerative Diseases Treatment by Hernando, Sara, Pedraz, Jose Luis, Igartua, Manoli, Hernandez, Rosa Maria

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Prehabilitation for Bariatric Surgery: A Randomized, Controlled Trial Protocol and Pilot Study by García-Delgado, Yaiza, López-Madrazo-Hernández, María José, Alvarado-Martel, Dácil, Miranda-Calderín, Guillermo, Ugarte-Lopetegui, Arantza, González-Medina, Raúl Alberto, Hernández-Lázaro, Alba, Zamora, Garlene, Pérez-Martín, Nuria, Sánchez-Hernández, Rosa María, Ibarra-González, Adriana, Bengoa-Dolón, Mónica, Mendoza-Vega, Carmen Teresa, Appelvik-González, Svein Mikael, Caballero-Díaz, Yurena, Hernández-Hernández, Juan Ramón, Wägner, Ana María

“…Bariatric surgery is the most efficacious treatment for obesity, though it is not free from complications. Preoperative conditioning has proved beneficial in…”
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Structure-properties relationship of chitosan/collagen films with potential for biomedical applications by Andonegi, Mireia, Heras, Kevin Las, Santos-Vizcaíno, Edorta, Igartua, Manoli, Hernandez, Rosa Maria, de la Caba, Koro, Guerrero, Pedro

“…•Chitosan addition preserved the triple-helix structure of native collagen.•There was no need to add chemical crosslinkers into chitosan/collagen…”
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The role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics by Gonzalez-Pujana, Ainhoa, Rementeria, Aitor, Blanco, Francisco Javier, Igartua, Manoli, Pedraz, Jose Luis, Santos-Vizcaino, Edorta, Hernandez, Rosa Maria

“…Transplantation of cells within alginate microspheres has been extensively studied for sustained drug delivery. However, the lack of control over cell behavior…”
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Behaviour and ultrastructure of human bone marrow-derived mesenchymal stem cells immobilised in alginate-poly-l-lysine-alginate microcapsules by Attia, Noha, Santos, Edorta, Abdelmouty, Hala, Arafa, Samia, Zohdy, Nahed, Hernández, Rosa María, Orive, Gorka, Pedraz, José Luis

“…Abstract Context: Human bone marrow mesenchymal stem cells (hBM-MSCs) show a great promise for the treatment of a variety of diseases. Despite the previous…”
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Microencapsulated macrophages releases conditioned medium able to prevent epithelial to mesenchymal transition by Sola, Anna, Saenz del Burgo, Laura, Ciriza, Jesús, Hernandez, Rosa Maria, Orive, Gorka, Martin Cordero, Jorge, Calle, Priscila, Pedraz, Jose Luis, Hotter, Georgina

“…Epithelial to mesenchymal transition (EMT) has emerged as a key process in the development of renal fibrosis. In fact, EMT-derived fibroblasts contribute to…”
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Chitosan coated nanostructured lipid carriers for brain delivery of proteins by intranasal administration by Gartziandia, Oihane, Herran, Enara, Pedraz, Jose Luis, Carro, Eva, Igartua, Manoli, Hernandez, Rosa Maria

“…[Display omitted] •Design and optimization of a chitosan coated nanostructured lipid carrier (CS-NLC) with the capacity to reach the brain after being…”
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