Search Results - "Maria Ghafoor"
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Stability, Intracellular Delivery, and Release of siRNA from Chitosan Nanoparticles Using Different Cross-Linkers
Published in PloS one (11-06-2015)“…Chitosan (CS) nanoparticles have been extensively studied for siRNA delivery; however, their stability and efficacy are highly dependent on the types of…”
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TYPE, TIME-TREND AND INDICATIONS OF HYSTERECTOMY
Published in Gomal journal of medical sciences (12-09-2019)“…ABSTRACT Background: The frequency of hysterectomy varies in same geographical area. The objectives of this study were to determine the type, time trend and…”
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FREQUENCY OF PRE-GESTATIONAL DIABETES MELLITUS AMONG PREGNANT WOMEN WITH MISCARRIAGE
Published in Gomal journal of medical sciences (31-03-2019)“…Background: In developing countries, miscarriage is one of the common and increasing problems of pregnancy. The objectives of this study were to determine the…”
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THIRTY DAY RE-ADMISSION RATE AFTER SHORT STAY HYSTERECTOMY
Published in Gomal journal of medical sciences (30-06-2018)“…Background: Concept of short stay surgery is getting popular globally to maximize use of available health resources. The objective of the study was to…”
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Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity
Published in The Journal of immunology (1950) (01-07-2024)“…Lymphocyte activation gene 3 (LAG3) is an inhibitory receptor that plays a critical role in controlling T cell tolerance and autoimmunity and is a major…”
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Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance
Published in European journal of medicinal chemistry (28-07-2017)“…The drug research and development nowadays is focusing on multi-target drugs. In the treatment of cancer, therapies using drugs inhibiting one numerous targets…”
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Thiolated Polymeric Hydrogels for Biomedical Applications: A Review
Published in Current pharmaceutical design (01-01-2023)“…Hydrogels are a three-dimensional (3D) network of hydrophilic polymers. The physical and chemical crosslinking of polymeric chains maintains the structure of…”
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Design, mechanism, delivery and therapeutics of canonical and Dicer-substrate siRNA
Published in Asian journal of pharmceutical sciences (01-09-2019)“…Upon the discovery of RNA interference (RNAi), canonical small interfering RNA (siRNA) has been recognized to trigger sequence-specific gene silencing. Despite…”
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Development of Chitosan Nanoparticles as a Stable Drug Delivery System for Protein/siRNA
Published in International Journal of Biomaterials (01-01-2013)“…Chitosan nanoparticles (CS NPs) exhibit good physicochemical properties as drug delivery systems. The aim of this study is to determine the modulation of…”
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Enhancement of Oral Bioavailability of Ibandronate Through Gastroretentive Raft Forming Drug Delivery System: In Vitro and In Vivo Evaluation
Published in International journal of nanomedicine (01-01-2020)“…Bisphosphonates have very low bioavailability and cause irritation of the esophagus and stomach. This study was planned to improve the oral bioavailability of…”
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Synthesis and mechanistic studies of curcumin analog‐based oximes as potential anticancer agents
Published in Chemical biology & drug design (01-09-2017)“…The incidence of cancer can be decreased by chemoprevention using either natural or synthetic agents. Apart from synthetic compounds, numerous natural products…”
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Solid Lipid Nanoparticles of Mycophenolate Mofetil: An Attempt to Control the Release of an Immunosuppressant
Published in International journal of nanomedicine (01-01-2020)“…Organ transplantation is a critically important procedure, which requires immune modulation by using immunosuppressants. Development of nanoparticles is an…”
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Synthesis of Thiol-Modified Hemicellulose, Its Biocompatibility, Studies, and Appraisal as a Sustained Release Carrier of Ticagrelor
Published in Frontiers in pharmacology (19-05-2021)“…Nature has always been considered as the primary source of pharmaceutical ingredients. A variety of hemicelluloses, as well as their modified forms, have been…”
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Formulation and evaluation of sustained release ocular inserts of betaxolol hydrochloride using arabinoxylan from Plantago ovata
Published in Pakistan journal of pharmaceutical sciences (01-05-2021)“…The purpose of the current studies was to develop ocular insert of betaxolol hydrochloride (BXH), using arabinoxylan (AX) as a film former. The inserts were…”
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Fabrication and Characterization of Matrix-Type Transdermal Patches Loaded with Ramipril and Repaglinide Through Cellulose-based Hydrophilic and Hydrophobic Polymers: In Vitro and Ex Vivo Permeation Studies
Published in Polymer-plastics technology and engineering (02-11-2017)“…Transdermal patches loaded with ramipril and repaglinide were prepared with the ambition to develop matrix-type transdermal drug delivery system for enhanced…”
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Predicting Big Babies: Using Amniotic Fluid and Baby Weight Estimates
Published in Annals of Punjab Medical College (30-09-2023)“…Background: Macrosomia or big baby is defined as a newborn with a birth weight of more than 4kg. Amniotic fluid index (AFI) which is estimated by adding length…”
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The prevalence of depression and associated factors among infertile couples
Published in The professional medical journal (01-03-2023)“…Objective: To determine the prevalence and significant associated factors of depression among infertile couples Study Design: Cross-sectional study. Setting:…”
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Correction: Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity
Published in The Journal of immunology (1950) (01-10-2024)Get full text
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Synthesis and biological evaluation of new tetramethylpyrazine‐based chalcone derivatives as potential anti‐Alzheimer agents
Published in Chemical biology & drug design (01-11-2018)“…In the current study, a series of new ligustrazine‐based chalcones was synthesized. For insertion of tetramethylpyrazine (TMP, also designated as ligustrazine)…”
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Rosuvastatin, Perindopril and Ezetimibe loaded instant release buccal films: Development and in vitro characterization
Published in Journal of applied biomedicine (01-12-2020)“…Rosuvastatin Calcium and Ezetimibe are used to control cholesterol level while Perindopril Erbumine is used to treat hypertension. Hepatic metabolism reduces…”
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