Search Results - "Maria D’Arco, Alfonso"
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Outcome prediction of diffuse large B-cell lymphomas associated with hepatitis C virus infection: a study on behalf of the Fondazione Italiana Linfomi
Published in Haematologica (Roma) (01-03-2014)“…A specific prognostication score for hepatitis C virus-positive diffuse large B-cell lymphomas is not available. For this purpose, the Fondazione Italiana…”
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Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial
Published in Journal of clinical oncology (20-02-2017)“…Purpose The initial results of the APL0406 trial showed that the combination of all- trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is at least not…”
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HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape
Published in Oncotarget (20-01-2015)“…Histone deacetylase 2 (HDAC2) is overexpressed or mutated in several disorders such as hematological cancers, and plays a critical role in transcriptional…”
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First Results of the Multicenter Total Therapy Gimema LAL 1509 Protocol for De Novo Adult Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Patients
Published in Blood (06-12-2014)“…▪ Introduction: Ph+ ALL management has changed since the introduction of tyrosine kinase inhibitors (TKI). In the GIMEMA LAL 1509 protocol for adult Ph+ ALL,…”
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Multicenter Total Therapy Gimema LAL 1509 Protocol for De Novo Adult Ph+ Acute Lymphoblastic Leukemia (ALL) Patients. Updated Results and Refined Genetic-Based Prognostic Stratification
Published in Blood (03-12-2015)“…Introduction: Management of Ph+ ALL has changed since the introduction of tyrosine kinase inhibitors (TKI). We previously reported the preliminary findings of…”
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Rituximab for warm-type idiopathic autoimmune hemolytic anemia: a retrospective study of 11 adult patients
Published in European journal of haematology (01-07-2007)“…Warm‐type idiopathic autoimmune hemolytic anemia (AIHA) is a relatively common hematologic disorder resulting from autoantibody production against red blood…”
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Rituximab therapy for chronic lymphocytic leukemia‐associated autoimmune hemolytic anemia
Published in American journal of hematology (01-08-2006)“…Autoimmune hemolytic anemia (AIHA) is a well‐known complication of chronic lymphocytic leukemia (CLL). In recent years the anti‐CD20 monoclonal antibody…”
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5-Azacytidine for the Treatment of Acute Myeloid Leukemia: A Retrospective, Multicenter Study of 55 Patients
Published in Blood (16-11-2008)“…5-Azacytidine (AZA) is an hypomethylating agent approved in US for the treatment of all FAB subtypes of myelodysplastic syndromes (MDS). Some recent reports…”
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Improved Outcome with ATRA-Arsenic Trioxide Compared to ATRA-Chemotherapy in Non-High Risk Acute Promyelocytic Leukemia – Updated Results of the Italian-German APL0406 Trial on the Extended Final Series
Published in Blood (06-12-2014)“…▪ Background: We recently showed that the combination of ATRA and arsenic trioxide (ATO) is at least not inferior and possibly superior to standard ATRA and…”
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MDS-391: Role of Erythropoiesis-Stimulating Agents (ESAs) in Supportive Care of Low-Risk Myelodysplastic Syndromes
Published in Clinical lymphoma, myeloma and leukemia (01-09-2020)“…Erythropoiesis-stimulating agents (ESAs) are the frontline treatment in low-risk anemic MDS patients, and employment of this therapy in the earlier stage of…”
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Azacitidine for the Treatment of Lower Risk Myelodysplastic Syndromes: A Retrospective Study of 74 Patients Enrolled in an Italian Named Patient Program
Published in Cancer (15-03-2010)“…Azacitidine induces responses and prolongs overall survival compared with conventional care regimens in patients who have high-risk myelodysplastic syndromes…”
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Bortezomib, thalidomide, and dexamethasone followed by double autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GIMEMA-MMY-3006): long-term follow-up analysis of a randomised phase 3, open-label study
Published in The Lancet. Haematology (01-12-2020)“…The phase 3 GIMEMA-MMY-3006 trial, which compared bortezomib, thalidomide, and dexamethasone (VTD) combination therapy with thalidomide and dexamethasone (TD)…”
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Feasibility and efficacy of dose‐dense and dose‐intense ABVD for high‐risk patients with advanced Hodgkin lymphoma
Published in British journal of haematology (01-11-2015)Get full text
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Lenalidomide in Combination with Bendamustine for Patients with Chemorefractory Hodgkin Lymphoma: Final Results of the Leben Multicenter Phase 1/2 Study
Published in Blood (03-12-2015)“…Background Improving strategies for patients (pts) with relapsed/refractory (R/R) Hodgkin lymphoma (HL) who fail stem cell transplantation (SCT) or are…”
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Lenalidomide treatment of myelodysplastic syndromes with chromosome 5q deletion: Results from the National Registry of the Italian Drug Agency
Published in European journal of haematology (01-07-2018)“…Objective The most typical cytogenetic aberration in myelodysplastic syndromes is del(5q), which, when isolated, is associated with refractory anaemia and good…”
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5-Azacytidine in 82 Low/Intermediate-1 IPSS Risk Myelodysplastic Syndromes: Results from the Italian Patient Named Program
Published in Blood (16-11-2008)“…5-azacytidine (AZA) significantly prolonged overall survival in higher-risk patients with myelodysplastic syndromes (MDS) in a large, international,…”
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Final Report of Bendamustine and Alemtuzumab (BEN CAM) Combination in Relapsed and Refractory Chronic Lymphocytic Leukemia
Published in Blood (16-11-2012)“…Abstract 2898 Notwithstanding the improved results with first-line therapy, CLL remains incurable, and patients are destined to relapse after primary…”
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Deferasirox Chelation Therapy in Transfusion Dependent MDS Patients. Final Report From the Gimema MDS0306 Prospective Trial
Published in Blood (16-11-2012)“…Abstract 425 FDA and EMA have approved Deferasirox for iron chelation therapy for transfusion dependent MDS patients after a limited experience in selected MDS…”
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Inhibition Of Histone Deacetylases With Panobinostat As a Treatment For Relapsed Or Refractory Diffuse Large B-Cell Lymphoma: A Phase II Study By The Fondazione Italiana Linfomi
Published in Blood (15-11-2013)“…Histone deacetylases (DACs) are involved in chromatin structure regulation and function. Treatment with DACs inhibitors leads to the activation or repression…”
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