Search Results - "Maria Cláudia Santos- Silva"
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The relationship between peripheral immune response and disease severity in SARS‐CoV‐2‐infected subjects: A cross‐sectional study
Published in Immunology (01-04-2022)“…Coronavirus disease 2019 (COVID‐19) is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and marked by an intense…”
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T cell maturation is significantly affected by SARS‐CoV‐2 infection
Published in Immunology (01-07-2023)“…Coronavirus disease 2019 (COVID‐19) is a respiratory tract infection caused by the new severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). An…”
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Involvement of the NF‐κB and PI3K/Akt/mTOR pathways in cell death triggered by stypoldione, an o‐quinone isolated from the brown algae Stypopodium zonale
Published in Environmental toxicology (01-06-2022)“…Multiple myeloma (MM) is a clonal plasma cell malignancy that remains incurable to date. Thus, the aims of this study were to evaluate the involvement of the…”
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PEO-chitosan nanofibers containing carboxymethyl-hexanoyl chitosan/dodecyl sulfate nanoparticles loaded with pyrazoline for skin cancer treatment
Published in European polymer journal (01-10-2019)“…[Display omitted] •A novel double-barrier nanomaterial (nanoparticles into nanofibers) was formed.•The nanoparticles increased the hydrophilicity of the…”
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Importance of Detecting Multidrug Resistance Proteins in Acute Leukemia Prognosis and Therapy
Published in Journal of clinical laboratory analysis (01-01-2013)“…Multidrug resistance (MDR) is a multifactorial phenomenon and the role of these proteins in generating the MDR phenotype is controversial. With this in mind,…”
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Induction of apoptosis and cell cycle arrest in L-1210 murine lymphoblastic leukaemia cells by (2E)-3-(2-naphthyl)-1-(3′-methoxy-4′-hydroxy-phenyl)-2-propen-1-one
Published in Journal of pharmacy and pharmacology (01-09-2010)“…Objectives New compounds with biological targets and less cytotoxicity to normal cells are necessary for cancer therapy. In this work ten synthetic chalcones…”
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Effect of nitric oxide on the daunorubicin efflux mechanism in K562 cells
Published in Cell biology international (01-06-2012)“…NO (nitric oxide) donating drugs have been investigated for their important role in the sensitization of neoplastic cells to chemotherapy drugs. The goal of…”
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Flow cytometry immunophenotyping as an important tool for rapid diagnosis of oral non-Hodgkin’s lymphoma
Published in Oral oncology (01-12-2022)Get full text
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Investigation of cellular mechanisms involved in apoptosis induced by a synthetic naphthylchalcone in acute leukemia cell lines
Published in Anti-cancer drugs (01-09-2016)“…We have previously reported the cytotoxic effects of chalcone A1, derived from 1-naphthaldehyde, in leukemia cell lines. On the basis of these findings, the…”
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Orally Administered Chitosan-Coated Polycaprolactone Nanoparticles Containing Curcumin Attenuate Metastatic Melanoma in the Lungs
Published in Journal of pharmaceutical sciences (01-10-2015)“…The study was aimed to evaluate the effect of orally administered chitosan-coated nanoparticles containing curcumin on metastatic melanoma. Chitosan-coated…”
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Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors
Published in European journal of medicinal chemistry (01-05-2013)“…Based on classical colchicine site ligands and a computational model of the colchicine binding site on beta tubulin, two classes of chalcone derivatives were…”
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Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells
Published in Journal of pharmacy & pharmaceutical sciences (2021)“…Current therapies for acute leukemias (ALs) are associated with severe adverse reactions and high relapse rates, which makes the search for new antileukemic…”
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Stealth and non-stealth nanocapsules containing camptothecin: in-vitro and in-vivo activity on B16-F10 melanoma
Published in Journal of pharmacy and pharmacology (01-10-2007)“…Camptothecin (CPT) is an alkaloid that displays considerable antitumour activity, but clinical use has been limited by its poor water solubility and the…”
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Molecular events and cytotoxic effects of a novel thiosemicarbazone derivative in human leukemia and lymphoma cell lines
Published in Hematology/oncology and stem cell therapy (01-03-2021)“…The present study aimed to investigate the cytotoxic effect of 38 new thiosemicarbazone derivatives on hematological neoplastic cells lines and to select the…”
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The importance of CD39, CD43, CD81, and CD95 expression for differentiating B cell lymphoma by flow cytometry
Published in Cytometry. Part B, Clinical cytometry (01-05-2018)“…Background B cell lymphomas' (BCL) current diagnosis is usually based on a combination of morphology, immunophenotype, recurrent cytogenetic aberration and…”
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Mucormycosis causing oral and nasal osteonecrosis in a case of acute myeloid leukemia
Published in Special care in dentistry (01-09-2023)“…Mucormycosis is a rare and aggressive fungal infection with a high mortality rate because of its rapidly progressive and destructive nature. The oral cavity is…”
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Updating recommendations of the Brazilian Group of Flow Cytometry (GBCFLUX) for diagnosis of acute leukemias using four-color flow cytometry panels
Published in Hematology, Transfusion and Cell Therapy (01-10-2021)“…INTRODUCTIONFlow cytometry has become an increasingly important tool in the clinical laboratory for the diagnosis and monitoring of many hematopoietic…”
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Evaluation of CD307a expression patterns during normal B‐cell maturation and in B‐cell malignancies by flow cytometry
Published in Cytometry. Part B, Clinical cytometry (01-07-2018)“…Background Flow cytometric immunophenotyping is deemed a fundamental tool for the diagnosis of B‐cell neoplasms. Currently, the investigation of novel…”
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Apoptotic Events Induced by Maleimides on Human Acute Leukemia Cell Lines
Published in Chemical research in toxicology (16-12-2013)“…Cyclic imides are known for their antitumor activity, especially the naphthalimide derivatives, such as Mitonafide and Amonafide. Recently, we have…”
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Analysis of the presence of FLT3 gene mutation and association with prognostic factors in adult and pediatric acute leukemia patients
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2017)“…When the FLT3 gene is mutated, it originates a modified receptor with structural changes, which give survival advantage and malignant hematopoietic cell…”
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