Search Results - "Maria A Deli"

Glycocalyx regulates the strength and kinetics of cancer cell adhesion revealed by biophysical models based on high resolution label-free optical data by Kanyo, Nicolett, Kovacs, Kinga Dora, Saftics, Andras, Szekacs, Inna, Peter, Beatrix, Santa-Maria, Ana R., Walter, Fruzsina R., Dér, András, Deli, Mária A., Horvath, Robert

“…The glycocalyx is thought to perform a potent, but not yet defined function in cellular adhesion and signaling. Since 95% of cancer cells have altered…”
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Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model by Santa-Maria, Ana R, Walter, Fruzsina R, Figueiredo, Ricardo, Kincses, András, Vigh, Judit P, Heymans, Marjolein, Culot, Maxime, Winter, Peter, Gosselet, Fabien, Dér, András, Deli, Mária A

“…Microfluidic lab-on-a-chip (LOC) devices allow the study of blood-brain barrier (BBB) properties in dynamic conditions. We studied a BBB model, consisting of…”
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A versatile lab-on-a-chip tool for modeling biological barriers by Walter, Fruzsina R., Valkai, Sándor, Kincses, András, Petneházi, András, Czeller, Tamás, Veszelka, Szilvia, Ormos, Pál, Deli, Mária A., Dér, András

“…•Miniaturized microfluidic chip for biological barriers.•Integrating resistance, permeability and full microscopic monitoring.•Tested with various epithelial…”
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Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models by Hellinger, Éva, Veszelka, Szilvia, Tóth, Andrea E., Walter, Fruzsina, Kittel, Ágnes, Bakk, Mónika Laura, Tihanyi, Károly, Háda, Viktor, Nakagawa, Shinsuke, Dinh Ha Duy, Thuy, Niwa, Masami, Deli, Mária A., Vastag, Monika

“…Functional and morphological comparison of the primary endothelial triple co-culture blood–brain barrier (BBB) model, the high P-glycoprotein expressing…”
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Intracellular transport of Toxoplasma gondii through the blood–brain barrier by Lachenmaier, Sabrina M, Deli, Mária A, Meissner, Markus, Liesenfeld, Oliver

“…Abstract Toxoplasma gondii establishes latent infection in the central nervous system of immunocompentent hosts. Toxoplasmic encephalitis is a life threatening…”
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ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood-Brain Barrier by Topal, Gizem Rüya, Mészáros, Mária, Porkoláb, Gergő, Szecskó, Anikó, Polgár, Tamás Ferenc, Siklós, László, Deli, Mária A, Veszelka, Szilvia, Bozkir, Asuman

“…Pharmacological treatment of central nervous system (CNS) disorders is difficult, because the blood-brain barrier (BBB) restricts the penetration of many drugs…”
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17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier by Vágvölgyi, Máté, Laczkó, Dávid, Santa-Maria, Ana Raquel, Vigh, Judit P, Walter, Fruzsina R, Berkecz, Róbert, Deli, Mária A, Tóth, Gábor, Hunyadi, Attila

“…20-Hydroxyecdysone and several of its oxidized derivatives exert cytoprotective effect in mammals including humans. Inspired by this bioactivity of…”
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Transendothelial Electrical Resistance Measurement across the Blood–Brain Barrier: A Critical Review of Methods by Vigh, Judit P., Kincses, András, Ozgür, Burak, Walter, Fruzsina R., Santa-Maria, Ana Raquel, Valkai, Sándor, Vastag, Mónika, Neuhaus, Winfried, Brodin, Birger, Dér, András, Deli, Mária A.

“…The blood–brain barrier (BBB) represents the tightest endothelial barrier within the cardiovascular system characterized by very low ionic permeability. Our…”
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Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters by György, Bence, Módos, Károly, Pállinger, Éva, Pálóczi, Krisztina, Pásztói, Mária, Misják, Petra, Deli, Mária A., Sipos, Áron, Szalai, Anikó, Voszka, István, Polgár, Anna, Tóth, Kálmán, Csete, Mária, Nagy, György, Gay, Steffen, Falus, András, Kittel, Ágnes, Buzás, Edit I.

“…Numerous diseases, recently reported to associate with elevated microvesicle/microparticle (MP) counts, have also long been known to be characterized by…”
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In Vitro Comparative Study of Solid Lipid and PLGA Nanoparticles Designed to Facilitate Nose-to-Brain Delivery of Insulin by Akel, Hussein, Csóka, Ildikó, Ambrus, Rita, Bocsik, Alexandra, Gróf, Ilona, Mészáros, Mária, Szecskó, Anikó, Kozma, Gábor, Veszelka, Szilvia, Deli, Mária A, Kónya, Zoltán, Katona, Gábor

“…The brain insulin metabolism alteration has been addressed as a pathophysiological factor underlying Alzheimer's disease (AD). Insulin can be beneficial in AD,…”
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Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells by Kiss, Lóránd, Walter, Fruzsina R, Bocsik, Alexandra, Veszelka, Szilvia, Ozsvári, Béla, Puskás, László G, Szabó-Révész, Piroska, Deli, Mária A

“…Cremophor EL and RH40 are widely used excipients in oral and intravenous drug formulations such as Taxol infusion to improve drug dissolution and absorption…”
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Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats by Sántha, Petra, Veszelka, Szilvia, Hoyk, Zsófia, Mészáros, Mária, Walter, Fruzsina R, Tóth, Andrea E, Kiss, Lóránd, Kincses, András, Oláh, Zita, Seprényi, György, Rákhely, Gábor, Dér, András, Pákáski, Magdolna, Kálmán, János, Kittel, Ágnes, Deli, Mária A

“…Stress is well-known to contribute to the development of both neurological and psychiatric diseases. While the role of the blood-brain barrier is increasingly…”
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Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells by Cardoso, Filipa L, Kittel, Agnes, Veszelka, Szilvia, Palmela, Inês, Tóth, Andrea, Brites, Dora, Deli, Mária A, Brito, Maria A

“…Sepsis and jaundice are common conditions in newborns that can lead to brain damage. Though lipopolysaccharide (LPS) is known to alter the integrity of the…”
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Pericytes from brain microvessels strengthen the barrier integrity in primary cultures of rat brain endothelial cells by Nakagawa, Shinsuke, Deli, Mária A, Nakao, Shinobu, Honda, Masaru, Hayashi, Kentaro, Nakaoke, Ryota, Kataoka, Yasufumi, Niwa, Masami

“…(1) The blood-brain barrier (BBB) characteristics of cerebral endothelial cells are induced by organ-specific local signals. Brain endothelial cells lose their…”
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Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport by Veszelka, Szilvia, Tóth, András, Walter, Fruzsina R, Tóth, Andrea E, Gróf, Ilona, Mészáros, Mária, Bocsik, Alexandra, Hellinger, Éva, Vastag, Monika, Rákhely, Gábor, Deli, Mária A

“…Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain…”
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Edaravone protects against methylglyoxal-induced barrier damage in human brain endothelial cells by Tóth, Andrea E, Walter, Fruzsina R, Bocsik, Alexandra, Sántha, Petra, Veszelka, Szilvia, Nagy, Lajos, Puskás, László G, Couraud, Pierre-Olivier, Takata, Fuyuko, Dohgu, Shinya, Kataoka, Yasufumi, Deli, Mária A

“…Elevated level of reactive carbonyl species, such as methylglyoxal, triggers carbonyl stress and activates a series of inflammatory responses leading to…”
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Supermacroporous chemically cross-linked poly(aspartic acid) hydrogels by Gyarmati, Benjámin, Mészár, E. Zsuzsanna, Kiss, Lóránd, Deli, Mária A., László, Krisztina, Szilágyi, András

“…[Display omitted] Chemically cross-linked poly(aspartic acid) (PASP) gels were prepared by a solid–liquid phase separation technique, cryogelation, to achieve…”
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Low dose cranial irradiation-induced cerebrovascular damage is reversible in mice by Sándor, Nikolett, Walter, Fruzsina R, Bocsik, Alexandra, Sántha, Petra, Schilling-Tóth, Boglárka, Léner, Violetta, Varga, Zoltán, Kahán, Zsuzsanna, Deli, Mária A, Sáfrány, Géza, Hegyesi, Hargita

“…High-dose radiation-induced blood-brain barrier breakdown contributes to acute radiation toxicity syndrome and delayed brain injury, but there are few data on…”
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Effects of sub-chronic, in vivo administration of sigma-1 receptor ligands on platelet and aortic arachidonate cascade in streptozotocin-induced diabetic rats by Váczi, Sándor, Barna, Lilla, Laczi, Krisztián, Tömösi, Ferenc, Rákhely, Gábor, Penke, Botond, Fülöp, Lívia, Bogár, Ferenc, Janáky, Tamás, Deli, Mária A, Mezei, Zsófia

“…Diabetes mellitus is a chronic metabolic disorder which induces endothelial dysfunction and platelet activation. Eicosanoids produced from arachidonic acid…”
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Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors by Dvorácskó, Szabolcs, Keresztes, Attila, Mollica, Adriano, Stefanucci, Azzurra, Macedonio, Giorgia, Pieretti, Stefano, Zádor, Ferenc, Walter, Fruzsina R., Deli, Mária A., Kékesi, Gabriella, Bánki, László, Tuboly, Gábor, Horváth, Gyöngyi, Tömböly, Csaba

“…In order to obtain novel pharmacological tools and to investigate a multitargeting analgesic strategy, the CB1 and CB2 cannabinoid receptor agonist JWH-018 was…”
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