Search Results - "Margulis, B"

Ectopic BH3-Only Protein Bim Associates with Hsp70 to Regulate Yeast Mitophagy by Yuan, Linjie, Wang, Yuying, Margulis, B. A., Song, Ting, Wang, Ziqian, Zhang, Zhichao

“…Mitophagy, a form of selective autophagy, plays an essential role to maintain a population of healthy and functional mitochondria for normal cellular…”
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The Effect of HSF1 Activity Inhibitor of the Cardenolide Group (CL-43) on Tumor and Nontransformed Cells by Vladimirova, S. A., Margulis, B. A., Guzhova, I. V., Nicotina, A. D.

“…The occurrence of intolerable side effects in patients undergoing chemotherapy continues to be a key clinical obstacle. In this regard, the search for…”
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Suppression of the Expression of Molecular Chaperones as a Factor in Increasing the Efficiency of Antitumor Therapy by Mikeladze, M. A., Mikhailova, E. R., Margulis, B. A., Guzhova, I. V.

“…Modern methods of antitumor chemotherapy are not able to destroy 100% of the cell population. The use of modern methods of chemotherapy is constrained by the…”
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Inhibition of biofilm formation in Bacillus subtilis by new halogenated furanones by Kayumov, Airat R, Khakimullina, Elvina N, Sharafutdinov, Irshad S, Trizna, Elena Y, Latypova, Lilia Z, Thi Lien, Hoang, Margulis, Anna B, Bogachev, Mikhail I, Kurbangalieva, Almira R

“…Gram-positive bacteria can cause various infections including hospital-acquired infections. While in the biofilm, the resistance of bacteria to both…”
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Distribution of Metastases in the Organs of Mice after Orthotopic Injection of CT26 Colorectal Cancer Cells by Kuznetsova, L. S., Margulis, B. A., Guzhova, I. V., Lazarev, V. F.

“…One reason for the high mortality rate from bowel cancer is the formation of metastases, and effective animal models of cancer are needed to analyze the…”
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On the theoretical foundations and historical development of radical Islam as a political ideology by Margulis, Sergey B.

“…The purpose of this article is the analysis of the theoretical foundations of radical Islamism as a political ideology and consideration of the main historical…”
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Dynamics of the Functional Activity and Expression of Proteasome Subunits during Cellular Adaptation to Heat Shock by Morozov, A. V., Burov, A. V., Astakhova, T. M., Spasskaya, D. S., Margulis, B. A., Karpov, V. L.

“…The ubiquitin-proteasome system (UPS) performs proteolysis of most intracellular proteins. The key components of the UPS are the proteasomes, multi-subunit…”
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2929 Superparamagnetic nanoparticles conjugated with 70-kDa heat shock protein (SPION-Hsp70) as a theranostic platform in neuro-oncology by Shevtsov, M, Nikolaev, B, Yakovleva, L, Marchenko, Y, Pitkin, E, Dobrodumov, A, Margulis, B, Guzhova, I

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Indolyl- and Pyrrolylazine Derivatives Cause the Accumulation of Heat Shock Protein Hsp70 in Sh-Sy5Y Human Neuroblastoma Cells by Lazarev, V. F., Mikhaylova, E. R., Mikeladze, M. A., Trestsova, M. A., Utepova, I. A., Chupakhin, O. N., Margulis, B. A., Guzhova, I. V.

“…The heat shock protein Hsp70 is involved in cell defense from various types of stress, including the proteotoxic stress, which occurs during the development of…”
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CL-43, a New Inhibitor of HSF1 Activity, Inhibits Epithelial-Mesenchymal Transition of DLD1 Colon Cancer Cells by Nikotina, A. D., Kartsev, V. G., Margulis, B. A., Guzhova, I. V.

“…Colorectal cancer is highly metastatic. In a quarter of patients with tumors of this type, liver metastases are detected already at the time of diagnosis…”
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P56 by Meshalkina, D, Shevtsov, M, Margulis, B, Guzhova, I

“…Glioblastoma is one of the most malignant cancer types. Its median survival is 15 months with combined radio- and chemotherapy and only 4 months without…”
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The Spread of the Post-Industrial Islamism in the Russian Federation by Demidenko, Sergey V., Margulis, Sergey B., Fainshmidt, Roman I.

“…Radical Islam as a political phenomenon has undergone significant changes during the first decades of the 21st century. This process was accompanied, firstly,…”
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Testing a Novel Heat-Shock Protein Inducer in the Cellular Model of Traumatic Brain Injury Response by Lazarev, V. F., Dutysheva, E. A., Trestsova, M. A., Mikeladze, M. A., Utepova, I. A., Chupakhin, O. N., Guzhova, I. V., Margulis, B. A.

“…— Traumatic brain injury (TBI) induces multiple pathological processes affecting various brain cells. the accumulation of toxic factors in interstitial and…”
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P74 by Guzhova, I, Shevtsov, M, Komarova, E, Meshalkina, D, Kisel, E, Margulis, B

“…The Hsp70 chaperone is one of the major components of tumor microenvironment displaying multiple not yet established functions. It was shown to stimulate…”
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Phenotypic Characteristics of Macrophages and Tumor Cells in Coculture by Marchenko, L. V., Nikotina, A. D., Aksenov, N. D., Smagina, L. V., Margulis, B. A., Guzhova, I. V.

“…— Immunosuppressive activity of a tumor is provided by constituents of its microenvironment (TME), immune cells, particularly macrophages, which, instead of…”
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PO-411 Combinatorial therapy with immune checkpoint blockade and theranostic tumor-targeted nanoparticles in eradication of tumours by Shevtsov, M, Stangl, S, Pitkin, E, Nikolaev, B, Marchenko, Y, Yakovleva, L, Ryzhov, V, Margulis, B, Guzhova, I, Multhoff, G

“…IntroductionTargeted superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as a promising detection tool for the molecular magnetic resonance…”
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Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis by Lazarev, V F, Sverchinskyi, D V, Ippolitova, M V, Stepanova, A V, Guzhova, I V, Margulis, B A

“…Most neurodegenerative pathologies stem from the formation of aggregates of mutant proteins, causing dysfunction and ultimately neuronal death. This study was…”
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Kinetics of chaperone activity of proteins Hsp70 and Hdj1 in human leukemia U-937 cells after preconditioning with thermal shock or compound U-133 by Lazarev, V. F., Onokhin, K. V., Antimonova, O. I., Polonik, S. G., Guzhova, I. V., Margulis, B. A.

“…Kinetics of the chaperone activity of proteins Hsp70 and Hdj1 were analyzed in human U-937 promonocytes during their response to heat shock or to treatment…”
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Heat stress stimulates colon cancer cells to secret specific population of extracellular nanovesicles enriched by HSP70 and microRNAs by Nazarova, I. V., Zabegina, L. M., Nikiforova, N. S., Slusarenko, M. A., Sidina, E. I., Zhakhov, A. V., Ishchenko, A. M., Margulis, B. A., Guzhova, I. V., Malek, A. V.

“…Background. Heat stress (HS) induces the cellular secretion of heat shock proteins (HSP ) and extracellular nanovesicles (ENVs). The biological link between…”
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Stress response in Baikalian sponges exposed to pollutants by Schröder, H. C., Efremova, S. M., Margulis, B. A., Guzhova, I. V., Itskovich, V. B., Müller, W. E. G.

“…Issue Title: Theme:Species and Speciation in Ancient Lakes In a first biomarker-based study in Lake Baikal, we demonstrated that the heat shock protein Hsp70,…”
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