Search Results - "Margolis, L"

Self-Measured Blood Pressure Monitoring at Home: A Joint Policy Statement From the American Heart Association and American Medical Association by Shimbo, Daichi, Artinian, Nancy T., Basile, Jan N., Krakoff, Lawrence R., Margolis, Karen L., Rakotz, Michael K., Wozniak, Gregory

“…The diagnosis and management of hypertension, a common cardiovascular risk factor among the general population, have been based primarily on the measurement of…”
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Self-monitoring of blood pressure in hypertension: A systematic review and individual patient data meta-analysis by Tucker, Katherine L, Sheppard, James P, Stevens, Richard, Bosworth, Hayden B, Bove, Alfred, Bray, Emma P, Earle, Kenneth, George, Johnson, Godwin, Marshall, Green, Beverly B, Hebert, Paul, Hobbs, F D Richard, Kantola, Ilkka, Kerry, Sally M, Leiva, Alfonso, Magid, David J, Mant, Jonathan, Margolis, Karen L, McKinstry, Brian, McLaughlin, Mary Ann, Omboni, Stefano, Ogedegbe, Olugbenga, Parati, Gianfranco, Qamar, Nashat, Tabaei, Bahman P, Varis, Juha, Verberk, Willem J, Wakefield, Bonnie J, McManus, Richard J

“…Self-monitoring of blood pressure (BP) appears to reduce BP in hypertension but important questions remain regarding effective implementation and which groups…”
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Effect of Aspirin on Disability-free Survival in the Healthy Elderly by McNeil, John J, Woods, Robyn L, Nelson, Mark R, Reid, Christopher M, Kirpach, Brenda, Wolfe, Rory, Storey, Elsdon, Shah, Raj C, Lockery, Jessica E, Tonkin, Andrew M, Newman, Anne B, Williamson, Jeff D, Margolis, Karen L, Ernst, Michael E, Abhayaratna, Walter P, Stocks, Nigel, Fitzgerald, Sharyn M, Orchard, Suzanne G, Trevaks, Ruth E, Beilin, Lawrence J, Donnan, Geoffrey A, Gibbs, Peter, Johnston, Colin I, Ryan, Joanne, Radziszewska, Barbara, Grimm, Richard, Murray, Anne M

“…In a trial comparing 100 mg of aspirin with placebo in nearly 20,000 community-dwelling persons 70 years of age or older in Australia and the United States,…”
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Effect of Aspirin on All-Cause Mortality in the Healthy Elderly by McNeil, John J, Nelson, Mark R, Woods, Robyn L, Lockery, Jessica E, Wolfe, Rory, Reid, Christopher M, Kirpach, Brenda, Shah, Raj C, Ives, Diane G, Storey, Elsdon, Ryan, Joanne, Tonkin, Andrew M, Newman, Anne B, Williamson, Jeff D, Margolis, Karen L, Ernst, Michael E, Abhayaratna, Walter P, Stocks, Nigel, Fitzgerald, Sharyn M, Orchard, Suzanne G, Trevaks, Ruth E, Beilin, Lawrence J, Donnan, Geoffrey A, Gibbs, Peter, Johnston, Colin I, Radziszewska, Barbara, Grimm, Richard, Murray, Anne M

“…After a median follow-up of 4.7 years, there were 1.6 more deaths per 1000 person-years among healthy older adults who were randomly assigned to receive…”
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Use of single guided Cas9 nickase to facilitate precise and efficient genome editing in human iPSCs by Li, Pan P., Margolis, Russell L.

“…Cas9 nucleases permit rapid and efficient generation of gene-edited cell lines. However, in typical protocols, mutations are intentionally introduced into the…”
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Incidence and Prognosis of Resistant Hypertension in Hypertensive Patients by DAUGHERTY, Stacie L, POWERS, J. David, MAGID, David J, TAVEL, Heather M, MASOUDI, Frederick A, MARGOLIS, Karen L, O'CONNOR, Patrick J, SELBY, Joe V, MICHAEL HO, P

“…Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, the incidence and prognosis of this…”
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Synaptic dysregulation in a human iPS cell model of mental disorders by Wen, Zhexing, Nguyen, Ha Nam, Guo, Ziyuan, Lalli, Matthew A., Wang, Xinyuan, Su, Yijing, Kim, Nam-Shik, Yoon, Ki-Jun, Shin, Jaehoon, Zhang, Ce, Makri, Georgia, Nauen, David, Yu, Huimei, Guzman, Elmer, Chiang, Cheng-Hsuan, Yoritomo, Nadine, Kaibuchi, Kozo, Zou, Jizhong, Christian, Kimberly M., Cheng, Linzhao, Ross, Christopher A., Margolis, Russell L., Chen, Gong, Kosik, Kenneth S., Song, Hongjun, Ming, Guo-li

“…Generation and neural differentiation of induced pluripotent stem cells (iPS cells) from patients enables new ways to investigate the cellular pathophysiology…”
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Huntington disease: natural history, biomarkers and prospects for therapeutics by Ross, Christopher A., Aylward, Elizabeth H., Wild, Edward J., Langbehn, Douglas R., Long, Jeffrey D., Warner, John H., Scahill, Rachael I., Leavitt, Blair R., Stout, Julie C., Paulsen, Jane S., Reilmann, Ralf, Unschuld, Paul G., Wexler, Alice, Margolis, Russell L., Tabrizi, Sarah J.

“…Key Points No disease-modifying treatments are currently available for Huntington disease (HD), but clinical trials of potential compounds are imminent;…”
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Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women’s Health Initiative Randomized Trials by Manson, JoAnn E, Chlebowski, Rowan T, Stefanick, Marcia L, Aragaki, Aaron K, Rossouw, Jacques E, Prentice, Ross L, Anderson, Garnet, Howard, Barbara V, Thomson, Cynthia A, LaCroix, Andrea Z, Wactawski-Wende, Jean, Jackson, Rebecca D, Limacher, Marian, Margolis, Karen L, Wassertheil-Smoller, Sylvia, Beresford, Shirley A, Cauley, Jane A, Eaton, Charles B, Gass, Margery, Hsia, Judith, Johnson, Karen C, Kooperberg, Charles, Kuller, Lewis H, Lewis, Cora E, Liu, Simin, Martin, Lisa W, Ockene, Judith K, O’Sullivan, Mary Jo, Powell, Lynda H, Simon, Michael S, Van Horn, Linda, Vitolins, Mara Z, Wallace, Robert B

“…IMPORTANCE Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention. OBJECTIVE…”
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Association between diabetes, diabetes treatment and risk of developing endometrial cancer by Luo, J, Beresford, S, Chen, C, Chlebowski, R, Garcia, L, Kuller, L, Regier, M, Wactawski-Wende, J, Margolis, K L

“…Background: A growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used…”
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RAN Translation in Huntington Disease by Bañez-Coronel, Monica, Ayhan, Fatma, Tarabochia, Alex D, Zu, Tao, Perez, Barbara A, Tusi, Solaleh Khoramian, Pletnikova, Olga, Borchelt, David R, Ross, Christopher A, Margolis, Russell L, Yachnis, Anthony T, Troncoso, Juan C, Ranum, Laura P W

“…Huntington disease (HD) is caused by a CAG ⋅ CTG expansion in the huntingtin (HTT) gene. While most research has focused on the HTT polyGln-expansion protein,…”
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Pre-existing diabetes and lung cancer prognosis by Luo, Juhua, Hendryx, Michael, Qi, Lihong, Ho, Gloria YF, Margolis, Karen L

“…Background: The aims of this study are to investigate the impact of pre-existing diabetes and diabetes treatments on lung cancer prognosis. Methods: A total of…”
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Intentional Weight Loss and Endometrial Cancer Risk by Luo, Juhua, Chlebowski, Rowan T, Hendryx, Michael, Rohan, Thomas, Wactawski-Wende, Jean, Thomson, Cynthia A, Felix, Ashley S, Chen, Chu, Barrington, Wendy, Coday, Mace, Stefanick, Marcia, LeBlanc, Erin, Margolis, Karen L

“…Purpose Although obesity is an established endometrial cancer risk factor, information about the influence of weight loss on endometrial cancer risk in…”
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Outcomes of Combined Cardiovascular Risk Factor Management Strategies in Type 2 Diabetes: The ACCORD Randomized Trial by MARGOLIS, Karen L, O'CONNOR, Patrick J, LIPKIN, Edward W, NARAYAN, K. M. Venkat, RIDDLE, Matthew C, SOOD, Ajay, GOFF, David C, MORGAN, Timothy M, BUSE, John B, COHEN, Robert M, CUSHMAN, William C, CUTLER, Jeffrey A, EVANS, Gregory W, GERSTEIN, Hertzel C, GRIMM, Richard H

“…To compare effects of combinations of standard and intensive treatment of glycemia and either blood pressure (BP) or lipids in the Action to Control…”
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Epidemiologic Relationships Between A1C and All-Cause Mortality During a Median 3.4-Year Follow-up of Glycemic Treatment in the ACCORD Trial by RIDDLE, MatthewC, AMBROSIUS, Walter T, SCHNALL, Adrian, SEAQUIST, Elizabeth R, BRILLON, David J, BUSE, John B, BYINGTON, Robert P, COHEN, Robert M, GOFF, David C, MALOZOWSKI, Saul, MARGOLIS, Karen L, PROBSTFIELD, Jeffrey L

“…Randomized treatment comparing an intensive glycemic treatment strategy with a standard strategy in the Action to Control Cardiovascular Risk in Diabetes…”
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Change in Weight Status and Development of Hypertension by Parker, Emily D, Sinaiko, Alan R, Kharbanda, Elyse O, Margolis, Karen L, Daley, Matt F, Trower, Nicole K, Sherwood, Nancy E, Greenspan, Louise C, Lo, Joan C, Magid, David J, O'Connor, Patrick J

“…To examine the association of BMI percentile and change in BMI percentile to change in blood pressure (BP) percentile and development of hypertension (HTN)…”
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Identification of a B cell signature associated with renal transplant tolerance in humans by Newell, Kenneth A, Asare, Adam, Kirk, Allan D, Gisler, Trang D, Bourcier, Kasia, Suthanthiran, Manikkam, Burlingham, William J, Marks, William H, Sanz, Ignacio, Lechler, Robert I, Hernandez-Fuentes, Maria P, Turka, Laurence A, Seyfert-Margolis, Vicki L

“…Establishing long-term allograft acceptance without the requirement for continuous immunosuppression, a condition known as allograft tolerance, is a highly…”
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An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice by Wilburn, Brian, Rudnicki, Dobrila D., Zhao, Jing, Weitz, Tara Murphy, Cheng, Yin, Gu, Xiaofeng, Greiner, Erin, Park, Chang Sin, Wang, Nan, Sopher, Bryce L., La Spada, Albert R., Osmand, Alex, Margolis, Russell L., Sun, Yi E., Yang, X. William

“…Huntington's disease-like-2 (HDL2) is a phenocopy of Huntington's disease caused by CTG/CAG repeat expansion at the Junctophilin-3 (JPH3) locus. The mechanisms…”
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Early Patient-Centered Outcomes Research Experience With the Use of Telehealth to Address Disparities: Scoping Review by Bailey, James E, Gurgol, Cathy, Pan, Eric, Njie, Shirilyn, Emmett, Susan, Gatwood, Justin, Gauthier, Lynne, Rosas, Lisa G, Kearney, Shannon M, Robler, Samantha Kleindienst, Lawrence, Raymona H, Margolis, Karen L, Osunkwo, Ifeyinwa, Wilfley, Denise, Shah, Vallabh O

“…Health systems and providers across America are increasingly employing telehealth technologies to better serve medically underserved low-income, minority, and…”
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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells by Juopperi, Tarja A, Kim, Woon Ryoung, Chiang, Cheng-Hsuan, Yu, Huimei, Margolis, Russell L, Ross, Christopher A, Ming, Guo-li, Song, Hongjun

“…Huntington's Disease (HD) is a devastating neurodegenerative disorder that clinically manifests as motor dysfunction, cognitive impairment and psychiatric…”
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