Search Results - "Margareth Fátima Formiga Melo Diniz"
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Anti-inflammatory activity of alkaloids: an update from 2000 to 2010
Published in Molecules (11-10-2011)“…Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced…”
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2
Computer-Aided Drug Design Using Sesquiterpene Lactones as Sources of New Structures with Potential Activity against Infectious Neglected Diseases
Published in Molecules (Basel, Switzerland) (03-01-2017)“…This review presents an survey to the biological importance of sesquiterpene lactones (SLs) in the fight against four infectious neglected tropical diseases…”
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3
Maytenus erythroxylon Reissek(Celastraceae) ethanol extract presents antidiarrheal activity via antimotility and antisecretory mechanisms
Published in World journal of gastroenterology : WJG (28-06-2017)“…AIM To investigate the acute toxicity,phytochemical profile,antidiarrheal activity and mechanisms of action of Maytenus erythroxylon(M.erythroxylon)ethanol…”
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4
New Therapeutic Targets and Drugs for the Treatment of Asthma
Published in Mini reviews in medicinal chemistry (01-01-2018)“…Asthma is an inflammatory disease which affects millions of people worldwide. Therefore, it is necessary to search for new sources of therapies for the…”
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Computational Chemistry Study of Natural Alkaloids and Homemade Databank to Predict Inhibitory Potential Against Key Enzymes in Neurodegenerative Diseases
Published in Current topics in medicinal chemistry (01-01-2017)“…Cissampelos sympodialis Eichl is used in folk medicine for the treatment of various inflammatory diseases; several alkaloids have been isolated from this…”
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Gastric and duodenal antiulcer activity of alkaloids: a review
Published in Molecules (17-12-2008)“…Peptic ulcer disease is a deep gastrointestinal erosion disorder that involves the entire mucosal thickness and can even penetrate the muscular mucosa…”
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7
Medicinal Plants and Other Living Organisms with Antitumor Potential against Lung Cancer
Published in Evidence-based complementary and alternative medicine (01-01-2014)“…Lung cancer is a disease with high morbidity and mortality rates. As a result, it is often associated with a significant amount of suffering and a general…”
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8
Isopropyl Caffeate: A Caffeic Acid Derivative—Antioxidant Potential and Toxicity
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Phenolic compounds, among them isopropyl caffeate, possess antioxidant potential, but not without toxicity and/or adverse effects. The present study aimed to…”
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Activity of alkaloids on peptic ulcer: what's new?
Published in Molecules (08-01-2015)“…Peptic ulcer is a common disease characterized by lesions that affect the mucosa of the esophagus, stomach and/or duodenum, and may extend into the muscular…”
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10
Azaphenanthrene alkaloids with antitumoral activity from Anaxagorea dolichocarpa Sprague & Sandwith (Annonaceae)
Published in Molecules (Basel, Switzerland) (22-08-2011)“…Phytochemical investigation of Anaxagorea dolichocarpa Sprague & Sandwith led to isolation of three azaphenanthrene alkaloids: eupolauramine, sampangine and…”
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11
Antifungal activity and mode of action of carvacrol against Candida albicans strains
Published in The Journal of essential oil research (01-04-2013)“…In this study, the minimal inhibitory concentration (MIC), minimal fungicidal concentration (MFC) and mode of action of carvacrol were determined. MIC was…”
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12
Traditional Uses, Chemical Constituents, and Biological Activities of Bixa orellana L.: A Review
Published in TheScientificWorld (01-01-2014)“…Bixa orellana L., popularly known as “urucum,” has been used by indigenous communities in Brazil and other tropical countries for several biological…”
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13
In Silico Study and Bioprospection of the Antibacterial and Antioxidant Effects of Flavone and Its Hydroxylated Derivatives
Published in Molecules (Basel, Switzerland) (24-05-2017)“…Flavonoid compounds are widely used as natural protective species, which can act as anti-inflammatory, antioxidant, anticoagulant, antihypertensive and…”
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14
Anxiolytic Effect of Citrus aurantium L. in Crack Users
Published in Evidence-based complementary and alternative medicine (01-01-2017)“…The objective of this study was to investigate the anxiolytic effects of the essential oil (EO) of Citrus aurantium L. in patients experiencing crack…”
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15
Matrix effect and optimization of LC–MSn determination of trachylobane-360 in mice blood
Published in Journal of pharmaceutical and biomedical analysis (01-11-2014)“…•Bioanalytical method for trachylobane-360.•Centrifugation, time and the extraction solvent used for liquid–liquid extraction.•Recovery optimization for…”
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16
Non-clinical acute and chronic toxicity evaluations of Cissus sicyoides L. (Vitaceae) hydroalcoholic leaf extract
Published in Toxicology reports (01-01-2018)“…[Display omitted] •The Cissus sicyoides species has several pharmacological activities.•The ethanolic extract from the leaves of Cissus caused few blood…”
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17
Clinical safety evaluation of a tea containing Cissampelos sympodialis in healthy volunteers
Published in Revista brasileira de farmacognosia (01-09-2015)“…Chromatographic profile (2D and 3D) the infusion of the leaves of Cissampelos sympodialis. Cissampelos sympodialis Eichler, Menispermaceae, is widely used by…”
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18
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate
Published in Drug and chemical toxicology (New York, N.Y. 1978) (04-07-2022)“…By submitting this manuscript, each author certifies that they have made a direct and substantial contribution to the work reported in the manuscript. In this…”
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Ultrastructural study on the morphological changes to male worms of Schistosoma mansoni after in vitro exposure to allicin
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-05-2011)“…Garlic has a wide range of actions, including antibacterial, antiviral, antifungal, antiprotozoal and anthelmintic actions. This antiparasitic activity has…”
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Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats
Published in BioMed research international (01-01-2013)“…The treatment during the embryonic preimplantation phase of Wistar rats with the Pradosia huberi extract did not interfere with the water and feed consumption,…”
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