Search Results - "Margalit, Danielle N"

Reirradiation for Head and Neck Cancer: The Who and the How by Margalit, Danielle N., Wong, Stuart J.

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The Benefits of Adjuvant Trastuzumab for HER‐2‐Positive Salivary Gland Cancers by Hanna, Glenn J., Bae, Ji Eun, Lorch, Jochen H., Haddad, Robert I., Jo, Vickie Y., Schoenfeld, Jonathan D., Margalit, Danielle N., Tishler, Roy B., Goguen, Laura A., Annino, Donald J., Chau, Nicole G.

“…Background Although high‐grade salivary gland cancers (SGCs) often express androgen receptor (AR) and/or HER‐2/neu, therapeutically targeting these receptors…”
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Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer by Sridharan, Vishwajith, Margalit, Danielle N, Lynch, Stephanie A, Severgnini, Mariano, Zhou, Jun, Chau, Nicole G, Rabinowits, Guilherme, Lorch, Jochen H, Hammerman, Peter S, Hodi, F Stephen, Haddad, Robert I, Tishler, Roy B, Schoenfeld, Jonathan D

“…Background: Preclinical and clinical studies suggest potential synergy between high dose per fraction focal radiation and immunotherapy. However,…”
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Long-term outcomes and clinicogenomic correlates in recurrent, metastatic adenoid cystic carcinoma by Hanna, Glenn J., Bae, Ji Eun, Lorch, Jochen H., Schoenfeld, Jonathan D., Margalit, Danielle N., Tishler, Roy B., Haddad, Robert I., Chau, Nicole G.

“…•ACC patients treated within 3 years of recurrent, metastatic diagnosis have poor outcomes.•Disease biology drives prognosis in ACC, despite the use of…”
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The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana‐Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline by Sultan, Ahmed, Hanna, Glenn J., Margalit, Danielle N., Chau, Nicole, Goguen, Laura A., Marty, Francisco M., Rabinowits, Guilherme, Schoenfeld, Jonathan D., Sonis, Stephen T., Thomas, Tom, Tishler, Roy B., Treister, Nathaniel S., Villa, Alessandro, Woo, Sook‐Bin, Haddad, Robert, Mawardi, Hani

“…Background Osteoradionecrosis of the jaw (ORN) is an infrequent yet potentially devastating complication of radiation therapy to the head and neck region…”
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Comparative Analysis of MicroRNA Expression among Benign and Malignant Tongue Tissue and Plasma of Patients with Tongue Cancer by Rabinowits, Guilherme, Bowden, Michaela, Flores, Ludmila M, Verselis, Sigitas, Vergara, Victoria, Jo, Vickie Y, Chau, Nicole, Lorch, Jochen, Hammerman, Peter S, Thomas, Tom, Goguen, Laura A, Annino, Donald, Schoenfeld, Jonathan D, Margalit, Danielle N, Tishler, Roy B, Haddad, Robert I

“…Identification of a microRNA (miRNA) pattern to be used as a biomarker for HNSCC is challenging given the heterogeneity of the disease and different…”
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Tolerability of Combined Modality Therapy for Rectal Cancer in Elderly Patients Aged 75 Years and Older by Margalit, Danielle N., M.D., M.P.H, Mamon, Harvey J., M.D., Ph.D, Ancukiewicz, Marek, Ph.D, Kobayashi, Wendy, B.A, Ryan, David P., M.D, Blaszkowsky, Lawrence S., M.D, Clark, Jeffrey, M.D, Willett, Christopher G., M.D, Hong, Theodore S., M.D

“…Purpose To determine the rate of treatment deviations during combined modality therapy for rectal cancer in elderly patients aged 75 years and older. Methods…”
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Everolimus in Anaplastic Thyroid Cancer: A Case Series by Harris, Ethan J, Hanna, Glenn J, Chau, Nicole, Rabinowits, Guilherme, Haddad, Robert, Margalit, Danielle N, Schoenfeld, Jonathan, Tishler, Roy B, Barletta, Justine A, Nehs, Matthew, Janne, Pasi, Huang, Julian, Groden, Phillip, Kacew, Alec, Lorch, Jochen

“…Anaplastic thyroid cancer (ATC) is a very aggressive disease and accounts for over 50% of thyroid-cancer related deaths. mTOR inhibition has shown anti-tumor…”
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Microinvasive Breast Cancer: ER, PR, and HER-2/neu Status and Clinical Outcomes after Breast-Conserving Therapy or Mastectomy by Margalit, Danielle N., Sreedhara, Meera, Chen, Yu-Hui, Catalano, Paul J., Nguyen, Paul L., Golshan, Mehra, Overmoyer, Beth A., Harris, Jay R., Brock, Jane E.

“…Background Contemporary clinical outcomes of microinvasive breast cancer (MIBC), defined as no focus >1 mm, are not well characterized. We document the…”
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Targeting Cell Division: Small-Molecule Inhibitors of FtsZ GTPase Perturb Cytokinetic Ring Assembly and Induce Bacterial Lethality by Margalit, Danielle N., Romberg, Laura, Mets, Rebecca B., Hebert, Alan M., Mitchison, Timothy J., Kirschner, Marc W., RayChaudhuri, Debabrata

“…FtsZ, the ancestral homolog of eukaryotic tubulins, is a GTPase that assembles into a cytokinetic ring structure essential for cell division in prokaryotic…”
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Population-based validation of the recursive partitioning analysis-based staging system for oropharyngeal cancer by Keane, Florence K., Chen, Yu-Hui, Tishler, Roy B., Schoenfeld, Jonathan D., Haddad, Robert I., Goguen, Laura A., Catalano, Paul, Neville, Bridget A., Margalit, Danielle N.

“…Background The American Joint Committee on Cancer (AJCC) staging system does not adequately distinguish prognostic groups in the era of human papillomavirus…”
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Patterns of failure after reirradiation with intensity-modulated radiation therapy and the competing risk of out-of-field recurrences by Margalit, Danielle N., MD MPH, Rawal, Bhupendra, MS, Catalano, Paul J., ScD, Haddad, Robert I., MD, Goguen, Laura A., MD, Annino, Donald J., MD DMD, Limaye, Sewanti A., MD MS, Lorch, Jochen H., MD MS, Lavigne, Annie W, Schoenfeld, Jonathan D., MD MPH, Sher, David J., MD, Tishler, Roy B., MD PhD

“…Highlights • Patterns of failure differ when reirradiation is definitive versus postoperative. • After definitive reirradiation, in-field failure is the most…”
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Radiation Oncology—New Approaches in Squamous Cell Cancer of the Head and Neck by Margalit, Danielle N., MD, MPH, Schoenfeld, Jonathon D., MD, MPH, Tishler, Roy B., MD, PhD

“…The many advances in radiotherapy for squamous cell cancer of the head and neck described in this article will have significant effects on the ultimate…”
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Active Tobacco Smoking and Distant Metastasis in Patients With Oropharyngeal Cancer by McBride, Sean M., M.D, Ali, Nawal N., B.S, Margalit, Danielle N., M.D., M.P.H, Chan, Annie W., M.D

“…Purpose Distant metastasis is the site of first relapse in approximately one-third of patients with locally advanced oropharyngeal carcinoma, irrespective of…”
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Technological Advancements and Error Rates in Radiation Therapy Delivery by Margalit, Danielle N., M.D. M.P.H, Chen, Yu-Hui, M.S., M.P.H, Catalano, Paul J., Sc.D, Heckman, Kenneth, B.S.N, Vivenzio, Todd, R.T.T, Nissen, Kristopher, R.T.T, Wolfsberger, Luciant D., M.S, Cormack, Robert A., Ph.D, Mauch, Peter, M.D, Ng, Andrea K., M.D., M.P.H

“…Purpose Technological advances in radiation therapy (RT) delivery have the potential to reduce errors via increased automation and built-in quality assurance…”
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The Touchy Topic of the Touch Cell: A Case of Merkel Cell Carcinoma by Margalit, Danielle N.

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Head and Neck Cancer Clinical Research on ClinicalTrials.gov: An Opportunity for Radiation Oncologists by Muralidhar, Vinayak, Giacalone, Nicholas J., Milani, Nastaran, Schoenfeld, Jonathan D., Tishler, Roy B., Rawal, Bhupendra, Margalit, Danielle N.

“…Many improvements in head and neck cancer (HNC) outcomes are related to optimization of radiation therapy (RT) dose, fractionation, normal-tissue sparing, and…”
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Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians' Health Study by Margalit, Danielle N., M.D., M.P.H, Kasperzyk, Julie L., Sc.D, Martin, Neil E., M.D., M.P.H, Sesso, Howard D., Sc.D., M.P.H, Gaziano, John Michael, M.D., M.P.H, Ma, Jing, M.D., Ph.D, Stampfer, Meir J., M.D., Dr.P.H, Mucci, Lorelei A., Sc.D., M.P.H

“…Purpose The safety of antioxidant supplementation during radiation therapy (RT) for cancer is controversial. Antioxidants could potentially counteract the…”
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Incidence and Demographic Burden of HPV-Associated Oropharyngeal Head and Neck Cancers in the United States by Mahal, Brandon A, Catalano, Paul J, Haddad, Robert I, Hanna, Glenn J, Kass, Jason I, Schoenfeld, Jonathan D, Tishler, Roy B, Margalit, Danielle N

“…Human papillomavirus (HPV)-positive oropharyngeal head and neck squamous cell carcinoma (OPSCC) is increasing in the United States. Current epidemiologic…”
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A comparative study of standard intensity-modulated radiotherapy and RapidArc planning techniques for ipsilateral and bilateral head and neck irradiation by Pursley, Jennifer, Ph.D, Damato, Antonio L., Ph.D, Czerminska, Maria A., M.S, Margalit, Danielle N., M.D., M.P.H, Sher, David J., M.D., M.P.H, Tishler, Roy B., M.D., Ph.D

“…Abstract The purpose of this study was to investigate class solutions using RapidArc volumetric-modulated arc therapy (VMAT) planning for ipsilateral and…”
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