Search Results - "Marfil‐Garza, Braulio A."

Clinical islet transplantation: Current progress and new frontiers by Marfil‐Garza, Braulio A., Shapiro, Andrew Mark James, Kin, Tatsuya

“…Islet transplantation (IT) is now a robust treatment for selected patients with type 1 diabetes suffering from recurrent hypoglycemia and impaired awareness of…”
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Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) agonists in islet transplantation: Endogenous in vivo regulatory T cell expansion promotes prolonged allograft survival by Marfil‐Garza, Braulio A., Pawlick, Rena L., Szeto, Jake, Kroger, Charles, Tahiliani, Vikas, Hefler, Joshua, Dadheech, Nidheesh, Seavey, Mathew M., Wolf, Jeffrey, Jasuja, Rahul R., James Shapiro, A. M.

“…Regulatory T cells (Tregs) modulate alloimmune responses and may facilitate minimization or withdrawal of immunosuppression posttransplant. Current approaches,…”
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Total pancreatectomy with islet cell autotransplantation in a 2‐year‐old child with hereditary pancreatitis due to a PRSS1 mutation by Marfil‐Garza, Braulio A., Hefler, Joshua, Dajani, Khaled, Kin, Tatsuya, James Shapiro, A. M.

“…Acute recurrent and chronic pancreatitis in children carries high morbidity and burden. Compared to adults, ~75% of the cases of chronic pancreatitis in…”
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Risk factors associated with prolonged hospital length-of-stay: 18-year retrospective study of hospitalizations in a tertiary healthcare center in Mexico by Marfil-Garza, Braulio A, Belaunzarán-Zamudio, Pablo F, Gulias-Herrero, Alfonso, Zuñiga, Antonio Camiro, Caro-Vega, Yanink, Kershenobich-Stalnikowitz, David, Sifuentes-Osornio, José

“…Hospital length-of-Stay has been traditionally used as a surrogate to evaluate healthcare efficiency, as well as hospital resource utilization. Prolonged…”
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A predictive computational platform for optimizing the design of bioartificial pancreas devices by Ernst, Alexander U., Wang, Long-Hai, Worland, Scott C., Marfil-Garza, Braulio A., Wang, Xi, Liu, Wanjun, Chiu, Alan, Kin, Tatsuya, O’Gorman, Doug, Steinschneider, Scott, Datta, Ashim K., Papas, Klearchos K., James Shapiro, A. M., Ma, Minglin

“…The delivery of encapsulated islets or stem cell-derived insulin-producing cells (i.e., bioartificial pancreas devices) may achieve a functional cure for type…”
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Mitochondrial regulation in human pluripotent stem cells during reprogramming and β cell differentiation by Jasra, Ila Tewari, Cuesta-Gomez, Nerea, Verhoeff, Kevin, Marfil-Garza, Braulio A., Dadheech, Nidheesh, Shapiro, A. M. James

“…Mitochondria are the powerhouse of the cell and dynamically control fundamental biological processes including cell reprogramming, pluripotency, and lineage…”
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Preclinical models of acute liver failure: a comprehensive review by Hefler, Joshua, Marfil-Garza, Braulio A, Pawlick, Rena L, Freed, Darren H, Karvellas, Constantine J, Bigam, David L, Shapiro, A M James

“…Acute liver failure is marked by the rapid deterioration of liver function in a previously well patient over period of days to weeks. Though relatively rare,…”
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Inducible Pluripotent Stem Cells as a Potential Cure for Diabetes by Verhoeff, Kevin, Henschke, Sarah J, Marfil-Garza, Braulio A, Dadheech, Nidheesh, Shapiro, Andrew Mark James

“…Over the last century, diabetes has been treated with subcutaneous insulin, a discovery that enabled patients to forego death from hyperglycemia. Despite novel…”
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Inactivation of SPAK kinase reduces body weight gain in mice fed a high-fat diet by improving energy expenditure and insulin sensitivity by Torre-Villalvazo, Ivan, Cervantes-Pérez, Luz Graciela, Noriega, Lilia G, Jiménez, Jose V, Uribe, Norma, Chávez-Canales, María, Tovar-Palacio, Claudia, Marfil-Garza, Braulio A, Torres, Nimbe, Bobadilla, Norma A, Tovar, Armando R, Gamba, Gerardo

“…The STE20/SPS1-related proline-alanine-rich protein kinase (SPAK) controls the activity of the electroneutral cation-chloride cotransporters (SLC12 family) and…”
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Evaluating Islet Cell Isolation and Transplantation From Donors Following Medical Assistance in Dying by Parente, Alessandro, Verhoeff, Kevin, Kin, Tatsuya, Hefler, Joshua, Marfil-Garza, Braulio A, Sanchez-Fernandez, Norberto, Lam, Anna, Lyon, James, O'Gorman, Doug, Dajani, Khaled Z, Anderson, Blaire L, Bigam, David L, MacDonald, Patrick E, Shapiro, A M James

“…Limited information is available regarding outcomes of islet cell isolation (ICI) and transplantation (ITx) using medical assistance in dying (MAiD) donors. We…”
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The low‐harm score for predicting mortality in patients diagnosed with COVID‐19: A multicentric validation study by Soto‐Mota, Adrian, Marfil‐Garza, Braulio A., Martínez Rodríguez, Erick, Barreto Rodríguez, José Omar, López Romo, Alicia Estela, Alberti Minutti, Paolo, Alejandre Loya, Juan Vicente, Pérez Talavera, Félix Emmanuel, Ávila Cervera, Freddy José, Velazquez Burciaga, Adriana, Morado Aramburo, Oscar, Piña Olguín, Luis Alberto, Soto‐Rodríguez, Adrian, Castañeda Prado, Andrés, Santillán Doherty, Patricio, O Galindo, Juan, Guízar García, Luis Alberto, Hernández Gordillo, Daniel, Gutiérrez Mejía, Juan

“…Objective We sought to determine the accuracy of the LOW‐HARM score (Lymphopenia, Oxygen saturation, White blood cells, Hypertension, Age, Renal injury, and…”
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Pancreatic islet transplantation in type 1 diabetes: 20-year experience from a single-centre cohort in Canada by Marfil-Garza, Braulio A, Imes, Sharleen, Verhoeff, Kevin, Hefler, Joshua, Lam, Anna, Dajani, Khaled, Anderson, Blaire, O'Gorman, Doug, Kin, Tatsuya, Bigam, David, Senior, Peter A, Shapiro, A M James

“…Islet transplantation offers an effective treatment for selected people with type 1 diabetes and intractable hypoglycaemia. Long-term experience, however,…”
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Long-term outcomes after normothermic machine perfusion in liver transplantation—Experience at a single North American center by Hefler, Joshua, Leon-Izquierdo, Dayne, Marfil-Garza, Braulio A., Meeberg, Glenda, Verhoeff, Kevin, Anderson, Blaire, Dajani, Khaled, Bigam, David L., Shapiro, A.M. James

“…Normothermic machine perfusion (NMP) has emerged as a valuable tool in the preservation of liver allografts before transplantation. Randomized trials have…”
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Progress in Translational Regulatory T Cell Therapies for Type 1 Diabetes and Islet Transplantation by Marfil-Garza, Braulio A, Hefler, Joshua, Bermudez De Leon, Mario, Pawlick, Rena, Dadheech, Nidheesh, Shapiro, A M James

“…Abstract Regulatory T cells (Tregs) have become highly relevant in the pathophysiology and treatment of autoimmune diseases, such as type 1 diabetes (T1D). As…”
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Machine Perfusion of the Liver: Applications Beyond Transplantation by Hefler, Joshua, Marfil-Garza, Braulio A., Dadheech, Nidheesh, Shapiro, A.M. James

“…Machine perfusion (MP) is at the forefront of innovation in modern liver transplantation. Several approaches, mainly varying the temperature at which the graft…”
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Pancreas and Islet Transplantation: Comparative Outcome Analysis of a Single-centre Cohort Over 20-years by Marfil-Garza, Braulio A., Hefler, Joshua, Verhoeff, Kevin, Lam, Anna, Dajani, Khaled, Anderson, Blaire, O’Gorman, Doug, Kin, Tatsuya, Bello-Chavolla, Omar Yaxmehen, Grynoch, Donald, Halpin, Anne, Campbell, Patricia M., Senior, Peter A., Bigam, David, Shapiro, A.M. James

“…To provide the largest single-center analysis of islet (ITx) and pancreas (PTx) transplantation. Studies describing long-term outcomes with ITx and PTx are…”
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Outcomes Following Extrahepatic and Intraportal Pancreatic Islet Transplantation: A Comparative Cohort Study by Verhoeff, Kevin, Marfil-Garza, Braulio A., Sandha, Gurpal, Cooper, David, Dajani, Khaled, Bigam, David L., Anderson, Blaire, Kin, Tatsuya, Lam, Anna, O’Gorman, Doug, Senior, Peter A., Ricordi, Camillo, Shapiro, A.M. James

“…Preliminary studies show promise for extrahepatic islet transplantation (ITx). However, clinical comparisons with intraportal ITx outcomes remain limited. This…”
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336-OR: Females Undergoing Islet Transplantation with CNI-Based Immunosuppression May Be at Higher Risk of Renal Function Decline by CARR, ALICE L.J., MARFIL-GARZA, BRAULIO A., LAM, ANNA, ANDERSON, BLAIRE L., O'GORMAN, DOUG, KIN, TATSUYA, BIGAM, DAVID, JAMES SHAPIRO, A.M., SENIOR, PETER A.

“…Islet transplantation (ITx) is an established treatment for recurrent, severe hypoglycemia in type 1 diabetes, however, requires lifelong immunosuppression…”
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Stem Cell–Derived Islet Transplantation in Patients With Type 2 Diabetes: Can Diabetes Subtypes Guide Implementation? by Verhoeff, Kevin, Marfil-Garza, Braulio A, Czarnecka, Zofia, Cuesta-Gomez, Nerea, Jasra, Ila Tewari, Dadheech, Nidheesh, Senior, Peter A, Shapiro, A M James

“…Abstract Historically, only patients with brittle diabetes or severe recurrent hypoglycemia have been considered for islet transplantation (ITx). This…”
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Update on islet cell transplantation by Verhoeff, Kevin, Marfil-Garza, Braulio A., Shapiro, A.M. James

“…PURPOSE OF REVIEWChronic diabetes-related complications continue to exert a rapidly growing and unsustainable pressure on healthcare systems worldwide. In type…”
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