Search Results - "Marfil, Silvia"

SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity by Trinité, Benjamin, Tarrés-Freixas, Ferran, Rodon, Jordi, Pradenas, Edwards, Urrea, Víctor, Marfil, Silvia, Rodríguez de la Concepción, María Luisa, Ávila-Nieto, Carlos, Aguilar-Gurrieri, Carmen, Barajas, Ana, Ortiz, Raquel, Paredes, Roger, Mateu, Lourdes, Valencia, Alfonso, Guallar, Víctor, Ruiz, Lidia, Grau, Eulàlia, Massanella, Marta, Puig, Jordi, Chamorro, Anna, Izquierdo-Useros, Nuria, Segalés, Joaquim, Clotet, Bonaventura, Carrillo, Jorge, Vergara-Alert, Júlia, Blanco, Julià

“…The protective effect of neutralizing antibodies in SARS-CoV-2 infected individuals is not yet well defined. To address this issue, we have analyzed the…”
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Glucocorticoids’ treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients by Garcia-Cirera, Silvia, Calvet, Joan, Berenguer-Llergo, Antoni, Pradenas, Edwards, Marfil, Silvia, Massanella, Marta, Mateu, Lourdes, Trinité, Benjamin, Llop, Maria, Arévalo, Marta, Galisteo, Carlos, Orellana, Cristóbal, Gómez, Rafael, Gómez-Gerique, María Nieves, Carmona, Inma, Clotet, Bonaventura, Blanco, Julià, Gratacós, Jordi

“…Limited data exists on SARS-CoV-2 sustained-response to vaccine in patients with rheumatic diseases. This study aims to evaluate neutralizing antibodies (nAB)…”
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Physicochemical characterization of the recombinant lectin scytovirin and microbicidal activity of the SD1 domain produced in rice against HIV-1 by Armario-Najera, Victoria, Blanco-Perera, Amaya, Shenoy, Shilpa R., Sun, Yi, Marfil, Silvia, Muñoz-Basagoiti, Jordana, Perez-Zsolt, Daniel, Blanco, Julià, Izquierdo-Useros, Nuria, Capell, Teresa, O’Keefe, Barry R., Christou, Paul

“…Key message Rice-produced SD1 retains its physicochemical properties and provides efficient pre-exposure HIV-1 prophylaxis against infection in vitro…”
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Impact of chemotherapy and/or immunotherapy on neutralizing antibody response to SARS‐CoV‐2 mRNA‐1237 vaccine in patients with solid tumors by Felip, Eudald, Pradenas, Edwards, Romeo, Margarita, Marfil, Silvia, Trinité, Benjamin, Urrea, Víctor, Hernández, Ainhoa, Ballana, Ester, Cucurull, Marc, Mateu, Lourdes, Massanella, Marta, Clotet, Bonaventura, Morán, Teresa, Blanco, Julià

“…Patients with solid tumors have been a risk group since the beginning of the SARS‐CoV‐2 pandemic due to more significant complications, hospitalizations or…”
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An engineered HIV-1 Gag-based VLP displaying high antigen density induces strong antibody-dependent functional immune responses by Tarrés-Freixas, Ferran, Aguilar-Gurrieri, Carmen, Rodríguez de la Concepción, María Luisa, Urrea, Victor, Trinité, Benjamin, Ortiz, Raquel, Pradenas, Edwards, Blanco, Pau, Marfil, Sílvia, Molinos-Albert, Luis Manuel, Barajas, Ana, Pons-Grífols, Anna, Ávila-Nieto, Carlos, Varela, Ismael, Cervera, Laura, Gutiérrez-Granados, Sònia, Segura, María Mercedes, Gòdia, Francesc, Clotet, Bonaventura, Carrillo, Jorge, Blanco, Julià

“…Antigen display on the surface of Virus-Like Particles (VLPs) improves immunogenicity compared to soluble proteins. We hypothesised that immune responses can…”
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First Detection of SARS-CoV-2 Delta (B.1.617.2) Variant of Concern in a Dog with Clinical Signs in Spain by Fernández-Bastit, Leira, Rodon, Jordi, Pradenas, Edwards, Marfil, Silvia, Trinité, Benjamin, Parera, Mariona, Roca, Núria, Pou, Anna, Cantero, Guillermo, Lorca-Oró, Cristina, Carrillo, Jorge, Izquierdo-Useros, Nuria, Clotet, Bonaventura, Noguera-Julián, Marc, Blanco, Julià, Vergara-Alert, Júlia, Segalés, Joaquim

“…Several cases of naturally infected dogs with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported despite the apparently low…”
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The Characteristics of the HIV-1 Env Glycoprotein Are Linked With Viral Pathogenesis by Pérez-Yanes, Silvia, Pernas, María, Marfil, Silvia, Cabrera-Rodríguez, Romina, Ortiz, Raquel, Urrea, Víctor, Rovirosa, Carla, Estévez-Herrera, Judith, Olivares, Isabel, Casado, Concepción, Lopez-Galindez, Cecilio, Blanco, Julià, Valenzuela-Fernández, Agustín

“…The understanding of HIV-1 pathogenesis and clinical progression is incomplete due to the variable contribution of host, immune, and viral factors. The…”
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HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic by Cabrera-Rodríguez, Romina, Hebmann, Veronique, Marfil, Silvia, Pernas, María, Marrero-Hernández, Sara, Cabrera, Cecilia, Urrea, Victor, Casado, Concepción, Olivares, Isabel, Márquez-Arce, Daniel, Pérez-Yanes, Silvia, Estévez-Herrera, Judith, Clotet, Bonaventura, Espert, Lucile, López-Galíndez, Cecilio, Biard-Piechaczyk, Martine, Valenzuela-Fernández, Agustín, Blanco, Julià

“…In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals…”
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Virological and Clinical Determinants of the Magnitude of Humoral Responses to SARS-CoV-2 in Mild-Symptomatic Individuals by Pradenas, Edwards, Ubals, Maria, Urrea, Víctor, Suñer, Clara, Trinité, Benjamin, Riveira-Muñoz, Eva, Marfil, Silvia, Ávila-Nieto, Carlos, Rodríguez de la Concepción, María Luisa, Tarrés-Freixas, Ferran, Laporte, Josep, Ballana, Ester, Carrillo, Jorge, Clotet, Bonaventura, Mitjà, Oriol, Blanco, Julià

“…Evidence on the determinants of the magnitude of humoral responses and neutralizing titers in individuals with mild COVID-19 is scarce. In this cohort study of…”
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Previous SARS-CoV-2 Infection Increases B.1.1.7 Cross-Neutralization by Vaccinated Individuals by Trinité, Benjamin, Pradenas, Edwards, Marfil, Silvia, Rovirosa, Carla, Urrea, Víctor, Tarrés-Freixas, Ferran, Ortiz, Raquel, Rodon, Jordi, Vergara-Alert, Júlia, Segalés, Joaquim, Guallar, Victor, Lepore, Rosalba, Izquierdo-Useros, Nuria, Trujillo, Glòria, Trapé, Jaume, González-Fernández, Carolina, Flor, Antonia, Pérez-Vidal, Rafel, Toledo, Ruth, Chamorro, Anna, Paredes, Roger, Blanco, Ignacio, Grau, Eulàlia, Massanella, Marta, Carrillo, Jorge, Clotet, Bonaventura, Blanco, Julià

“…With the spread of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a need to assess the protection conferred by both…”
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Proteomics of circulating extracellular vesicles reveals diverse clinical presentations of COVID-19 but fails to identify viral peptides by Gualdrón-López, Melisa, Ayllon-Hermida, Alberto, Cortes-Serra, Núria, Resa-Infante, Patricia, Bech-Serra, Joan Josep, Aparici-Herraiz, Iris, Nicolau-Fernandez, Marc, Erkizia, Itziar, Gutierrez-Chamorro, Lucia, Marfil, Silvia, Pradenas, Edwards, Ávila Nieto, Carlos, Cucurull, Bernat, Montaner-Tarbés, Sergio, Muelas, Magdalena, Sotil, Ruth, Ballana, Ester, Urrea, Victor, Fraile, Lorenzo, Montoya, Maria, Vergara, Julia, Segales, Joaquim, Carrillo, Jorge, Izquierdo-Useros, Nuria, Blanco, Julià, Fernandez-Becerra, Carmen, de La Torre, Carolina, Pinazo, Maria-Jesus, Martinez-Picado, Javier, del Portillo, Hernando A.

“…Extracellular vesicles (EVs) released by virus-infected cells have the potential to encapsulate viral peptides, a characteristic that could facilitate vaccine…”
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Demonstration of Antibodies Against SARS-CoV-2, Neutralizing or Binding, in Seroconversion Panels After mRNA-1273, BNT-162b2, and Ad26.COV2.S Vaccine Administration by Belda, Francisco, Mora, Oscar, Lopez-Martinez, Monica, Torres, Nerea, Vivanco, Ana, Marfil, Silvia, Pradenas, Edwards, Massanella, Marta, Blanco, Julià, Christie, Rebecca, Crowley, Michael

“…Vaccines are an important tool in combating the COVID-19 pandemic. Two mRNA vaccines (mRNA-1273 and BNT-162b2) and an adenovirus vector vaccine (Ad26.COV2.S)…”
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Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals by Ainsua-Enrich, Erola, Pedreño-Lopez, Núria, Bracke, Carmen, Ávila-Nieto, Carlos, Rodríguez de la Concepción, María Luisa, Pradenas, Edwards, Trinité, Benjamin, Marfil, Silvia, Miranda, Cristina, González, Sandra, Toledo, Ruth, Font, Marta, Benet, Susana, Escribà, Tuixent, Jimenez-Moyano, Esther, Peña, Ruth, Cedeño, Samandhy, Prado, Julia G., Mothe, Beatriz, Brander, Christian, Izquierdo-Useros, Nuria, Vergara-Alert, Julia, Segalés, Joaquim, Massanella, Marta, Benitez, Rosa María, Romero, Alba, Molina-Morant, Daniel, Blanco, Julià, Clotet, Bonaventura, Mateu, Lourdes, Pedro-Botet, María Luisa, Carrillo, Jorge

“…Mass vaccination campaigns reduced COVID-19 incidence and severity. Here, we evaluated the immune responses developed in SARS-CoV-2-uninfected patients with…”
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Impact of hybrid immunity booster vaccination and Omicron breakthrough infection on SARS-CoV-2 VOCs cross-neutralization by Pradenas, Edwards, Marfil, Silvia, Urrea, Víctor, Trigueros, Macedonia, Pidkova, Tetyana, Pons-Grífols, Anna, Ortiz, Raquel, Rovirosa, Carla, Tarrés-Freixas, Ferran, Aguilar-Gurrieri, Carmen, Toledo, Ruth, Chamorro, Anna, Noguera-Julian, Marc, Mateu, Lourdes, Blanco, Ignacio, Grau, Eulàlia, Massanella, Marta, Carrillo, Jorge, Clotet, Bonaventura, Trinité, Benjamin, Blanco, Julià

“…The elicitation of cross-variant neutralizing antibodies against SARS-CoV-2 represents a major goal for current COVID-19 vaccine strategies. Additionally,…”
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Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates by Prenafeta, Antoni, Bech-Sàbat, Gregori, Moros, Alexandra, Barreiro, Antonio, Fernández, Alex, Cañete, Manuel, Roca, Mercè, González-González, Luis, Garriga, Carme, Confais, Joachim, Toussenot, Marion, Contamin, Hugues, Pizzorno, Andrés, Rosa-Calatrava, Manuel, Pradenas, Edwards, Marfil, Silvia, Blanco, Julià, Rica, Paula Cebollada, Sisteré-Oró, Marta, Meyerhans, Andreas, Lorca, Cristina, Segalés, Joaquim, Prat, Teresa, March, Ricard, Ferrer, Laura

“…SARS-CoV-2 emerged in December 2019 and quickly spread worldwide, continuously striking with an unpredictable evolution. Despite the success in vaccine…”
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Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals by Massanella, Marta, Ouchi, Dan, Marfil, Silvia, Llibre, Josep M, Puertas, Maria C, Buzón, María J, Richman, Douglas D, Orna, Elisa, Stevenson, Mario, Gatell, Josep M, Domingo, Pere, Negredo, Eugènia, Martinez-Picado, Javier, Clotet, Bonaventura, Blanco, Julià

“…HIV-1 infection increases plasma levels of inflammatory markers. Combination antiretroviral therapy (cART) does not restore inflammatory markers to normal…”
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Contribution of the HIV-1 Envelope Glycoprotein to AIDS Pathogenesis and Clinical Progression by Valenzuela-Fernández, Agustín, Cabrera-Rodríguez, Romina, Casado, Concha, Pérez-Yanes, Silvia, Pernas, María, García-Luis, Jonay, Marfil, Silvia, Olivares, Isabel, Estévez-Herrera, Judith, Trujillo-González, Rodrigo, Blanco, Julià, Lopez-Galindez, Cecilio

“…In the absence of antiviral therapy, HIV-1 infection progresses to a wide spectrum of clinical manifestations that are the result of an entangled contribution…”
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Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals by Carrillo, Jorge, Molinos-Albert, Luis Manuel, Rodríguez de la Concepción, Maria Luisa, Marfil, Silvia, García, Elisabet, Derking, Ronald, Sanders, Rogier W, Clotet, Bonaventura, Blanco, Julià

“…Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site…”
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Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression by RUIZ, L, MARTINEZ-PICADO, J, ROMEU, J, PAREDES, R, ZAYAT, M. K, MARFIL, S, NEGREDO, E, SIRERA, G, TURAL, C, CLOTET, B

“…To investigate the virological and immunological impact of a structured treatment interruption (STI) in a cohort of HIV-1 chronically infected patients with a…”
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Genetic evolution of gp41 reveals a highly exclusive relationship between codons 36, 38 and 43 in gp41 under long-term enfuvirtide-containing salvage regimen by CABRERA, Cecilia, MARFIL, Silvia, RUIZ, Lidia, GARCIA, Elisabet, MARTINEZ-PICADO, Javier, BONJOCH, Anna, BOFILL, Margarita, MORENO, Santiago, RIBERA, Esteban, DOMINGO, Pere, CLOTET, Bonaventura

“…To analyse the genetic changes in the gp41 protein in HIV-infected patients with detectable plasma viraemia receiving a long-term salvage enfuvirtide regimen…”
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