Search Results - "Mares, Wout G N"

Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon by Hebels, Dennie G.A.J., Sveje, Kirstine M., de Kok, Marloes C., van Herwijnen, Marcel H.M., Kuhnle, Gunter G.C., Engels, Leopold G.J.B., Vleugels-Simon, Carla B.E.M., Mares, Wout G.N., Pierik, Marieke, Masclee, Ad A.M., Kleinjans, Jos C.S., de Kok, Theo M.C.M.

“…► Fecal water genotoxicity significantly increased after an increase in red meat intake to 300g/day for 7days. ► Oxidative DNA damage is a large contributor to…”
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N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer by Hebels, Dennie G.A.J, Sveje, Kirstine M, de Kok, Marloes C, van Herwijnen, Marcel H.M, Kuhnle, Gunter G.C, Engels, Leopold G.J.B, Vleugels-Simon, Carla B.E.M, Mares, Wout G.N, Pierik, Marieke, Masclee, Ad A.M, Kleinjans, Jos C.S, de Kok, Theo M.C.M

“…Abstract Endogenous formation of N-nitroso compounds (NOCs), which are known animal carcinogens, could contribute to human carcinogenesis but definitive…”
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The effect of administering preprocedural VITamin K on the international normalized ratio in patients anticoagulated with ACEnocoumarol (VITKACE-study): a prospective cohort study by Bijkerk, Stella, Lourens, Harm J., Mares, Wout G.N., van Kampen, Corine A., van der Veen, Maurits J., Adriaansen, Henk J., Ponfoort, Erik D., Festen, Barbara, Westendorp, G. Wouter, Rovers, Jörgen M.P., Groot, Gerie M.C., Bootsma, Hans-Peter R., Amelung, Linde M., Bins, Sander, Velders, Gerjo, Bemelmans, Remy H.H.

“…The effect of the vitamin K antagonist acenocoumarol on coagulation needs to be reversed when patients undergo an invasive procedure with considerable bleeding…”
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Multicentre study and systematic review: Allopurinol exposure during pregnancy by Crouwel, Femke, Simsek, Melek, Boer, Marjon A., Asseldonk, Dirk P., Bhalla, Abha, Weusthuis, Angelique L. M., Gilissen, Lennard P. L., Verburg, Robert J., Mares, Wout G. N., Jharap, Bindia, Kuijvenhoven, Johan P., Oldenburg, Bas, Buiter, Hans J. C., Julsgaard, Mette, Boer, Nanne K.

“…Summary Background Data about the safety of allopurinol in pregnant women are sparsely reported. Aims To investigate the risk of adverse pregnancy outcome and…”
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Therapeutic drug monitoring of methotrexate in patients with Crohn's disease by van de Meeberg, Maartje M, Fidder, Herma H, Oldenburg, Bas, Sundaresan, Janani, Struys, Eduard A, Montazeri, Nahid S M, Mares, Wout G N, Mahmmod, Nofel, van Asseldonk, Dirk P, Lutgens, Maurice W M D, Kuyvenhoven, Johan P, Rietdijk, Svend T, Nissen, Loes H C, Koehestanie, Parweez, de Boer, Nanne K H, de Jonge, Robert, Bouma, Gerd, Bulatović Ćalasan, Maja

“…Therapeutic drug monitoring (TDM) has the potential to improve efficacy and diminish side effects. Measuring methotrexate-polyglutamate (MTX-PG) in…”
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Methotrexate accumulation in target intestinal mucosa and white blood cells differs from non‐target red blood cells of patients with Crohn's disease by Meeberg, Maartje M., Sundaresan, Janani, Lin, Marry, Jansen, Gerrit, Struys, Eduard A., Fidder, Herma H., Oldenburg, Bas, Mares, Wout G. N., Mahmmod, Nofel, Asseldonk, Dirk P., Rietdijk, Svend T., Nissen, Loes H. C., Boer, Nanne K. H., Bouma, Gerd, Ćalasan, Maja Bulatović, Jonge, Robert

“…Background Intracellular methotrexate polyglutamates (MTX‐PGs) concentrations are measurable in red blood cells (RBCs) during MTX treatment. MTX‐PG3…”
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Validation and update of a prediction model for risk of relapse after cessation of anti-TNF treatment in Crohn’s disease by ten Bokkel Huinink, Sebastiaan, de Jong, Djuna C., Nieboer, Daan, Thomassen, Doranne, Steyerberg, Ewout W., Dijkgraaf, Marcel G.W., Bodelier, Alexander G.L., West, Rachel L., Römkens, Tessa E.H., Hoentjen, Frank, Mallant, Rosalie C., van Tuyl, Bas A.C., Mares, Wout G.N., Wolfhagen, Frank H.J., Dijkstra, Gerard, Reijnders, Jurriën G.P., de Boer, Nanne K., Tan, Adriaan C.I.T.L., van Boeckel, Petra G.A., Tack, Greetje J., van Asseldonk, Dirk P., D’Haens, Geert R.A.M., van der Woude, C Janneke, Duijvestein, Marjolijn, de Vries, Annemarie C

“…Background Anti-tumor necrosis factor (TNF) therapy is effective for the treatment of Crohn’s disease. Cessation may be considered in patients with a low risk…”
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Limited predictive value of the gut microbiome and metabolome for response to biological therapy in inflammatory bowel disease by Prins, Femke M, Hidding, Iwan J, Klaassen, Marjolein A Y, Collij, Valerie, Schultheiss, Johannes P D, Uniken Venema, Werna T C, Bangma, Amber, Aardema, Jurne B, Jansen, Bernadien H, Mares, Wout G N, Witteman, Ben J M, Festen, Eleonora A M, Dijkstra, Gerard, Visschedijk, Marijn C, Fidder, Herma H, Vich Vila, Arnau, Oldenburg, Bas, Gacesa, Ranko, Weersma, Rinse K

“…Emerging evidence suggests the gut microbiome's potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In…”
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