Search Results - "Mares, Jaroslav"

Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model by Levová, Katerina, Moserová, Michaela, Kotrbová, Vera, Sulc, Miroslav, Henderson, Colin J, Wolf, C Roland, Phillips, David H, Frei, Eva, Schmeiser, Heinz H, Mares, Jaroslav, Arlt, Volker M, Stiborová, Marie

“…Aristolochic acid (AA) causes aristolochic acid nephropathy, Balkan endemic nephropathy, and their urothelial malignancies. To identify enzymes involved in the…”
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The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases by Stiborová, Marie, Mareîs, Jaroslav, Frei, Eva, Arlt, Volker M., Martínek, Václav, Schmeiser, Heinz H.

“…Ingestion of aristolochic acid (AA) is associated with development of urothelial tumors linked with AA nephropathy and is implicated in the development of…”
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Analysis of genetic events in 17p13 and 9p21 regions supports predominant monoclonal origin of multifocal and recurrent bladder cancer by Trkova, Marie, Babjuk, Marko, Duskova, Jaroslava, Benesova-Minarikova, Lucie, Soukup, Viktor, Mares, Jaroslav, Minarik, Marek, Sedlacek, Zdenek

“…Clonality was tested in 86 tumours from 25 patients with recurrent and multifocal superficial bladder transitional cell carcinomas (TCCs) using the analysis of…”
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Prediction of recurrence in Ta urothelial cell carcinoma by real‐time quantitative PCR analysis: A microarray validation study by Schultz, Iman J., Wester, Kenneth, Straatman, Huub, Kiemeney, Lambertus A., Babjuk, Marko, Mares, Jaroslav, Willems, Johanner L., Swinkels, Dorine W., Witjes, J. Alfred, de Kok, Jacques B., Malmström, Per‐Uno

“…Accurate prediction of tumor recurrence in patients with superficial urothelial cell carcinoma (UCC) might result in a significant reduction of invasive…”
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The SHB Adapter Protein Is Required for Normal Maturation of Mesoderm during in Vitro Differentiation of Embryonic Stem Cells by Kriz, Vitezslav, Ågren, Nina, Lindholm, Cecilia K., Lenell, Samuel, Saldeen, Johan, Mares, Jaroslav, Welsh, Michael

“…Definitive mesoderm arises from a bipotent mesendodermal population, and to study processes controlling its development at this stage, embryonic stem (ES)…”
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Urinary Cell-Free DNA Quantification as Non-Invasive Biomarker in Patients with Bladder Cancer by Brisuda, Antonin, Pazourkova, Eva, Soukup, Viktor, Horinek, Ales, Hrbáček, Jan, Capoun, Otakar, Svobodova, Iveta, Pospisilova, Sarka, Korabecna, Marie, Mares, Jaroslav, Hanuš, Tomáš, Babjuk, Marek

“…Concentration of urinary cell-free DNA (ucfDNA) belongs to potential bladder cancer markers, but the reported results are inconsistent due to the use of…”
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Comparison of MicroRNA Content in Plasma and Urine Indicates the Existence of a Transrenal Passage of Selected MicroRNAs by Pazourkova, Eva, Pospisilova, Sarka, Svobodova, Iveta, Horinek, Ales, Brisuda, Antonin, Soukup, Viktor, Hrbacek, Jan, Capoun, Otakar, Mares, Jaroslav, Hanus, Tomas, Babjuk, Marek, Korabecna, Marie

“…MicroRNAs (miRNAs) in urine are examined as potential biomarkers. We examined the urine samples from 70 individuals (45 males, 25 females, mean age 65 years,…”
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Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth by FUNA, Nina S, KRIZ, Vitezslav, GUANGXIANG ZANG, CALOUNOVA, Gabriela, AKERBLOM, Bjöm, MARES, Jaroslav, LARSSON, Erik, YING SUN, BETSHOLTZ, Christer, WELSH, Michael

“…Shb (Src homology 2 protein B) is an adapter protein downstream of the vascular endothelial growth factor receptor receptor-2 (VEGFR-2). Previous experiments…”
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Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver by Stiborova, Marie, Mares, Jaroslav, Levova, Katerina, Pavlickova, Jana, Barta, Frantisek, Hodek, Petr, Frei, Eva, Schmeiser, Heinz H

“…The herbal drug aristolochic acid (AA) derived from Aristolochia species has been shown to be the cause of aristolochic acid nephropathy (AAN), Balkan endemic…”
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Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero by Kriz, Vitezslav, Mares, Jaroslav, Wentzel, Parri, Funa, Nina S., Calounova, Gabriela, Zhang, Xiao‐Qun, Forsberg‐Nilsson, Karin, Forsberg, Maud, Welsh, Michael

“…SHB is an Src homology 2 domain‐containing adapter protein that has been found to be involved in numerous cellular responses. We have generated an Shb knockout…”
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Gene Expression Analysis for the Prediction of Recurrence in Patients with Primary Ta Urothelial Cell Carcinoma by Schultz, Iman J, Wester, Kenneth, Straatman, Huub, Kiemeney, Lambertus A, Babjuk, Marko, Mares, Jaroslav, Willems, Johannes L, Swinkels, Dorine W, Witjes, J. Alfred, Malmström, Per-Uno, de Kok, Jacques B

“…Abstract Objectives The individual recurrence-free period after primary surgery of patients with Ta urothelial cell carcinoma (UCC) cannot be predicted…”
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Methylation changes in promoter and enhancer regions of the WT1 gene in Wilms’ tumours by Mareš, Jaroslav, Křı́ž, Vı́tězslav, Weinhäusel, Andreas, Vodičková, Šárka, Kodet, Roman, Haas, Oskar A., Sedláček, Zdeněk, Goetz, Petr

“…Although the WT1 gene has been implicated in the aetiology of Wilms’ tumour, mutations in WT1 are found only in minority of the tumours. DNA methylation of…”
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The SHB adapter protein is required for efficient multilineage differentiation of mouse embryonic stem cells by Kriz, Vitezslav, Annerén, Cecilia, Lai, Cheng, Karlsson, Jacob, Mares, Jaroslav, Welsh, Michael

“…The SH2 domain-containing adapter protein SHB transmits signals from receptor tyrosine kinases regulating diverse processes such as apoptosis and…”
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Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlates with clinicopathological parameters by Klamt, Barbara, Schulze, Michael, Thäte, Claudia, Mares, Jaroslav, Goetz, Peter, Kodet, Roman, Scheurlen, Wolfram, Weirich, Angela, Graf, Norbert, Gessler, Manfred

“…An extended analysis for loss of heterozygosity (LOH) on eight chromosomes was conducted in a series of 82 Wilms tumors. Observed rates of allele loss were:…”
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Shb is a ubiquitously expressed Src homology 2 protein by Welsh, M, Mares, J, Karlsson, T, Lavergne, C, Bréant, B, Claesson-Welsh, L

“…To identify serum-inducible genes in the insulin-producing cell line beta TC-1, a library subtraction screening procedure was performed on serum-deprived (G0)…”
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Control of SHB gene expression by protein phosphorylation by Lavergne, Corinne, Mares, Jaroslav, Karlsson, Torbjörn, Bréant, Bernadette, Welsh, Michael

“…To increase our understanding of the role of the Src homology 2 (SH2) domain-containing protein Shb in the mitogenic signal transduction, Shb mRNA contents…”
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NEW SPECIES OF MANTICHORA FABR ( Coleoptera , Cicindelidae, Mantichorini) Mantichora imperator n. sp by Jaroslav Mares

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A chimera between platelet-derived growth factor beta-receptor and fibroblast growth factor receptor-1 stimulates pancreatic beta-cell DNA synthesis in the presence of PDGF-BB by Mares, J, Claesson-Welsh, L, Welsh, M

“…This study was undertaken to characterize the expression of a chimeric growth factor receptor composed of the extracellular and transmembrane domains of the…”
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Genetic factors of importance for beta-cell proliferation by Welsh, M, Mares, J, Oberg, C, Karlsson, T

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Purification and properties of phosphoenolpyruvate carboxylase from green leaves of maize by Mares, J, Barthova, J, Leblova, S

“…Phosphoenolpyruvate carboxylate was isolated from green leaves of maize ( Zea mays L.) by a procedure including fractionation with ammonium sulphate,…”
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