Search Results - "Marenda, Daniel R"

The CHD Protein Kismet Restricts the Synaptic Localization of Cell Adhesion Molecules at the Drosophila Neuromuscular Junction by Smith, Ireland R, Hendricks, Emily L, Latcheva, Nina K, Marenda, Daniel R, Liebl, Faith L W

“…The appropriate expression and localization of cell surface cell adhesion molecules must be tightly regulated for optimal synaptic growth and function. How…”
Get full text

Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects by Chakraborty, Ranjita, Vepuri, Vidya, Mhatre, Siddhita D, Paddock, Brie E, Miller, Sean, Michelson, Sarah J, Delvadia, Radha, Desai, Arkit, Vinokur, Marianna, Melicharek, David J, Utreja, Suruchi, Khandelwal, Preeti, Ansaloni, Sara, Goldstein, Lee E, Moir, Robert D, Lee, Jeremy C, Tabb, Loni P, Saunders, Aleister J, Marenda, Daniel R

“…Transgenic models of Alzheimer's disease (AD) have made significant contributions to our understanding of AD pathogenesis, and are useful tools in the…”
Get full text

Erythritol, a non-nutritive sugar alcohol sweetener and the main component of truvia®, is a palatable ingested insecticide by Baudier, Kaitlin M, Kaschock-Marenda, Simon D, Patel, Nirali, Diangelus, Katherine L, O'Donnell, Sean, Marenda, Daniel R

“…Insecticides have a variety of commercial applications including urban pest control, agricultural use to increase crop yields, and prevention of proliferation…”
Get full text

Association of the Protein-Quality-Control Protein Ubiquilin-1 With Alzheimer's Disease Both in vitro and in vivo by Zhang, Can, Inamdar, Shivangi M, Swaminathan, Swathi, Marenda, Daniel R, Saunders, Aleister J

“…Alzheimer's disease (AD) belongs to a class of diseases characterized by progressive accumulation and aggregation of pathogenic proteins, particularly Aβ…”
Get full text

Mannitol ingestion causes concentration-dependent, sex-biased mortality in adults of the fruit fly (Drosophila melanogaster) by Fiocca, Katherine, Barrett, Meghan, Waddell, Edward A, Viveiros, Jennifer, McNair, Cheyenne, O'Donnell, Sean, Marenda, Daniel R

“…Mannitol, a sugar alcohol used in commercial food products, has been previously shown to induce sex-biased mortality in female Drosophila melanogaster when…”
Get full text

Type I bHLH Proteins Daughterless and Tcf4 Restrict Neurite Branching and Synapse Formation by Repressing Neurexin in Postmitotic Neurons by D’Rozario, Mitchell, Zhang, Ting, Waddell, Edward A., Zhang, Yonggang, Sahin, Cem, Sharoni, Michal, Hu, Tina, Nayal, Mohammad, Kutty, Kaveesh, Liebl, Faith, Hu, Wenhui, Marenda, Daniel R.

“…Proneural proteins of the class I/II basic-helix-loop-helix (bHLH) family are highly conserved transcription factors. Class I bHLH proteins are expressed in a…”
Get full text

The CHD Protein, Kismet, is Important for the Recycling of Synaptic Vesicles during Endocytosis by Latcheva, Nina K., Delaney, Taylor L., Viveiros, Jennifer M., Smith, Rachel A., Bernard, Kelsey M., Harsin, Benjamin, Marenda, Daniel R., Liebl, Faith L. W.

“…Chromatin remodeling proteins of the chromodomain DNA-binding protein family, CHD7 and CHD8, mediate early neurodevelopmental events including neural migration…”
Get full text

Synaptic abnormalities in a Drosophila model of Alzheimer's disease by Mhatre, Siddhita D, Satyasi, Vivek, Killen, Mark, Paddock, Brie E, Moir, Robert D, Saunders, Aleister J, Marenda, Daniel R

“…Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by memory loss and decreased synaptic function. Advances in transgenic…”
Get full text

The Drosophila Chromodomain Protein Kismet Activates Steroid Hormone Receptor Transcription to Govern Axon Pruning and Memory In Vivo by Latcheva, Nina K, Viveiros, Jennifer M, Marenda, Daniel R

“…Axon pruning is critical for sculpting precise neural circuits. Although axon pruning has been described in the literature for decades, relatively little is…”
Get full text

Kismet positively regulates glutamate receptor localization and synaptic transmission at the Drosophila neuromuscular junction by Ghosh, Rupa, Vegesna, Srikar, Safi, Ramia, Bao, Hong, Zhang, Bing, Marenda, Daniel R, Liebl, Faith L W

“…The Drosophila neuromuscular junction (NMJ) is a glutamatergic synapse that is structurally and functionally similar to mammalian glutamatergic synapses. These…”
Get full text

Larval mannitol diets increase mortality, prolong development and decrease adult body sizes in fruit flies ( Drosophila melanogaster ) by Barrett, Meghan, Fiocca, Katherine, Waddell, Edward A, McNair, Cheyenne, O'Donnell, Sean, Marenda, Daniel R

“…The ability of polyols to disrupt holometabolous insect development has not been studied and identifying compounds in food that affect insect development can…”
Get full text

Histone lysine demethylases function as co-repressors of SWI/SNF remodeling activities during Drosophila wing development by Curtis, Brenda J., Zraly, Claudia B., Marenda, Daniel R., Dingwall, Andrew K.

“…The conserved SWI/SNF chromatin remodeling complex uses the energy from ATP hydrolysis to alter local chromatin environments through disrupting DNA-histone…”
Get full text

The epigenetics of CHARGE syndrome by Latcheva, Nina K, Rupa Ghosh, Daniel R. Marenda

“…In biology, we continue to appreciate the fact that the DNA sequence alone falls short when attempting to explain the intricate inheritance patterns for…”
Get full text

Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules by Leo, Lanfranco, Yu, Wenqian, D’Rozario, Mitchell, Waddell, Edward A., Marenda, Daniel R., Baird, Michelle A., Davidson, Michael W., Zhou, Bin, Wu, Bingro, Baker, Lisa, Sharp, David J., Baas, Peter W.

“…Individual microtubules (MTs) in the axon consist of a stable domain that is highly acetylated and a labile domain that is not. Traditional MT-severing…”
Get full text

Erythritol Ingestion Causes Concentration-Dependent Mortality in Eastern Subterranean Termites (Blattodea: Rhinotermitidae) by Caponera, Virginia, Barrett, Meghan, Marenda, Daniel R, O'Donnell, Sean

“…Damage from termite infestations is economically significant and control can be costly when requiring the widespread use of conventional insecticides…”
Get full text

Potential for Use of Erythritol as a Socially Transferrable Ingested Insecticide for Ants (Hymenoptera: Formicidae) by Barrett, Meghan, Caponera, Virginia, McNair, Cheyenne, O'Donnell, Sean, Marenda, Daniel R

“…Ants are significant structural and agricultural pests, generating a need for human-safe and effective insecticides for ant control. Erythritol, a sugar…”
Get full text

MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing by Marenda, Daniel R, Vrailas, Alysia D, Rodrigues, Aloma B, Cook, Summer, Powers, Maureen A, Lorenzen, James A, Perkins, Lizabeth A, Moses, Kevin

“…Mitogen-activated protein kinases (MAPKs) phosphorylate target proteins in both the cytoplasm and nucleus, and a strong correlation exists between the…”
Get full text

Non-Nutritive Polyol Sweeteners Differ in Insecticidal Activity When Ingested by Adult Drosophila melanogaster (Diptera: Drosophilidae) by O'Donnell, Sean, Baudier, Kaitlin, Marenda, Daniel R

“…Previous work showed the non-nutritive polyol sweetener Erythritol was toxic when ingested by Drosophila melanogaster (Meigen, 1930). This study assessed…”
Get full text

Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics by Solowska, Joanna M, D'Rozario, Mitchell, Jean, Daphney C, Davidson, Michael W, Marenda, Daniel R, Baas, Peter W

“…Mutations to the SPG4 gene encoding the microtubule-severing protein spastin are the most common cause of hereditary spastic paraplegia. Haploinsufficiency,…”
Get full text

SNR1 is an essential subunit in a subset of drosophila brm complexes, targeting specific functions during development by Zraly, Claudia B, Marenda, Daniel R, Nanchal, Runjhun, Cavalli, Giacomo, Muchardt, Christian, Dingwall, Andrew K

“…The snr1 gene of Drosophila melanogaster encodes a conserved component of the multiprotein Brahma (Brm) complex, a counterpart to the SWI/SNF complexes that…”
Get full text