Search Results - "Maree, C"

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis by Samson, Andre L., Zhang, Ying, Geoghegan, Niall D., Gavin, Xavier J., Davies, Katherine A., Mlodzianoski, Michael J., Whitehead, Lachlan W., Frank, Daniel, Garnish, Sarah E., Fitzgibbon, Cheree, Hempel, Anne, Young, Samuel N., Jacobsen, Annette V., Cawthorne, Wayne, Petrie, Emma J., Faux, Maree C., Shield-Artin, Kristy, Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Rogers, Kelly L., Lessene, Guillaume, Hawkins, Edwin D., Murphy, James M.

“…Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory necroptotic cell death program. RIPK3-mediated phosphorylation is…”
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APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells by Faux, Maree C, King, Lauren E, Kane, Serena R, Love, Christopher, Sieber, Oliver M, Burgess, Antony W

“…The adenomatous polyposis coli (APC) tumor suppressor protein is associated with the regulation of Wnt signaling; however, APC also controls other cellular…”
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Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen by King, Lauren E, Zhang, Hui-Hua, Gould, Cathryn M, Thomas, Daniel W, Whitehead, Lachlan W, Simpson, Kaylene J, Burgess, Antony W, Faux, Maree C

“…Truncating mutations in the tumour suppressor gene APC occur frequently in colorectal cancers and result in the deregulation of Wnt signalling as well as…”
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Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes by Leung, Ryan F, George, Ankita M, Roussel, Enola M, Faux, Maree C, Wigle, Jeffrey T, Eisenstat, David D

“…Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and…”
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The Landscape of Pediatric High-Grade Gliomas: The Virtues and Pitfalls of Pre-Clinical Models by Furst, Liam M, Roussel, Enola M, Leung, Ryan F, George, Ankita M, Best, Sarah A, Whittle, James R, Firestein, Ron, Faux, Maree C, Eisenstat, David D

“…Pediatric high-grade gliomas (pHGG) are malignant and usually fatal central nervous system (CNS) WHO Grade 4 tumors. The majority of pHGG consist of diffuse…”
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Wnt signaling and colon tumorigenesis — A view from the periphery by Burgess, Antony W., Faux, Maree C., Layton, Meredith J., Ramsay, Robert G.

“…In this brief overview we discuss the association between Wnt signaling and colon cell biology and tumorigenesis. Our current understanding of the role of Apc…”
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Use of the IL‐6R antagonist tocilizumab in hospitalized COVID‐19 patients by Patel, K., Gooley, T. A., Bailey, N., Bailey, M., Hegerova, L., Batchelder, A., Holdread, H., Dunleavy, V., Downey, T., Frisvold, J., Megrath, S., Pagarigan, K., Szeto, J., Rueda, J., Islam, A., Maree, C., Nyatsatsang, S., Bork, S. E., Lipke, A., O’Mahony, D. S., Wagner, T., Pulido, J., Mignone, J., Youssef, S., Hartman, M., Goldman, J. D., Pagel, J. M.

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Smartphone Microscopy of Parasite Eggs Accumulated into a Single Field of View by Sowerby, Stephen J, Crump, John A, Johnstone, Maree C, Krause, Kurt L, Hill, Philip C

“…A Nokia Lumia 1020 cellular phone (Microsoft Corp., Auckland, New Zealand) was configured to image the ova of Ascaris lumbricoides converged into a single…”
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Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo by Buchert, Michael, Athineos, Dimitris, Abud, Helen E, Burke, Zoe D, Faux, Maree C, Samuel, Michael S, Jarnicki, Andrew G, Winbanks, Catherine E, Newton, Ian P, Meniel, Valerie S, Suzuki, Hiromu, Stacker, Steven A, Näthke, Inke S, Tosh, David, Huelsken, Joerg, Clarke, Alan R, Heath, Joan K, Sansom, Owen J, Ernst, Matthias

“…Contributions of null and hypomorphic alleles of Apc in mice produce both developmental and pathophysiological phenotypes. To ascribe the resulting…”
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Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions by Faux, Maree C, Coates, Janine L, Kershaw, Nadia J, Layton, Meredith J, Burgess, Antony W

“…The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration…”
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Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress by Byrne, Frances L., Olzomer, Ellen M., Marriott, Gabriella R., Quek, Lake-Ee, Katen, Alice, Su, Jacky, Nelson, Marin E., Hart-Smith, Gene, Larance, Mark, Sebesfi, Veronica F., Cuff, Jeff, Martyn, Gabriella E., Childress, Elizabeth, Alexopoulos, Stephanie J., Poon, Ivan K., Faux, Maree C., Burgess, Antony W., Reid, Glen, McCarroll, Joshua A., Santos, Webster L., Quinlan, Kate GR, Turner, Nigel, Fazakerley, Daniel J., Kumar, Naresh, Hoehn, Kyle L.

“…A hallmark of cancer cells is their ability to reprogram nutrient metabolism. Thus, disruption to this phenotype is a potential avenue for anti-cancer therapy…”
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PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis by SAKTHIANANDESWAREN, Anuratha, CHRISTIE, Michael, RAMSAY, Robert G, PHESSE, Toby J, ERNST, Matthias, JEFFERY, Rosemary E, POULSOM, Richard, LEEDHAM, Simon J, SEGDITSAS, Stefania, TOMLINSON, Ian P. M, BERNHARD, Oliver K, SIMPSON, Richard J, D'ANDRETI, Carla, WALKER, Francesca, FAUX, Maree C, CHURCH, Nicole, CATIMEL, Bruno, FLANAGAN, Dustin J, VINCAN, Elizabeth, SIEBER, Oliver M, TSUI, Cary, JORISSEN, Robert N, SHAN LI, FLEMING, Nicholas I, GIBBS, Peter, LIPTON, Lara, MALATERRE, Jordane

“…Studies employing mouse models have identified crypt base and position +4 cells as strong candidates for intestinal epithelial stem cells. Equivalent cell…”
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Competencies for structured professional development of neonatal nurses in South Africa by Maree, C, Scheepers, M. Detken, Janse van Rensburg, E.S

“…Background. The unpredictability of any illness at birth, and recovery from such an illness after birth, create challenges for nurses involved in neonatal…”
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The tumor suppressor Apc controls planar cell polarities central to gut homeostasis by Bellis, Julien, Duluc, Isabelle, Romagnolo, Béatrice, Perret, Christine, Faux, Maree C, Dujardin, Denis, Formstone, Caroline, Lightowler, Sally, Ramsay, Robert G, Freund, Jean-Noël, De Mey, Jan R

“…The stem cells (SCs) at the bottom of intestinal crypts tightly contact niche-supporting cells and fuel the extraordinary tissue renewal of intestinal…”
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Combined Treatment with a WNT Inhibitor and the NSAID Sulindac Reduces Colon Adenoma Burden in Mice with Truncated APC by Faux, Maree C, Weinstock, Janet, Gogos, Sophia, Prato, Emma, Azimpour, Alexander I, O'Keefe, Ryan, Cathcart-King, Yasmin, Garnham, Alexandra L, Ernst, Matthias, Preaudet, Adele, Christie, Michael, Putoczki, Tracy L, Buchert, Michael, Burgess, Antony W

“…Adenomatous polyposis coli (APC) truncations occur in many colorectal cancers and are often associated with immune infiltration. The aim of this study was to…”
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Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4 by Lim, Justin W. E., Mathias, Rommel A., Kapp, Eugene A., Layton, Meredith J., Faux, Maree C., Burgess, Antony W., Ji, Hong, Simpson, Richard J.

“…Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene are common in both inherited and sporadic forms of colorectal cancer (CRC), and are…”
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Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion by Faux, Maree C, Ross, Janine L, Meeker, Clare, Johns, Terry, Ji, Hong, Simpson, Richard J, Layton, Meredith J, Burgess, Antony W

“…The APC tumour suppressor gene is mutated in most colon cancers. A major role of APC is the downregulation of the beta-catenin/T-cell factor (Tcf)/lymphoid…”
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Designing interprofessional modules for undergraduate healthcare learners by Engelbrecht, L., Bresser, P., Maree, C., Viviers, C., Mostert, K., Yazbek, M., Kekana, M.

“…Background. Interprofessional education aims to prepare learners to collaborate across specialties to provide high-quality healthcare. Internationally and…”
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Coordination of Three Signaling Enzymes by AKAP79, a Mammalian Scaffold Protein by Klauck, Theresa M., Faux, Maree C., Labudda, Kirstin, Langeberg, Lorene K., Jaken, Susan, Scott, John D.

“…Multivalent binding proteins, such as the yeast scaffold protein Sterile-5, coordinate the location of kinases by serving as platforms for the assembly of…”
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Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells by King, Lauren E., Love, Christopher G., Sieber, Oliver M., Faux, Maree C., Burgess, Antony W.

“…The adenomatous polyposis coli (APC) tumour suppressor gene is mutated in about 80% of colorectal cancers (CRC) Brannon et al. (2014) [1]. APC is a large…”
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