Search Results - "Mardini, Hanan"

Magnetic resonance quantification of water and metabolites in the brain of cirrhotics following induced hyperammonaemia by Mardini, Hanan, Smith, Fiona E, Record, Christopher O, Blamire, Andrew M

“…Background & Aims Hepatic encephalopathy (HE) is now thought to be caused by cerebral oedema although the precise pathogenesis is uncertain. We hypothesised…”
Get full text

Amino acid challenge in patients with cirrhosis and control subjects : Ammonia, plasma amino acid and EEG changes by AL MARDINI, Hanan, DOUGLASS, Andrew, RECORD, Christopher

“…The pathogenesis of hepatic encephalopathy (HE) is controversial. We have therefore studied the effect of induced hyperammonaemia in man. 108 g of an amino…”
Get full text

Pathogenesis of hepatic encephalopathy: lessons from nitrogen challenges in man by Mardini, Hanan, Record, Christopher

“…Induction of hyperammonaemia with nitrogen challenge in man can be used to study the pathogenesis and treatment of hepatic encephalopathy complicating…”
Get full text

SEQUENTIAL QUANTITATIVE ANALYSIS OF OVAL CELL PROLIFERATION IN THIOACETAMIDE TREATED RATS by Zaitoun, Abdul M, Record, Christopher O, Al-Mardini, Hanan

“…Oval cells are the progeny of facultative stem cells found in the periportal areas in response to liver injury in experimental animals and humans. The aims of…”
Get full text

Quantitative studies of testicular atrophy following portacaval shunt in rats by Zaitoun, Abd M., Apelqvist, Gustav, Wikell, Cecilia, Al‐mardini, Hanan, Bengtsson, Finn, Record, Christopher O.

“…To evaluate the differential effects of portacaval shunting (PCS) on the morphological changes that occur in humans with portal‐systemic encephalopathy, male…”
Get full text

Computerized Psychometric Testing in Minimal Encephalopathy and Modulation by Nitrogen Challenge and Liver Transplant by Mardini, Hanan, Saxby, Brian K, Record, Christopher O

“…Background & Aims A lack of standardized tests was cited by hepatologists for not testing for minimal hepatic encephalopathy. We therefore compared paper and…”
Get full text

Brain indoles in human hepatic encephalopathy by al Mardini, H, Harrison, E J, Ince, P G, Bartlett, K, Record, C O

“…The neurotransmitter serotonin has a profound effect on the control of sleep; thus excess serotonin activity in the brain could be responsible for impaired…”
Get more information

Tu1025 Validation of Transient Elastography in Predicting Advanced Fibrosis and Cirrhosis-a Local Perspective by Taha, Hatim, Bassendine, Margaret F, Hudson, Mark, Record, Christopher, Mardini, Hanan, Baxter, Kerry, Miller, Carolyn, McPherson, Stuart

Get full text

Reply to: “Ammonia and cerebral water. Importance of structural analysis of the brain in hepatic encephalopathy” by Smith, Fiona Elizabeth, Mardini, Hanan, Record, Christopher O, Blamire, Andrew M

Get full text

Synaptosomal glutamate transport in thioacetamide-induced hepatic encephalopathy in the rat by Oppong, K N, Bartlett, K, Record, C O, al Mardini, H

“…Dysfunction of excitatory glutamatergic neurotransmission has been implicated in the cause of hepatic encephalopathy. Brain microdialysis studies in various…”
Get more information

A method of enhancing verocytotoxin production by Escherichia coli by al-Jumaili, I, Burke, D A, Scotland, S M, al-Mardini, H, Record, C O

“…The number of verocytotoxin producing Escherichia coli (VTEC) present in the faeces during an infection may be very low, making their detection difficult. We…”
Get more information

Oral tryptophan challenge studies in cirrhotic patients: No evidence of neuropsychiatric changes by DOUGLASS, Andrew, HANAN AL MARDINI, RECORD, Christopher O

“…Hepatic encephalopathy is a frequent complication of cirrhosis. Abnormalities of 5-hydroxytryptamine (5-HT) and its metabolites are recognized and may…”
Get full text

Amino acid challenge in patients with cirrhosis: a model for the assessment of treatments for hepatic encephalopathy by Douglass, Andrew, Al Mardini, Hanan, Record, Christopher

“…Background/Aims: To mimic episodic hepatic encephalopathy after gastrointestinal bleeding under controlled conditions, cirrhotic patients were challenged with…”
Get full text

Quantitative Studies of Liver Atrophy After Portacaval Shunt in the Rat by Zaitoun, Abed Almuti, Apelqvist, Gustav, Al-Mardini, Hanan, Gray, Trevor, Bengtsson, Finn, Record, Christopher Oswold

“…It is well known that portacaval shunting ultimately leads to a decrease in liver volume and hepatic function, but the mechanism is uncertain. The aim of the…”
Get full text

Oral glutamine challenge in cirrhotics pre‐ and post‐liver transplantation: A psychometric and analyzed EEG study by Oppong, K N, Al‐Mardini, H, Thick, M, Record, C O

“…Latent or sub‐clinical hepatic encephalopathy is a recognized complication of cirrhosis and is thought to represent one end of the spectrum of neuropsychiatric…”
Get full text

An HPLC assay for sn-1,2-diacylglycerol by Eaton, Simon, Shmueli, Ehoud, Al-Mardini, Hanan, Bartlett, Kim, Record, Christopher O.

“…A method for the analysis of 1,2-diacylglycerols in biological samples is presented. After tissue extraction and derivatisation with 3,5-dinitrobenzoyl…”
Get full text

Hepatitis C virus genotypes in a cohort of Middle Eastern patients by Watson, J P, Al-Mardini, H, Awadh, S, Ukabam, S, Record, C O

“…The epidemiology of hepatitis C virus infection has been well characterized in Western Europe, North America and Japan. Less is known about it in other regions…”
Get full text

An improved gas chromatographic method for the detection and quantitation of mercaptans in blood by Mardini, H A, Bartlett, K, Record, C O

Get more information