Search Results - "Mardaryev, Andrei"

Method to Study Skin Cancer: Two-Stage Chemically Induced Carcinogenesis in Mouse Skin by Mardaryev, Andrei N

“…Two-stage chemical carcinogenesis method is widely used to elucidate genetic and molecular changes that lead to skin cancer development, as well as to test…”
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MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway by Ahmed, Mohammed I, Alam, Majid, Emelianov, Vladimir U, Poterlowicz, Krzysztof, Patel, Ankit, Sharov, Andrey A, Mardaryev, Andrei N, Botchkareva, Natalia V

“…Skin development is governed by complex programs of gene activation and silencing, including microRNA-dependent modulation of gene expression. Here, we show…”
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A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle by Buscone, Serena, Mardaryev, Andrei N., Raafs, Bianca, Bikker, Jan W., Sticht, Carsten, Gretz, Norbert, Farjo, Nilofer, Uzunbajakava, Natallia E., Botchkareva, Natalia V.

“…Background and Objective Though devices for hair growth based on low levels of light have shown encouraging results, further improvements of their efficacy is…”
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Exploring a Role for Regulatory miRNAs In Wound Healing during Ageing:Involvement of miR-200c in wound repair by Aunin, Eerik, Broadley, David, Ahmed, Mohammed I., Mardaryev, Andrei N., Botchkareva, Natalia V.

“…Multiple factors and conditions can lead to impaired wound healing. Chronic non-healing wounds are a common problem among the elderly. To identify microRNAs…”
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5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells by Poterlowicz, Krzysztof, Yarker, Joanne L, Malashchuk, Igor, Lajoie, Brian R, Mardaryev, Andrei N, Gdula, Michal R, Sharov, Andrey A, Kohwi-Shigematsu, Terumi, Botchkarev, Vladimir A, Fessing, Michael Y

“…Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin…”
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Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle by Mardaryev, Andrei N, Ahmed, Mohammed I, Vlahov, Nikola V, Fessing, Michael Y, Gill, Jason H, Sharov, Andrey A, Botchkareva, Natalia V

“…The hair follicle is a cyclic biological system that progresses through stages of growth, regression, and quiescence, which involves dynamic changes in a…”
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3D-FISH Analysis of the Spatial Genome Organization in Skin Cells in Situ by Mardaryev, Andrei N, Fessing, Michael Y

“…Spatial genome organization in the cell nucleus plays a crucial role in the control of genome functions. Our knowledge about spatial genome organization is…”
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Cryptochrome 1 is modulated by blue light in human keratinocytes and exerts positive impact on human hair growth by Buscone, Serena, Mardaryev, Andrei N., Westgate, Gillian E., Uzunbajakava, Natallia E., Botchkareva, Natalia V.

“…Photoactivation of cryptochrome‐family proteins by blue light is a well‐established reaction regulating physiology of plants, fungi, bacteria, insects and…”
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p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis by Fessing, Michael Y, Mardaryev, Andrei N, Gdula, Michal R, Sharov, Andrey A, Sharova, Tatyana Y, Rapisarda, Valentina, Gordon, Konstantin B, Smorodchenko, Anna D, Poterlowicz, Krzysztof, Ferone, Giustina, Kohwi, Yoshinori, Missero, Caterina, Kohwi-Shigematsu, Terumi, Botchkarev, Vladimir A

“…During development, multipotent progenitor cells establish tissue-specific programs of gene expression. In this paper, we show that p63 transcription factor, a…”
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Epigenetic Regulation of Gene Expression in Keratinocytes by Botchkarev, Vladimir A., Gdula, Michal R., Mardaryev, Andrei N., Sharov, Andrei A., Fessing, Michael Y.

“…The nucleus is a complex and highly compartmentalized organelle, which undergoes major organization changes during cell differentiation, allowing cells to…”
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Repressing the Keratinocyte Genome: How the Polycomb Complex Subunits Operate in Concert to Control Skin and Hair Follicle Development by Botchkarev, Vladimir A., Mardaryev, Andrei N.

“…The Polycomb group proteins are transcriptional repressors that are critically important in the control of stem cell activity and maintenance of the identity…”
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Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes by Fatima, Iqra, Chen, Guodong, Botchkareva, Natalia V., Sharov, Andrey A., Thornton, Daniel, Wilkinson, Holly N., Hardman, Matthew J., Grutzkau, Andreas, Pedro de Magalhaes, Joao, Seluanov, Andrei, Smith, Ewan St.J., Gorbunova, Vera, Mardaryev, Andrei N., Faulkes, Chris G., Botchkarev, Vladimir A.

“…Naked mole-rats (NMRs) (Heterocephalus glaber) are long-lived mammals that possess a natural resistance to cancer and other age-related pathologies,…”
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Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging by Ahmed, Mohammed I., Pickup, Maximilian E., Rimmer, Alexander G., Alam, Majid, Mardaryev, Andrei N., Poterlowicz, Krzysztof, Botchkareva, Natalia V., Botchkarev, Vladimir A.

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Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium by Mardaryev, Andrei N, Liu, Bo, Rapisarda, Valentina, Poterlowicz, Krzysztof, Malashchuk, Igor, Rudolf, Jana, Sharov, Andrey A, Jahoda, Colin A, Fessing, Michael Y, Benitah, Salvador A, Xu, Guo-Liang, Botchkarev, Vladimir A

“…During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into…”
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Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury by Mardaryev, Andrei N, Meier, Natalia, Poterlowicz, Krzysztof, Sharov, Andrey A, Sharova, Tatyana Y, Ahmed, Mohammed I, Rapisarda, Valentina, Lewis, Christopher, Fessing, Michael Y, Ruenger, Thomas M, Bhawan, Jag, Werner, Sabine, Paus, Ralf, Botchkarev, Vladimir A

“…The Lhx2 transcription factor plays essential roles in morphogenesis and patterning of ectodermal derivatives as well as in controlling stem cell activity…”
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Bone Morphogenetic Protein Signaling Suppresses Wound-Induced Skin Repair by Inhibiting Keratinocyte Proliferation and Migration by Lewis, Christopher J., Mardaryev, Andrei N., Poterlowicz, Krzysztof, Sharova, Tatyana Y., Aziz, Ahmar, Sharpe, David T., Botchkareva, Natalia V., Sharov, Andrey A.

“…Bone morphogenetic protein (BMP) signaling plays a key role in the control of skin development and postnatal remodeling by regulating keratinocyte…”
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p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells by Mardaryev, Andrei N, Gdula, Michal R, Yarker, Joanne L, Emelianov, Vladimir U, Emelianov, Vladimir N, Poterlowicz, Krzysztof, Sharov, Andrey A, Sharova, Tatyana Y, Scarpa, Julie A, Joffe, Boris, Solovei, Irina, Chambon, Pierre, Botchkarev, Vladimir A, Fessing, Michael Y

“…Chromatin structural states and their remodelling, including higher-order chromatin folding and three-dimensional (3D) genome organisation, play an important…”
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MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes by Ahmed, Mohammed I, Mardaryev, Andrei N, Lewis, Christopher J, Sharov, Andrey A, Botchkareva, Natalia V

“…Bone morphogenetic proteins (BMPs) play essential roles in the control of skin development, postnatal tissue remodelling and tumorigenesis. To explore whether…”
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Remodeling of Three-Dimensional Organization of the Nucleus during Terminal Keratinocyte Differentiation in the Epidermis by Gdula, Michal R., Poterlowicz, Krzysztof, Mardaryev, Andrei N., Sharov, Andrey A., Peng, Yonghong, Fessing, Michael Y., Botchkarev, Vladimir A.

“…The nucleus of epidermal keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly changed during terminal…”
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Cbx4 regulates the proliferation of thymic epithelial cells and thymus function by Liu, Bo, Liu, Yuan-Feng, Du, Ya-Rui, Mardaryev, Andrei N, Yang, Wei, Chen, Hui, Xu, Zhi-Mei, Xu, Chen-Qi, Zhang, Xiao-Ren, Botchkarev, Vladimir A, Zhang, Yu, Xu, Guo-Liang

“…Thymic epithelial cells (TECs) are the main component of the thymic stroma, which supports T-cell proliferation and repertoire selection. Here, we demonstrate…”
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