Search Results - "Marczak, Łukasz"
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Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs−/− mice and thrombosis-prone CBS−/− humans
Published in Scientific reports (01-07-2020)“…Cystathionine β-synthase (CBS)-deficient patients are prone to vascular thrombosis. In contrast, Cbs −/− mice show no abnormalities in blood coagulation. To…”
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2
An Optimized Method of Metabolite Extraction from Formalin-Fixed Paraffin-Embedded Tissue for GC/MS Analysis
Published in PloS one (08-09-2015)“…Formalin-fixed paraffin-embedded (FFPE) tissue specimens constitute a highly valuable source of clinical material for retrospective molecular studies. However,…”
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Detection of metabolites discriminating subtypes of thyroid cancer: Molecular profiling of FFPE samples using the GC/MS approach
Published in Molecular and cellular endocrinology (05-12-2015)“…One of the critical issues in thyroid cancer diagnostic is differentiation between follicular adenoma, follicular carcinoma and the follicular variant of…”
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The Metabolite Content of the Post-Culture Medium of the Tree Fern Cyathea delgadii Sternb. Cell Suspension Cultured in the Presence of 2,4-D and BAP
Published in International journal of molecular sciences (04-10-2022)“…The aim of this study was to demonstrate the metabolic profile of post-culture medium as an expression of cell suspension metabolic activity of the tree fern…”
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Analysis of Drought-Induced Proteomic and Metabolomic Changes in Barley (Hordeum vulgare L.) Leaves and Roots Unravels Some Aspects of Biochemical Mechanisms Involved in Drought Tolerance
Published in Frontiers in plant science (26-07-2016)“…In this study, proteomic and metabolomic changes in leaves and roots of two barley (Hordeum vulgare L.) genotypes, with contrasting drought tolerance,…”
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Impaired interactions of ataxin-3 with protein complexes reveals their specific structure and functions in SCA3 Ki150 model
Published in Frontiers in molecular neuroscience (24-03-2023)“…Spinocerebellar ataxia type 3 (SCA3/MJD) is a neurodegenerative disease caused by CAG expansion in mutant gene. The resulting PolyQ tract in mutant ataxin-3…”
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Storytelling i social selling jako metody grywalizacji andragogicznej podnoszącej wartość zrównoważonego rozwoju
Published in Przedsiębiorczość Edukacja (29-12-2022)“…Rentowna przedsiębiorczość, andragogiczna edukacja i pomysłowa grywalizacja wychowawcza to wartości, którym systemowo podporządkowano wskaźniki…”
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Sex affects N-homocysteinylation at lysine residue 212 of albumin in mice
Published in Scientific reports (25-02-2019)“…The modification of protein lysine residues by the thioester homocysteine (Hcy)-thiolactone has been implicated in cardiovascular and neurodegenerative…”
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Structural analysis and profiling of phenolic secondary metabolites of Mexican lupine species using LC–MS techniques
Published in Phytochemistry (Oxford) (01-08-2013)“…175 Isomeric and isobaric phenolic secondary metabolites of Mexican, North American and Mediterranean lupine species were annotated using CID/MS∗ experiments…”
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Identification of drought responsive proteins and related proteomic QTLs in barley
Published in Journal of experimental botany (09-05-2019)“…In barley, Rubisco activase, luminal binding protein, phosphoglycerate mutase, glutathione S-transferase, heat shock proteins, and enzymes involved in…”
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The Influence of Lead on Generation of Signalling Molecules and Accumulation of Flavonoids in Pea Seedlings in Response to Pea Aphid Infestation
Published in Molecules (Basel, Switzerland) (24-08-2017)“…The aim of this study was to investigate the effect of an abiotic factor, i.e., lead at various concentrations (low causing a hormesis effect and causing high…”
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Upregulation of hepatic autophagy under nutritional ketosis
Published in The Journal of nutritional biochemistry (01-07-2021)“…Many of the metabolic effects evoked by the ketogenic diet mimic the actions of fasting and the benefits of the ketogenic diet are often attributed to these…”
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Broad Influence of Mutant Ataxin-3 on the Proteome of the Adult Brain, Young Neurons, and Axons Reveals Central Molecular Processes and Biomarkers in SCA3/MJD Using Knock-In Mouse Model
Published in Frontiers in molecular neuroscience (17-06-2021)“…Spinocerebellar ataxia type 3 (SCA3/MJD) is caused by CAG expansion mutation resulting in a long polyQ domain in mutant ataxin-3. The mutant protein is a…”
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14
Obesity-associated deterioration of the hippocampus is partially restored after weight loss
Published in Brain, behavior, and immunity (01-08-2021)“…•Developmental obesity induced by a cafeteria diet changes the hippocampal proteome and impairs neurogenesis and cognition in adult rats.•Weight loss…”
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Proteomic and Structural Manifestations of Cardiomyopathy in Rat Models of Obesity and Weight Loss
Published in Frontiers in endocrinology (Lausanne) (24-02-2021)“…Obesity cardiomyopathy increases the risk of heart failure and death. Obesity is curable, leading to the restoration of the heart phenotype, but it is not…”
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Proteomic Profiling of Leukocytes Reveals Dysregulation of Adhesion and Integrin Proteins in Chronic Kidney Disease-Related Atherosclerosis
Published in Journal of proteome research (04-06-2021)“…A progressive loss of functional nephrons defines chronic kidney disease (CKD). Complications related to cardiovascular disease (CVD) are the principal causes…”
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Phloem exudate metabolic content reflects the response to water‐deficit stress in pea plants (Pisum sativum L.)
Published in The Plant journal : for cell and molecular biology (01-06-2021)“…Summary Drought stress impacts the quality and yield of Pisum sativum. Here, we show how short periods of limited water availability during the vegetative…”
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Serum Proteome Signature of Radiation Response: Upregulation of Inflammation-Related Factors and Downregulation of Apolipoproteins and Coagulation Factors in Cancer Patients Treated With Radiation Therapy—A Pilot Study
Published in International journal of radiation oncology, biology, physics (01-08-2015)“…Purpose Ionizing radiation affects the proteome of irradiated cells and tissue, yet data concerning changes induced during radiation therapy (RT) in human…”
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Serum Proteome Alterations in Human Cystathionine β-Synthase Deficiency and Ischemic Stroke Subtypes
Published in International journal of molecular sciences (25-06-2019)“…Ischemic stroke induces brain injury via thrombotic or embolic mechanisms involving large or small vessels. Cystathionine β-synthase deficiency (CBS), an…”
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Identification of Altered Developmental Pathways in Human Juvenile HD iPSC With 71Q and 109Q Using Transcriptome Profiling
Published in Frontiers in cellular neuroscience (18-01-2019)“…In Huntington disease (HD) subtle symptoms in patients may occur years or even decades prior to diagnosis. HD changes at a molecular level may begin as early…”
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