Search Results - "Marcus, Peter"

Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression by Peter, Marcus E.

“…Micro (mi)RNAs are emerging as important regulators of cellular differentiation, their importance underscored by the fact that they are often dysregulated…”
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Programmed cell death: Apoptosis meets necrosis by Peter, Marcus E

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CD95/Fas ligand induced toxicity by Haluck-Kangas, Ashley, Peter, Marcus E

“…The role of CD95/Fas ligand (CD95L/FasL) in the induction of CD95-mediated extrinsic apoptosis is well characterized. Trimerized, membrane-bound CD95L ligates…”
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Cancer kill code extension by Peter, Marcus E.

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 by Park, Sun-Mi, Gaur, Arti B, Lengyel, Ernst, Peter, Marcus E

“…Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic development, during which cells…”
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DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells? by Patel, Monal, Peter, Marcus E.

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Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis by Wang, Yinu, Zhao, Guangyuan, Condello, Salvatore, Huang, Hao, Cardenas, Horacio, Tanner, Edward J, Wei, JianJun, Ji, Yanrong, Li, Junjie, Tan, Yuying, Davuluri, Ramana V, Peter, Marcus E, Cheng, Ji-Xin, Matei, Daniela

“…Defining traits of platinum-tolerant cancer cells could expose new treatment vulnerabilities. Here, new markers associated with platinum-tolerant cells and…”
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The role of let-7 in cell differentiation and cancer by Boyerinas, Benjamin, Park, Sun-Mi, Hau, Annika, Murmann, Andrea E, Peter, Marcus E

“…MicroRNAs (miRNAs or miRs) are small noncoding RNAs capable of regulating gene expression at the translational level. Current evidence suggests that a…”
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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth by Nieman, Kristin M, Kenny, Hilary A, Penicka, Carla V, Ladanyi, Andras, Buell-Gutbrod, Rebecca, Zillhardt, Marion R, Romero, Iris L, Carey, Mark S, Mills, Gordon B, Hotamisligil, Gökhan S, Yamada, S Diane, Peter, Marcus E, Gwin, Katja, Lengyel, Ernst

“…Ovarian tumors preferentially metastasize to the omentum, a peritoneal fat layer. This report proposes that the reasons for this predilection stem from the…”
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Getting Write Into Therapy by Marcus, Peter H., PsyD

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MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer by Mitra, Anirban K, Zillhardt, Marion, Hua, Youjia, Tiwari, Payal, Murmann, Andrea E, Peter, Marcus E, Lengyel, Ernst

“…Cancer-associated fibroblasts (CAF) are a major constituent of the tumor stroma, but little is known about how cancer cells transform normal fibroblasts into…”
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Unfolding a death signal to treat rheumatoid arthritis by Peter, Marcus E., Bastings, Maartje M. C.

“…A pH-activatable DNA origami nanostructure with geometrically patterned CD95 ligands reverses symptoms in a mouse model of rheumatoid arthritis without…”
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Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing by Xu, Yilin, Gao, Xin D, Lee, Jae-Hyung, Huang, Huilin, Tan, Haiyan, Ahn, Jaegyoon, Reinke, Lauren M, Peter, Marcus E, Feng, Yue, Gius, David, Siziopikou, Kalliopi P, Peng, Junmin, Xiao, Xinshu, Cheng, Chonghui

“…Tumor metastasis remains the major cause of cancer-related death, but its molecular basis is still not well understood. Here we uncovered a splicing-mediated…”
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Genomics of Ovarian Cancer Progression Reveals Diverse Metastatic Trajectories Including Intraepithelial Metastasis to the Fallopian Tube by Eckert, Mark A, Pan, Shawn, Hernandez, Kyle M, Loth, Rachel M, Andrade, Jorge, Volchenboum, Samuel L, Faber, Pieter, Montag, Anthony, Lastra, Ricardo, Peter, Marcus E, Yamada, S Diane, Lengyel, Ernst

“…Accumulating evidence has supported the fallopian tube rather than the ovary as the origin for high-grade serous ovarian cancer (HGSOC). To understand the…”
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SPOROS: A pipeline to analyze DISE/6mer seed toxicity by Bartom, Elizabeth T, Kocherginsky, Masha, Paudel, Bidur, Vaidyanathan, Aparajitha, Haluck-Kangas, Ashley, Patel, Monal, O'Shea, Kaitlyn L, Murmann, Andrea E, Peter, Marcus E

“…microRNAs (miRNAs) are (18-22nt long) noncoding short (s)RNAs that suppress gene expression by targeting the 3' untranslated region of target mRNAs. This…”
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Identification of DISE-inducing shRNAs by monitoring cellular responses by Patel, Monal, Peter, Marcus E

“…Off-target effects (OTE) are an undesired side effect of RNA interference (RNAi) caused by partial complementarity between the targeting siRNA and mRNAs other…”
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mir-200c Regulates Induction of Apoptosis through CD95 by Targeting FAP-1 by Schickel, Robert, Park, Sun-Mi, Murmann, Andrea E., Peter, Marcus E.

“…Tumor progression shares many characteristics with the process of epithelial-to-mesenchymal transition (EMT). Cells that have undergone an EMT are known to…”
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Coordinated epigenetic repression of the miR‐200 family and miR‐205 in invasive bladder cancer by Wiklund, Erik D., Bramsen, Jesper B., Hulf, Toby, Dyrskjøt, Lars, Ramanathan, Ramshanker, Hansen, Thomas B., Villadsen, Sune B., Gao, Shan, Ostenfeld, Marie S., Borre, Michael, Peter, Marcus E., Ørntoft, Torben F., Kjems, Jørgen, Clark, Susan J.

“…MicroRNAs (miRNA) are small noncoding RNAs commonly deregulated in cancer. The miR‐200 family (miR‐200a, ‐200b, ‐200c, ‐141 and ‐429) and miR‐205 are…”
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Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation by Calvert, Andrea E., Chalastanis, Alexandra, Wu, Yongfei, Hurley, Lisa A., Kouri, Fotini M., Bi, Yingtao, Kachman, Maureen, May, Jasmine L., Bartom, Elizabeth, Hua, Youjia, Mishra, Rama K., Schiltz, Gary E., Dubrovskyi, Oleksii, Mazar, Andrew P., Peter, Marcus E., Zheng, Hongwu, James, C. David, Burant, Charles F., Chandel, Navdeep S., Davuluri, Ramana V., Horbinski, Craig, Stegh, Alexander H.

“…Oncogenic mutations in two isocitrate dehydrogenase (IDH)-encoding genes (IDH1 and IDH2) have been identified in acute myelogenous leukemia, low-grade glioma,…”
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Telehealth for psychiatry and mental healthcare can improve access and patient outcomes by Keuroghlian, Alex S., Marcus, Peter H., Neufeld, Jonathan, Phillips, Emily, Grasso, Chris, Wozniak, Janet R.

“…Use of telepsychiatry increased during the COVID-19 pandemic, resulting in greater access and the potential for improved care, although barriers to wider…”
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