Search Results - "Marcus, Maurer"

Differences and Similarities in the Mechanisms and Clinical Expression of Bradykinin-Mediated vs. Mast Cell–Mediated Angioedema by Maurer, Marcus, Magerl, Markus

“…Angioedema (AE), transient localized swelling due to extravasated fluid, is commonly classified as mast cell mediator-induced, bradykinin-mediated or of…”
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The role and relevance of mast cells in urticaria by Church, Martin K., Kolkhir, Pavel, Metz, Martin, Maurer, Marcus

“…Summary This review presents evidence that the skin mast cell, in particular the MCTC subtype, is the primary effector cell in urticaria. Mast cells are…”
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Predictors of treatment response in chronic spontaneous urticaria by Fok, Jie Shen, Kolkhir, Pavel, Church, Martin K., Maurer, Marcus

“…The current therapeutic algorithm for chronic spontaneous urticaria (CSU), endorsed by the international guideline, entails treatment escalation from…”
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Omalizumab for the treatment of chronic spontaneous urticaria: A meta-analysis of randomized clinical trials by Zhao, Zuo-Tao, MD, PhD, Ji, Chun-Mei, M Pharm, Yu, Wen-Jun, MD, Meng, Ling, M Pharm, Hawro, Tomasz, MD, Wei, Ji-Fu, PhD, Maurer, Marcus, MD

“…Background Chronic spontaneous urticaria (CSU) is defined by itchy hives, angioedema, or both for at least 6 weeks. Omalizumab, an anti-IgE antibody that…”
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Omalizumab is an effective and rapidly acting therapy in difficult-to-treat chronic urticaria: A retrospective clinical analysis by Metz, Martin, Ohanyan, Tatevik, Church, Martin K, Maurer, Marcus

“…Abstract Background Omalizumab (anti-IgE) therapy is effective and safe in chronic urticaria (CU) in placebo-controlled clinical trials but real life clinical…”
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Treatment of urticarial vasculitis: A systematic review by Kolkhir, Pavel, Grakhova, Maria, Bonnekoh, Hanna, Krause, Karoline, Maurer, Marcus

“…Urticarial vasculitis (UV) is a difficult-to-treat condition characterized by long-lasting urticarial rashes and histopathologic findings of leukocytoclastic…”
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Serum autoreactivity predicts time to response to omalizumab therapy in chronic spontaneous urticaria by Gericke, Janine, PhD, Metz, Martin, MD, Ohanyan, Tatevik, MD, Weller, Karsten, MD, Altrichter, Sabine, MD, Skov, Per Stahl, MD, Falkencrone, Sidsel, PhD, Brand, Janko, PhD, Kromminga, Arno, PhD, Hawro, Tomasz, MD, Church, Martin K., PhD, DSc, Maurer, Marcus, MD

“…The cutoff time of 8 days between fast and slow responders was chosen because it corresponds with the peak plasma level of omalizumab after its initial…”
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Epidemiology of Bradykinin-mediated angioedema: a systematic investigation of epidemiological studies by Aygören-Pürsün, Emel, Magerl, Markus, Maetzel, Andreas, Maurer, Marcus

“…Bradykinin-mediated angioedema (Bk-AE) can be life-threatening and requires specific targeted therapies. Knowledge of its epidemiology may help optimize its…”
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The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria by Zuberbier, Torsten, Abdul Latiff, Amir Hamzah, Abuzakouk, Mohamed, Aquilina, Susan, Asero, Riccardo, Baker, Diane, Ballmer‐Weber, Barbara, Bangert, Christine, Ben‐Shoshan, Moshe, Bernstein, Jonathan A., Bindslev‐Jensen, Carsten, Brockow, Knut, Brzoza, Zenon, Chong Neto, Herberto Jose, Church, Martin K., Criado, Paulo R., Danilycheva, Inna V., Dressler, Corinna, Ensina, Luis Felipe, Fonacier, Luz, Gaskins, Matthew, Gáspár, Krisztian, Gelincik, Aslı, Giménez‐Arnau, Ana, Godse, Kiran, Gonçalo, Margarida, Grattan, Clive, Grosber, Martine, Hamelmann, Eckard, Hébert, Jacques, Hide, Michihiro, Kaplan, Allen, Kapp, Alexander, Kessel, Aharon, Kocatürk, Emek, Kulthanan, Kanokvalai, Larenas‐Linnemann, Désirée, Lauerma, Antti, Leslie, Tabi A., Magerl, Markus, Makris, Michael, Meshkova, Raisa Y., Metz, Martin, Micallef, Daniel, Mortz, Charlotte G., Nast, Alexander, Oude‐Elberink, Hanneke, Pawankar, Ruby, Pigatto, Paolo D., Ratti Sisa, Hector, Rojo Gutiérrez, María Isabel, Saini, Sarbjit S., Schmid‐Grendelmeier, Peter, Sekerel, Bulent E., Siebenhaar, Frank, Siiskonen, Hanna, Soria, Angele, Staubach‐Renz, Petra, Stingeni, Luca, Sussman, Gordon, Szegedi, Andrea, Thomsen, Simon Francis, Vadasz, Zahava, Vestergaard, Christian, Wedi, Bettina, Zhao, Zuotao, Maurer, Marcus

“…This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of…”
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Development and validation of the Urticaria Control Test: A patient-reported outcome instrument for assessing urticaria control by Weller, Karsten, MD, Groffik, Adriane, MD, Church, Martin K., PhD, DSc, Hawro, Tomasz, MD, Krause, Karoline, MD, Metz, Martin, MD, Martus, Peter, PhD, Casale, Thomas B., MD, Staubach, Petra, MD, Maurer, Marcus, MD

“…Background Chronic urticaria is a frequent and debilitating skin disease. Its symptoms commonly fluctuate considerably from day to day. As of yet, the only…”
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Autoimmune comorbidity in chronic spontaneous urticaria: A systematic review by Kolkhir, Pavel, Borzova, Elena, Grattan, Clive, Asero, Riccardo, Pogorelov, Dmitry, Maurer, Marcus

“…Numerous autoimmune diseases (AIDs) have been linked to chronic spontaneous urticaria (CSU). Here, we provide the first extensive and comprehensive evaluation…”
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Omalizumab is Effective in Cold Urticaria - Results of a Randomized, Placebo Controlled Trial by Metz, Martin, M.D, Schütz, Andrea, M.D, Weller, Karsten, M.D, Gorczyza, Marina, M.D, Zimmer, Sebastian, M.D, Staubach, Petra, M.D, Merk, Hans F., M.D, Maurer, Marcus, M.D

“…Cold urticaria is a potentially life-threatening disease and placebo treatment of patients does not provide protection from cold-induced systemic reactions…”
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Autoimmune chronic spontaneous urticaria: What we know and what we do not know by Kolkhir, Pavel, MD, Church, Martin K., PhD, Dsc, Weller, Karsten, MD, Metz, Martin, MD, Schmetzer, Oliver, MD, Maurer, Marcus, MD

“…Chronic spontaneous urticaria (CSU) is a mast cell–driven skin disease characterized by the recurrence of transient wheals, angioedema, or both for more than…”
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The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update by Maurer, Marcus, Magerl, Markus, Betschel, Stephen, Aberer, Werner, Ansotegui, Ignacio J., Aygören‐Pürsün, Emel, Banerji, Aleena, Bara, Noémi‐Anna, Boccon‐Gibod, Isabelle, Bork, Konrad, Bouillet, Laurence, Boysen, Henrik Balle, Brodszki, Nicholas, Busse, Paula J., Bygum, Anette, Caballero, Teresa, Cancian, Mauro, Castaldo, Anthony, Cohn, Danny M., Csuka, Dorottya, Farkas, Henriette, Gompels, Mark, Gower, Richard, Grumach, Anete S., Guidos‐Fogelbach, Guillermo, Hide, Michihiro, Kang, Hye‐Ryun, Kaplan, Allen Phillip, Katelaris, Constance, Kiani‐Alikhan, Sorena, Lei, Wei‐Te, Lockey, Richard, Longhurst, Hilary, Lumry, William R., MacGinnitie, Andrew, Malbran, Alejandro, Martinez Saguer, Inmaculada, Matta, Juan José, Nast, Alexander, Nguyen, Dinh, Nieto‐Martinez, Sandra A., Pawankar, Ruby, Peter, Jonathan, Porebski, Grzegorz, Prior, Nieves, Reshef, Avner, Riedl, Marc, Ritchie, Bruce, Rafique Sheikh, Farrukh, Smith, William B., Spaeth, Peter J., Stobiecki, Marcin, Toubi, Elias, Varga, Lilian Agnes, Weller, Karsten, Zanichelli, Andrea, Zhi, Yuxiang, Zuraw, Bruce, Craig, Timothy

“…Hereditary angioedema (HAE) is a rare and disabling disease for which early diagnosis and effective therapy are critical. This revision and update of the…”
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Chronic urticaria and the pathogenic role of mast cells by Elieh-Ali-Komi, Daniel, Metz, Martin, Kolkhir, Pavel, Kocatürk, Emek, Scheffel, Jörg, Frischbutter, Stefan, Terhorst-Molawi, Dorothea, Fox, Lena, Maurer, Marcus

“…The signs and symptoms of chronic urticaria (CU) are caused by the activation and degranulation of skin mast cells (MCs). Recent studies have added to our…”
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Chronic Spontaneous Urticaria: The Role and Relevance of Autoreactivity, Autoimmunity, and Autoallergy by Asero, Riccardo, Ferrer, Marta, Kocaturk, Emek, Maurer, Marcus

“…Chronic spontaneous urticaria (CSU) is a frequent and often severely disabling disease. A large number of studies were performed during the last 2 decades to…”
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Mas-related G protein–coupled receptor X2 and its activators in dermatologic allergies by Kühn, Helen, Kolkhir, Pavel, Babina, Magda, Düll, Miriam, Frischbutter, Stefan, Fok, Jie Shen, Jiao, Qingqing, Metz, Martin, Scheffel, Jörg, Wolf, Katharina, Kremer, Andreas E., Maurer, Marcus

“…The Mas-related G protein–coupled receptor X2 (MRGPRX2) is a multiligand receptor responding to various exogenous and endogenous stimuli. Being highly…”
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An open-label, proof-of-concept study of lirentelimab for antihistamine-resistant chronic spontaneous and inducible urticaria by Altrichter, Sabine, Staubach, Petra, Pasha, Malika, Singh, Bhupinder, Chang, Alan T., Bernstein, Jonathan A., Rasmussen, Henrik S., Siebenhaar, Frank, Maurer, Marcus

“…Chronic urticaria (CU) is a debilitating mast cell–driven disease, often refractory to standard therapy (ie, antihistamines). Lirentelimab, an anti–sialic…”
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Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria by Maurer, Marcus, Rosén, Karin, Hsieh, Hsin-Ju, Saini, Sarbjit, Grattan, Clive, Gimenéz-Arnau, Ana, Agarwal, Sunil, Doyle, Ramona, Canvin, Janice, Kaplan, Allen, Casale, Thomas

“…This large, randomized, placebo-controlled trial showed the efficacy of omalizumab, an injectable anti–IgE humanized monoclonal antibody, in the treatment of…”
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Efficacy and safety of canakinumab in Schnitzler syndrome: A multicenter randomized placebo-controlled study by Krause, Karoline, MD, Tsianakas, Athanasios, MD, Wagner, Nicola, MD, Fischer, Jörg, MD, Weller, Karsten, MD, Metz, Martin, MD, Church, Martin K., PhD, Maurer, Marcus, MD

“…Background Schnitzler syndrome is an adult-onset autoinflammatory disease characterized by urticarial exanthema and monoclonal gammopathy accompanied by…”
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