Search Results - "Marcus, J P"

Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly by Andreux, Pénélope A., van Diemen, Marcus P. J., Heezen, Maxime R., Auwerx, Johan, Rinsch, Chris, Groeneveld, Geert Jan, Singh, Anurag

“…Aging is accompanied by a gradual decline in both muscle mass and strength over time, which can eventually lead to pathologies, such as frailty and sarcopenia…”
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Examining Tweet Content and Engagement of Users With Tweets About Hikikomori in Japanese: Mixed Methods Study of Social Withdrawal by Pereira-Sanchez, Victor, Alvarez-Mon, Miguel Angel, Horinouchi, Toru, Kawagishi, Ryo, Tan, Marcus P J, Hooker, Elizabeth R, Alvarez-Mon, Melchor, Teo, Alan R

“…Hikikomori is a form of severe social withdrawal that is particularly prevalent in Japan. Social media posts offer insight into public perceptions of mental…”
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Mitochondrial function, grip strength, and activity are related to recovery of mobility after a total knee arthroplasty by Diemen, Marcus P. J., Ziagkos, Dimitrios, Kruizinga, Matthijs D., Bénard, Menno R., Lambrechtse, Philip, Jansen, Joris A. J., Snoeker, Barbara A. M., Gademan, Maaike G. J., Cohen, Adam F., Nelissen, Rob G. H. H., Groeneveld, Geert Jan

“…Low muscle quality and a sedentary lifestyle are indicators for a slow recovery after a total knee arthroplasty (TKA). Mitochondrial function is an important…”
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International experience of hikikomori (prolonged social withdrawal) and its relevance to psychiatric research by Tan, Marcus P. J., Lee, William, Kato, Takahiro A.

“…When prolonged social withdrawal was first described in Japan as ‘hikikomori’, many studies examining its etiology suggested it to be related to factors unique…”
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Publisher Correction: Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly by Andreux, Pénélope A., van Diemen, Marcus P. J., Heezen, Maxime R., Auwerx, Johan, Rinsch, Chris, Groeneveld, Geert Jan, Singh, Anurag

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Bleeding Control in Palliative Care Patients With the Help of Tranexamic Acid by Geist, Marcus J. P., Kessler, Jens, Frankenhauser, Susanne, Bardenheuer, Hubert J.

“…Background: Persistent bleeding is a common reason for admitting patients with advanced cancer to a palliative care unit. Several reports show a successful…”
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Induction of voriconazole metabolism by rifampin in a patient with acute myeloid leukemia: importance of interdisciplinary communication to prevent treatment errors with complex medications by Geist, Marcus J P, Egerer, Gerlinde, Burhenne, Jürgen, Riedel, Klaus-Dieter, Mikus, Gerd

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Minor contribution of cytochrome P450 3A activity on fentanyl exposure in palliative care cancer patients by Geist, Marcus J. P., Ziesenitz, Victoria C., Bardenheuer, Hubert J., Burhenne, Juergen, Skopp, Gisela, Mikus, Gerd

“…Transdermal fentanyl is widely used to control pain in cancer patients. The high pharmacokinetic variability of fentanyl is assumed to be due to cytochrome…”
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A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels by Marcus, John P., Green, Jodie L., Goulter, Ken C., Manners, John M.

“…Summary A new family of antimicrobial peptides has been discovered in Macadamia integrifolia. The first member of this new family to be purified from nut…”
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Safety, pharmacokinetics and pharmacodynamics of SBT‐020 in patients with early stage Huntington's disease, a 2‐part study by Diemen, Marcus P.J., Hart, Ellen P., Abbruscato, Anthony, Mead, Liz, Beelen, Ilse, Bergheanu, Sandrin C., Hameeteman, Pieter W., Coppen, Emma, Winder, Jessica Y., Moerland, Matthijs, Kan, Hermien, Grond, Jeroen, Webb, Andrew, Roos, Raymund A.C., Groeneveld, Geert Jan

“…Aims Huntington's disease (HD) is a neurodegenerative disease with cognitive, motor and psychiatric symptoms. Toxic accumulation of misfolded mutant huntingtin…”
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Decreased Cytochrome P450 3A activity in palliative patients with haematological diseases: Potential impact on supportive drug therapies by Geist, Marcus J. P., Siller, Nelly, Egerer, Gerlinde, Bardenheuer, Hubert, Burhenne, Juergen, Mikus, Gerd

“…Cytochrome P450 3A (CYP3A) is the most relevant drug‐metabolizing enzyme in human beings involved in the elimination of about 50% of the marketed drugs…”
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Steady-state pharmacokinetics and metabolism of voriconazole in patients by Geist, Marcus J P, Egerer, Gerlinde, Burhenne, Jürgen, Riedel, Klaus-Dieter, Weiss, Johanna, Mikus, Gerd

“…Voriconazole exhibits non-linear pharmacokinetics in adults and is said to be mainly metabolized by CYP2C19 and CYP3A4 to voriconazole-N-oxide. The aim of this…”
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Impact of patient education on plasma concentrations and effectiveness of posaconazole oral suspension under clinical conditions by Geist, Marcus J. P., Egerer, Gerlinde, Mikus, Gerd, Blank, Antje, Hohmann, Nicolas, Heinz, Werner J., Carls, Alexandra

“…Posaconazole prophylaxis is recommended for patients with acute myeloid leukaemia during induction chemotherapy. Although a tablet formulation with better oral…”
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In Vivo CYP3A Activity in Palliative Care Patients: Study Protocol for a Single Arm Prospective Trial by Geist, Marcus J P, Bardenheuer, Hubert J, Burhenne, Jürgen, Mikus, Gerd

“…Drug interactions are a common cause for escalation of debilitating symptoms in palliative care patients. CYP3A is the most relevant CYP enzyme in humans…”
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Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study by van Diemen, Marcus P.J., Berends, Cécile L., Akram, Naila, Wezel, Joep, Teeuwisse, Wouter M., Mik, Bert G., Kan, Hermien E., Webb, Andrew, Beenakker, Jan Willem M., Groeneveld, Geert Jan

“…Proof-of-pharmacology models to study compounds in healthy subjects offer multiple advantages. Simvastatin is known to induce mitochondrial dysfunction at…”
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A Call for a Rational Polypharmacy Policy: International Insights From Psychiatrists by Nakagami, Yukako, Hayakawa, Kohei, Horinouchi, Toru, Pereira-Sanchez, Victor, Tan, Marcus P.J., Park, Seon-Cheol, Park, Yong Chon, Moon, Seok Woo, Choi, Tae Young, Avasthi, Ajit, Grover, Sandeep, Kallivayalil, Roy Abraham, Rai, Yugesh, Shalbafan, Mohammadreza, Chongsuksiri, Pavita, Udomratn, Pichet, Kathriarachchi, Samudra T., Xiang, Yu-Tao, Sim, Kang, Javed, Afzal, Chong, Mian-Yoon, Tan, Chay-Hoon, Lin, Shih-Ku, Inada, Toshiya, Murai, Toshiya, Kanba, Shigenobu, Sartorius, Norman, Shinfuku, Naotaka, Kato, Takahiro A.

“…Objective Recently, rational polypharmacy approaches have been proposed, regardless of the lower risk and cost of monotherapy. Considering monotherapy as…”
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Two-Stage Revision of an Infected Total Hip Arthroplasty: A Follow-up of 136 Patients by van Diemen, Marcus P.J., Colen, Sascha, Dalemans, Alain A.R., Stuyck, Jose, Mulier, Michiel

“…Background and purpose Periprosthetic infection of a total hip arthroplasty (THA) is commonly treated with a two-stage revision procedure. After resection of…”
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Safety of voriconazole in a patient with CYP2C92/CYP2C92 genotype by Geist, Marcus J P, Egerer, Gerlinde, Burhenne, Jürgen, Mikus, Gerd

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Gender Biases Toward People With Difficulty in Balancing Work and Family Due to ADHD: Two Case Vignette Randomized Studies Featuring Japanese Laypersons and Psychiatrists by So, Ryuhei, Nakashima, Misuzu, Pei-Chen Chang, Jane, P J Tan, Marcus, Kayano, Ryoma, Okumura, Yasuyuki, Horinouchi, Toru, Ii, Toshitaka, Kuroki, Toshihide, Akiyama, Tsuyoshi

“…Objective The gender gap in labor force participation is likely larger in adults with attention deficit hyperactivity disorder (ADHD) than that in the general…”
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Threonine formation via the coupled activity of 2-amino-3-ketobutyrate coenzyme A lyase and threonine dehydrogenase by MARCUS, J. P, DEKKER, E. E

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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