Search Results - "Marcus, David J"
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The NimStim set of facial expressions: Judgments from untrained research participants
Published in Psychiatry research (15-08-2009)“…Abstract A set of face stimuli called the NimStim Set of Facial Expressions is described. The goal in creating this set was to provide facial expressions that…”
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Endocannabinoid signalling modulates susceptibility to traumatic stress exposure
Published in Nature communications (28-03-2017)“…Stress is a ubiquitous risk factor for the exacerbation and development of affective disorders including major depression and posttraumatic stress disorder…”
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Where ketamine and dopamine collide
Published in eLife (17-06-2021)“…Ketamine strengthens connections between two brain regions that are involved in the production and regulation of dopamine, which may explain how the drug can…”
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Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-2019)“…Scaffold proteins tether and orient components of a signaling cascade to facilitate signaling. Although much is known about how scaffolds colocalize signaling…”
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Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption
Published in PloS one (20-04-2017)“…We recently characterized S426A/S430A mutant mice expressing a desensitization-resistant form of the CB1 receptor. These mice display an enhanced response to…”
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Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic
Published in PloS one (08-08-2016)“…Multiple lines of evidence implicate the endocannabinoid signaling system in the modulation of metabolic disease. Genetic or pharmacological inactivation of…”
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Oculomotor and manual indexes of incidental and intentional spatial sequence learning during middle childhood and adolescence
Published in Journal of experimental child psychology (01-02-2007)“…The goal of this study was to examine incidental and intentional spatial sequence learning during middle childhood and adolescence. We tested four age groups…”
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Regulation of cognitive resources during sustained attention and working memory in 10-year-olds and adults
Published in Psychophysiology (01-01-2007)“…We examined differences between 10‐year‐olds and young adults in resource recruitment and regulation during tasks of sustained attention and spatial working…”
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Optical Approaches for Investigating Neuromodulation and G Protein-Coupled Receptor Signaling
Published in Pharmacological reviews (01-11-2023)“…Despite the fact that roughly 40% of all US Food and Drug Administration (FDA)-approved pharmacological therapeutics target G protein-coupled receptors…”
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Body Image, Self-perception, and Satisfaction Among Girls With Turner Syndrome: A Prospective Cross-sectional Study
Published in The journal of clinical endocrinology and metabolism (24-03-2022)“…Delayed puberty and short stature in girls with Turner syndrome (TS) can lead to low body image, self-esteem, and satisfaction. We aimed to evaluate body…”
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An endocannabinoid-regulated basolateral amygdala-nucleus accumbens circuit modulates sociability
Published in The Journal of clinical investigation (01-04-2020)“…Deficits in social interaction (SI) are a core symptom of autism spectrum disorders (ASDs); however, treatments for social deficits are notably lacking…”
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Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening
Published in Neuron (Cambridge, Mass.) (18-03-2020)“…Functional coupling between the amygdala and the dorsomedial prefrontal cortex (dmPFC) has been implicated in the generation of negative affective states;…”
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Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement
Published in Nature neuroscience (01-10-2021)“…The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is relatively understudied, and therefore its role in…”
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c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner
Published in Neuropharmacology (01-03-2020)“…Tolerance to the antinociceptive effects of cannabinoids represents a significant limitation to their clinical use in managing chronic pain. Tolerance likely…”
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ProSAAS‐derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine
Published in Journal of neurochemistry (01-11-2017)“…To identify neuropeptides that are regulated by cocaine, we used a quantitative peptidomic technique to examine the relative levels of neuropeptides in several…”
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Oculomotor evidence of sequence learning on the serial reaction time task
Published in Memory & cognition (01-03-2006)“…Manual and oculomotor measures of sequence learning were examined on the serial reaction time (SRT) task Participants were assigned into four groups differing…”
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A locus coeruleus to dentate gyrus noradrenergic circuit modulates aversive contextual processing
Published in Neuron (Cambridge, Mass.) (07-07-2021)“…Dysregulation in contextual processing is believed to affect several forms of psychopathology, such as post-traumatic stress disorder (PTSD). The dentate gyrus…”
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Tolerance to the Antinociceptive Effects of Chronic Morphine Requires C-Jun N-Terminal Kinase
Published in Molecular pain (12-06-2015)“…Background Morphine and fentanyl are opioid analgesics in wide clinical use that act through the μ-opioid receptor (MOR). However, one limitation of their…”
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Attention allocation in the dual-task paradigm as measured through behavioral and psychophysiological responses
Published in Psychophysiology (01-03-2004)“…We investigated attention allocation in a dual‐task paradigm using behavioral and pupillary measures. We used an auditory digit span (DS) and a simple visual…”
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