Search Results - "Marcus, Danielle"

Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody by Stewart, Ross, Morrow, Michelle, Hammond, Scott A, Mulgrew, Kathy, Marcus, Danielle, Poon, Edmund, Watkins, Amanda, Mullins, Stefanie, Chodorge, Matthieu, Andrews, John, Bannister, David, Dick, Emily, Crawford, Nicola, Parmentier, Julie, Alimzhanov, Marat, Babcook, John S, Foltz, Ian N, Buchanan, Andrew, Bedian, Vahe, Wilkinson, Robert W, McCourt, Matthew

“…Programmed cell-death 1 ligand 1 (PD-L1) is a member of the B7/CD28 family of proteins that control T-cell activation. Many tumors can upregulate expression of…”
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Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery by Mosely, Suzanne I S, Prime, John E, Sainson, Richard C A, Koopmann, Jens-Oliver, Wang, Dennis Y Q, Greenawalt, Danielle M, Ahdesmaki, Miika J, Leyland, Rebecca, Mullins, Stefanie, Pacelli, Luciano, Marcus, Danielle, Anderton, Judith, Watkins, Amanda, Coates Ulrichsen, Jane, Brohawn, Philip, Higgs, Brandon W, McCourt, Matthew, Jones, Hazel, Harper, James A, Morrow, Michelle, Valge-Archer, Viia, Stewart, Ross, Dovedi, Simon J, Wilkinson, Robert W

“…Murine syngeneic tumor models are critical to novel immuno-based therapy development, but the molecular and immunologic features of these models are still not…”
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Abstract LB-158: MEDI4736: Delivering effective blockade of immunosupression to enhance tumour rejection: Monoclonal antibody discovery and preclinical development by Stewart, Ross A., Morrow, Michelle, Chodorge, Matthieu, Marcus, Danielle, Boyle, Melanie, Mulgrew, Kathy, Hammond, Scott, Wang, Suping, Alimzhanov, Marat, Robbins, Paul, Lanning, Karen, Bedian, Vahe, McCourt, Matthew, Lo, Mathew

“…Abstract Cancerous cells emerge within the body following accumulation of deleterious genetic mutations. These mutations alter the phenotype of a cancer cell…”
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