Search Results - "Marcum, J A"

The Origin of the Dispute over the Discovery of Heparin by MARCUM, JAMES A.

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Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan by Marcum, J A, Atha, D H, Fritze, L M, Nawroth, P, Stern, D, Rosenberg, R D

“…Cloned bovine aortic endothelial cells were cultured with [35S]Na2SO4 and proteolyzed extensively with papain. Radiolabeled heparan sulfate was isolated by…”
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Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells by KOJIMA, T, LEONE, C. W, MARCHILDON, G. A, MARCUM, J. A, ROSENBERG, R. D

“…We have isolated heparan sulfate proteoglycans (HSPGs) from cloned rat microvascular endothelial cells using a combination of ion-exchange chromatography,…”
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Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium by Marcum, J A, McKenney, J B, Rosenberg, R D

“…We have examined the role of heparinlike molecules in the regulation of coagulation by perfusing rat hindquarters with purified human thrombin and with its…”
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The Development of Heparin in Toronto by MARCUM, JAMES A.

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Heparinlike molecules with anticoagulant activity are synthesized by cultured endothelial cells by Marcum, J A, Rosenberg, R D

“…Cultured microvascular endothelial cells isolated from rat epididymal fat pads produce glycosaminoglycans that accelerate thrombin-antithrombin complex…”
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Defending the Priority of 'Remarkable Researches': The Discovery of Fibrin Ferment by Marcum, James A.

“…At times scientists manipulate their community's perception of scientific discoveries. The following case study illustrates the extent to which a community's…”
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Anticoagulantly active heparin-like molecules from vascular tissue by Marcum, James A, Rosenberg, Robert D

“…Mucopolysaccharides were isolated from calf cerebral microvasculature and calf aorta. The only complex carbohydrates that exhibited anticoagulant activity were…”
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Anticoagulantly active heparan sulfate proteoglycan and the vascular endothelium by Marcum, J A, Rosenberg, R D

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Anticoagulantly active heparin-like molecules from mast cell-deficient mice by Marcum, J A, McKenney, J B, Galli, S J, Jackman, R W, Rosenberg, R D

“…To assess the contribution of mast cells to the maintenance of blood fluidity, the hindlimb vasculature of mast cell-deficient mice (W/Wv) and littermates…”
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Microvascular heparin-like species with anticoagulant activity by Marcum, J A, Fritze, L, Galli, S J, Karp, G, Rosenberg, R D

“…Calf microvasculature was isolated from retina and cerebral gray matter. These preparations contained 0.048-0.060 U of heparin-like anticoagulant activity per…”
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Mast Cell Clones: A Model for the Analysis of Cellular Maturation by Galli, Stephen J., Dvorak, Ann M., Marcum, James A., Ishizaka, Teruko, Nabel, Gary, Simonian, Harout Der, Pyne, Kathryn, Goldin, Jerold M., Rosenberg, Robert D., Cantor, Harvey, Dvorak, Harold F.

“…Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other…”
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Heparin inhibition of endotoxin-dependent Limulus amebocyte lysate coagulation by Marcum, J A, Levin, J

“…Addition of commercial heparin to preparations of the coagulation system obtained by hypotonic lysis of Limulus amebocytes, prior to the addition of endotoxin…”
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Interaction of Factor XIa and Antithrombin in the Presence and Absence of Heparin by Beeler, David L., Marcum, James A., Schiffman, Sandra, Rosenberg, Robert D.

“…We have studied the interaction between purified human factor XIa and antithrombin in the presence and absence of well-characterized preparations of heparin…”
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Distribution of biglycan and its propeptide form in rat and bovine aortic tissue by Yeo, T K, Torok, M A, Kraus, H L, Evans, S A, Zhou, Y, Marcum, J A

“…The matrix proteoglycan biglycan was identified in bovine and rat aortic tissue by Western blot analysis and by immunohistochemistry, using polyclonal…”
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Anticoagulantly active heparin from clam (Mercenaria mercenaria) by Jordan, R E, Marcum, J A

“…Heparin was isolated from Mercenaria mercenaria by ion-exchange chromatography and was fractionated into two distinct populations with immobilized…”
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The Role of Emotions in Clinical Reasoning and Decision Making by MARCUM, James A

“…What role, if any, should emotions play in clinical reasoning and decision making? Traditionally, emotions have been excluded from clinical reasoning and…”
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Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells by DVORAK, A. M, GALLI, S. J, DVORAK, H. F, MARCUM, J. A, NABEL, G, DER SIMONIAN, H, GOLDIN, J, MONAHAN, R. A, PYNE, K, CANTOR, H, ROSENBERG, R. D

“…We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform…”
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cDNA sequence for bovine biglycan (PGI) protein core by Torok, M A, Evans, S A, Marcum, J A

“…The nucleotide sequence of the protein core for bovine aortic smooth muscle cell biglycan was determined using recombinant DNA technology. Analysis of the…”
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The role of tryptophan residues in heparin-antithrombin interactions by Karp, G I, Marcum, J A, Rosenberg, R D

“…A single tryptophan residue on antithrombin has been modified with dimethyl-(2-hydroxy-5-nitrobenzyl)sulfonium bromide. This alteration led to a 500-fold…”
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