Search Results - "Marcu, Loredana"

Developments on tumour site-specific chrono-oncology towards personalised treatment by Marcu, Loredana G.

“…Research into chronotherapy has seen notable developments over the past decades, with a clear focus on the identification of circadian clock genes as potential…”
Get full text

Circadian rhythm-based cancer therapy in randomised clinical trials by Marcu, Loredana G

“…Since the 2017 Nobel Prize awarded to J. Hall, M. Rosbash and M.W. Young for their discoveries of molecular mechanisms behind the biological clock, circadian…”
Get full text

Correlations between patient-specific parameters and dosimetric indices for personalized breast cancer radiotherapy by Costin, Ioana-Claudia, Marcu, Loredana G.

“…Treatment planning parameters in radiotherapy are key elements that dictate the success of treatment outcome. While some parameters are commonly evaluated…”
Get full text

How much is too much? Systematic review of cumulative doses from radiological imaging and the risk of cancer in children and young adults by Marcu, Loredana G., Chau, Minh, Bezak, Eva

“…[Display omitted] •Literature on risks of cancer following paediatric/young adult imaging was reviewed.•Cancer risks post chest CT exposure decrease with…”
Get full text

Gender and Sex-Related Differences in Normal Tissue Effects Induced by Platinum Compounds by Marcu, Loredana G

“…Gender medicine in the field of oncology is an under-researched area, despite the existing evidence towards gender-dependent response to therapy and…”
Get full text

Global comparison of targeted alpha vs targeted beta therapy for cancer: In vitro, in vivo and clinical trials by Marcu, Loredana, Bezak, Eva, Allen, Barry J.

“…•Disseminated disease is the primary cause of cancer death.•Targeted cancer therapy is successful in the management of many intractable cancers.•Short ranged,…”
Get full text

Cannot Target What Cannot Be Seen: Molecular Imaging of Cancer Stem Cells by Marcu, Loredana G, Moghaddasi, Leyla, Bezak, Eva

“…Cancer stem cells are known to play a key role in tumour development, proliferation, and metastases. Their unique properties confer resistance to therapy,…”
Get full text

Gender-dependent radiotherapy: The next step in personalised medicine? by De Courcy, Louis, Bezak, Eva, Marcu, Loredana G.

“…•Research shows small but significant difference in radiation response between sexes.•Difference in inflammatory response, polymorphism, oestrogen are few…”
Get full text

COVID-19 vaccination rates of medical physicists throughout Europe by Marcu, Loredana G.

Get full text

Qualitative and quantitative evaluation of the role of CBCT in rectal cancer radiotherapy by Catona, Geanina-Mirela, Marcu, Loredana G.

“…Verifying patients' position and internal anatomical changes are important steps in the radiotherapy of rectal cancer. Cone Beam Computed Tomography (CBCT) is…”
Get full text

Radiobiological and Treatment-Related Aspects of Spatially Fractionated Radiotherapy by Moghaddasi, Leyla, Reid, Paul, Bezak, Eva, Marcu, Loredana G

“…The continuously evolving field of radiotherapy aims to devise and implement techniques that allow for greater tumour control and better sparing of critical…”
Get full text

The Promise of Novel Biomarkers for Head and Neck Cancer from an Imaging Perspective by Marcu, Loredana G, Reid, Paul, Bezak, Eva

“…It is an agreed fact that overall survival among head and neck cancer patients has increased over the last decade. Several factors however, are still held…”
Get full text

Cancer stem cells as therapeutic targets of pancreatic cancer by Marcu, Loredana G.

Get full text

Cardio-oncology concerns in radiotherapy: Heart and cardiac substructure toxicities from modern delivery techniques by Costin, Ioana-Claudia, Cinezan, Corina, Marcu, Loredana G.

“…Cardio-oncology is lately gaining more attention due to radiation-induced cardiac events reported by a very large number of studies. In view of this, the…”
Get full text

Future treatment directions for HPV-associated head and neck cancer based on radiobiological rationale and current clinical evidence by Marcu, Loredana G

“…Highlights • HPV status is a new variable in the equation of head and neck cancer treatment. • HPV+ oropharyngeal cancer exhibits different biological…”
Get full text

Opportunities in Cancer Therapies: Deciphering the Role of Cancer Stem Cells in Tumour Repopulation by Marcu, Loredana G, Dell'Oro, Mikaela, Bezak, Eva

“…Tumour repopulation during treatment is a well acknowledged yet still challenging aspect of cancer management. The latest research results show clear evidence…”
Get full text

Is there a dosimetric advantage of volumetric modulated arc therapy over intensity modulated radiotherapy in head and neck cancer? by Buciuman, Nikolett, Marcu, Loredana G.

“…Objective A planning study was performed to evaluate dosimetric differences between intensity modulated radiation therapy (IMRT) and volumetric modulated arc…”
Get full text

Patient and treatment-related factors that influence dose to heart and heart substructures in left-sided breast cancer radiotherapy by Costin, Ioana-Claudia, Marcu, Loredana G.

“…[Display omitted] •Heart and cardiac substructure dosimetry are essential in left-sided breast cancer.•The number of beams used for treatment planning impacts…”
Get full text

The role of hypofractionated radiotherapy in the management of head and neck cancer – a modelling approach by Marcu, Loredana G., Marcu, David

“…•The role of hypofractionated radiotherapy for head & neck cancer is not elucidated.•In silico modelling can assist to identify gaps in research.•Hypoxic and…”
Get full text

Dosimetric evaluation of intensity modulated photon versus proton reirradiation of head and neck cancer by Buciuman, Nikolett, Dasu, Alexandru, Marcu, Loredana G.

“…•Reirradiation of head & neck cancer is challenging irrespective of radiation quality.•A dosimetric pilot study was conducted on proton vs photon…”
Get full text