Search Results - "Marcos, C"
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Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?
Published in Nutrients (08-11-2019)“…Leptin, a hormone that is capable of effectively reducing food intake and body weight, was initially considered for use in the treatment of obesity. However,…”
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Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study
Published in The Lancet infectious diseases (01-06-2016)“…Summary Background The incidence of microcephaly in Brazil in 2015 was 20 times higher than in previous years. Congenital microcephaly is associated with…”
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Echolocation characteristics of franciscana dolphins (Pontoporia blainvillei)
Published in Marine mammal science (01-07-2021)Get full text
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An eosimiid primate of South Asian affinities in the Paleogene of Western Amazonia and the origin of New World monkeys
Published in Proceedings of the National Academy of Sciences - PNAS (11-07-2023)“…Recent fossil discoveries in Western Amazonia revealed that two distinct anthropoid primate clades of African origin colonized South America near the…”
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Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
Published in Science (American Association for the Advancement of Science) (24-12-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the emergence of variants, including the B.1.617.2 (Delta) variant of…”
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Leptin resistance in obesity: An epigenetic landscape
Published in Life sciences (1973) (01-11-2015)“…Leptin is an adipocyte-secreted hormone that inhibits food intake and stimulates energy expenditure through interactions with neuronal pathways in the brain,…”
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Simplified 2,4-dinitrophenylhydrazine spectrophotometric assay for quantification of carbonyls in oxidized proteins
Published in Analytical biochemistry (01-08-2014)“…This work proposes a modification of the 2,4-dinitrophenylhydrazine (DNPH) spectrophotometric assay commonly used to evaluate the concentration of carbonyl…”
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Reproductive parameters of franciscana dolphins (Pontoporia blainvillei) of Southeastern Brazil
Published in Marine mammal science (01-10-2020)“…Reproductive parameters of 168 franciscana dolphins, Pontoporia blainvillei (73 females and 95 males) incidentally caught (n = 163) or stranded (n = 5) between…”
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A study about management of drugs for leprosy patients under medical monitoring: A solution based on AHP-Electre decision-making methods
Published in PloS one (13-02-2023)“…Leprosy, also known as Hansen's, is one of the listed neglected tropical diseases as a major health problem global. Treatment is one of the main alternatives,…”
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De novo design of modular and tunable protein biosensors
Published in Nature (London) (18-03-2021)“…Naturally occurring protein switches have been repurposed for the development of biosensors and reporters for cellular and clinical applications 1 . However,…”
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The CD4:CD8 ratio is associated with markers of age‐associated disease in virally suppressed HIV‐infected patients with immunological recovery
Published in HIV medicine (01-01-2014)“…Objectives Inversion of the CD4:CD8 ratio (< 1) has been identified as a hallmark of inmmunosenescence and an independent predictor of mortality in the general…”
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Germline-encoded specificities and the predictability of the B cell response
Published in PLoS pathogens (25-08-2023)“…Antibodies result from the competition of B cell lineages evolving under selection for improved antigen recognition, a process known as affinity maturation…”
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Mortality Rates after Tuberculosis Treatment, Georgia, USA, 2008-2019
Published in Emerging infectious diseases (01-11-2024)“…Limited data exist on mortality rates after tuberculosis (TB) treatment in the United States. We analyzed mortality rates for all adults in Georgia, USA, who…”
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Coastal urbanization leads to remarkable seaweed species loss and community shifts along the SW Atlantic
Published in Marine pollution bulletin (15-11-2013)“…•Large declines of calcareous algal cover were observed in urban areas.•Carbonate in the sediment was significantly lower in urban areas.•Seaweed richness…”
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Yellow fever epizootics in non-human primates, Southeast and Northeast Brazil (2017 and 2018)
Published in Parasites & vectors (19-02-2020)“…Yellow fever (YF) is a severe, infectious, but non-communicable arboviral hemorrhagic disease. In the last decades, yellow fever virus (YFV) infections have…”
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IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
Published in Nature communications (04-04-2017)“…Patients who survive sepsis can develop long-term immune dysfunction, with expansion of the regulatory T (Treg) cell population. However, how Treg cells…”
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The evolutionary origins of Lévy walk foraging
Published in PLoS computational biology (01-10-2017)“…We study through a reaction-diffusion algorithm the influence of landscape diversity on the efficiency of search dynamics. Remarkably, the identical optimal…”
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The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis
Published in Journal of endocrinology (01-06-2010)“…The widespread increase in life expectancy is accompanied by an increased prevalence of features of physical frailty. Signs and symptoms may include sarcopenia…”
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Selection and Neutral Mutations Drive Pervasive Mutability Losses in Long-Lived Anti-HIV B-Cell Lineages
Published in Molecular biology and evolution (01-05-2018)“…High-affinity antibodies arise within weeks of infection from the evolution of B-cell receptors under selection to improve antigen recognition. This rapid…”
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