Search Results - "Marcondes, Marcelo F."
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Characterization of BKC-1 class A carbapenemase from Klebsiella pneumoniae clinical isolates in Brazil
Published in Antimicrobial agents and chemotherapy (01-09-2015)“…Three Klebsiella pneumoniae clinical isolates demonstrating carbapenem resistance were recovered from different patients hospitalized at two medical centers in…”
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Probing the Conformational States of Thimet Oligopeptidase in Solution
Published in International journal of molecular sciences (01-07-2022)“…Thimet oligopeptidase (TOP) is a metallopeptidase involved in the metabolism of oligopeptides inside and outside cells of various tissues. It has been proposed…”
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Reply to "Mobilization of blaBKC-1 by ISKpn23?"
Published in Antimicrobial agents and chemotherapy (01-08-2016)Get full text
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4
Intermediate Tyrosyl Radical and Amyloid Structure in Peroxide-Activated Cytoglobin
Published in PloS one (27-08-2015)“…We characterized the peroxidase mechanism of recombinant rat brain cytoglobin (Cygb) challenged by hydrogen peroxide, tert-butylhydroperoxide and by cumene…”
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Recycling of the high valence States of heme proteins by cysteine residues of THIMET-oligopeptidase
Published in PloS one (01-11-2013)“…The peptidolytic enzyme THIMET-oligopeptidase (TOP) is able to act as a reducing agent in the peroxidase cycle of myoglobin (Mb) and horseradish peroxidase…”
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Development of Chemically Defined Media to Express Trp-Analog-Labeled Proteins in a Lactococcus lactis Trp Auxotroph
Published in Journal of molecular microbiology and biotechnology (01-01-2016)“…Chemically defined media for growth of Lactococcus lactis strains contain about 50 components, making them laborious and expensive growth media. However, they…”
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Hysteretic behavior of proprotein convertase 1/3 (PC1/3)
Published in PloS one (15-09-2011)“…The proprotein convertases (PCs) are calcium-dependent proteases responsible for processing precursor proteins into their active forms in eukariotes. The PC1/3…”
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Genetic and biochemical characterization of BIM-1, a novel acquired subgroup B1 MBL found in a Pseudomonas sp. strain from the Brazilian Amazon region
Published in Journal of antimicrobial chemotherapy (01-06-2023)“…Abstract Objectives To characterize a novel acquired MBL, BIM-1, in a Pseudomonas #2 (subgroup P. guariconensis) strain isolated from the Aurá river located in…”
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Processing of metacaspase 2 from Trypanosoma brucei (TbMCA2) broadens its substrate specificity
Published in Biochimica et biophysica acta. Proteins and proteomics (01-04-2017)“…Metacaspases are members of the cysteine peptidase family and may be implicated in programmed cell death in plants and lower eukaryotes. These proteases…”
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On the efficient bio-incorporation of 5-hydroxy-tryptophan in recombinant proteins expressed in Escherichia coli with T7 RNA polymerase-based vectors
Published in Biochemical and biophysical research communications (21-10-2017)“…Biosynthetic incorporation of non-canonic amino acids is an attractive strategy to introduce new properties in recombinant proteins. Trp analogs can be…”
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CPP-Ala-Ala-Tyr-PABA inhibitor analogs with improved selectivity for neurolysin or thimet oligopeptidase
Published in Biochemical and biophysical research communications (05-02-2020)“…Thimet oligopeptidase (TOP, EC 3.4.24.15) and neurolysin (NEL, EC 3.4.24.16) are closely related zinc-dependent metalo-oligopeptidases, which take part in the…”
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Genetic and biochemical characterization of GES-16, a new GES-type β-lactamase with carbapenemase activity in Serratia marcescens
Published in Diagnostic microbiology and infectious disease (01-10-2018)“…We evaluated the genetic environment of blaGES-16 found in 2 carbapenem-resistant Serratia marcescens clinical isolates recovered from patients hospitalized at…”
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Enzymatic diversity of filamentous fungi isolated from forest soil incremented by sugar cane solid waste
Published in Environmental technology (06-09-2022)“…Fungi are natural degraders of organic matter which can produce enzymes for many industrial and biotechnological applications. In this context, crude enzymatic…”
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Substrate specificity and the effect of calcium on Trypanosoma brucei metacaspase 2
Published in The FEBS journal (01-06-2013)“…Metacaspases are cysteine peptidases found only in yeast, plants and lower eukaryotes, including the protozoa. To investigate the extended substrate…”
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Characterization of angiotensin I-converting enzyme from anterior gills of the mangrove crab Ucides cordatus
Published in International journal of biological macromolecules (01-03-2015)“…Angiotensin I-converting enzyme (ACE) is a well-known metallopeptidase that is found in vertebrates, invertebrates and bacteria. We isolated from the anterior…”
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Mitochondrial intermediate peptidase: Expression in Escherichia coli and improvement of its enzymatic activity detection with FRET substrates
Published in Biochemical and biophysical research communications (01-01-2010)“…In the present study, soluble, functionally-active, recombinant human mitochondrial intermediate peptidase (hMIP), a mitochondrial metalloendoprotease, was…”
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Catalytic properties of thimet oligopeptidase H600A mutant
Published in Biochemical and biophysical research communications (02-04-2010)“…Thimet oligopeptidase (EC 3.4.24.15, TOP) is a metallo-oligopeptidase that participates in the intracellular metabolism of peptides. Predictions based on…”
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Kinetic characterization of the Escherichia coli oligopeptidase A (OpdA) and the role of the Tyr(607) residue
Published in Archives of biochemistry and biophysics (15-08-2010)“…Oligopeptidase A (OpdA) belongs to the M3A subfamily of bacterial peptidases with catalytic and structural properties similar to mammalian…”
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Studying Prolyl Oligopeptidase Conformational Changes with Fluorescent Pyrene Probes
Published in Biophysical journal (07-02-2020)Get full text
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Reply to “Mobilization of bla BKC-1 by IS Kpn23 ?”
Published in Antimicrobial agents and chemotherapy (01-08-2016)Get full text
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