Search Results - "Marco Neves"

Docking and scoring with ICM: the benchmarking results and strategies for improvement by Neves, Marco A. C., Totrov, Maxim, Abagyan, Ruben

“…Flexible docking and scoring using the internal coordinate mechanics software (ICM) was benchmarked for ligand binding mode prediction against the 85…”
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Unusual Arginine Formations in Protein Function and Assembly: Rings, Strings, and Stacks by Neves, Marco A. C, Yeager, Mark, Abagyan, Ruben

“…Protein–protein interfaces are often stabilized by a small number of dominant contacts, exemplified by the overrepresentation of arginine residues at…”
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Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity by Sun, Ning, Chan, Fung-Yi, Lu, Yu-Jing, Neves, Marco A C, Lui, Hok-Kiu, Wang, Yong, Chow, Ka-Yan, Chan, Kin-Fai, Yan, Siu-Cheong, Leung, Yun-Chung, Abagyan, Ruben, Chan, Tak-Hang, Wong, Kwok-Yin

“…Inhibition of the functional activity of Filamenting temperature-sensitive mutant Z (FtsZ) protein, an essential and highly conserved bacterial cytokinesis…”
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Anticancer steroids: linking natural and semi-synthetic compounds by Salvador, Jorge A R, Carvalho, João F S, Neves, Marco A C, Silvestre, Samuel M, Leitão, Alcino J, Silva, M Manuel C, Sá e Melo, M Luisa

“…Steroids, a widespread class of natural organic compounds occurring in animals, plants and fungi, have shown great therapeutic value for a broad array of…”
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Antifragile Tactics for Translators—A Primer by Neves, Marco

“…Translation agents, in their professional lives, face a reality characterised by uncertainty. This uncertainty is rooted in the complexity of translation…”
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Identification of a New Class of FtsZ Inhibitors by Structure-Based Design and in Vitro Screening by Chan, Fung-Yi, Sun, Ning, Neves, Marco A. C, Lam, Polo Chun-Hung, Chung, Wai-Hong, Wong, Lai-King, Chow, Ho-Yin, Ma, Dik-Lung, Chan, Pak-Ho, Leung, Yun-Chung, Chan, Tak-Hang, Abagyan, Ruben, Wong, Kwok-Yin

“…The Filamenting temperature-sensitive mutant Z (FtsZ), an essential GTPase in bacterial cell division, is highly conserved among Gram-positive and…”
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Epstein–Barr virus strains and variations: Geographic or disease‐specific variants? by Neves, Marco, Marinho‐Dias, Joana, Ribeiro, Joana, Sousa, Hugo

“…The Epstein–Barr Virus (EBV) is associated with the development of several diseases, including infectious mononucleosis (IM), Burkitt's Lymphoma (BL),…”
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Dynamics-Based Discovery of Allosteric Inhibitors: Selection of New Ligands for the C-terminal Domain of Hsp90 by Morra, Giulia, Neves, Marco A. C, Plescia, Christopher J, Tsustsumi, Shinji, Neckers, Len, Verkhivker, Gennady, Altieri, Dario C, Colombo, Giorgio

“…The study of allosteric functional modulation in dynamic proteins is attracting increasing attention. In particular, the discovery of new allosteric sites may…”
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Smoking induces increased apoptosis in osteoblasts: changes in bone matrix organic components by Kohler, Júlia Benini, da Silva, Alex Ferreira, Farias, Walleson Alves, Sampaio, Barbara Fialho Carvalho, Neves, Marco Aurélio Silveiro, Lima, Leandro Gregorut, Lourenço, Juliana Dias, Moreira, Alyne Riani, Barbosa, Alexandre Póvoa, de Fátima Lopes Calvo Tibério, Iolanda, Teodoro, Walcy Rosolia, dos Santos Lopes, Fernanda Degobbi Tenorio Quirino

“…Clinical studies demonstrate the impact of smoking on bone tissue fragility and higher incidence of fractures. However, it is not totally understood which…”
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Time to death from cervical cancer and its predictors in hospitalized patients: a survival approach study in Mato Grosso, Brazil by Xavier, Sancho Pedro, da Silva, Kátia Moreira, Galvão, Noemi Dreyer, das Neves, Marco Aurélio Bertúlio, de Queiroz Neves Almeida, Adila, Mario Cândido da Silva, Ageo

“…Cervical cancer (CC) is a serious public health concern, being the fourth most common cancer among women and a leading cause of cancer mortality. In Brazil,…”
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Fast Three Dimensional Pharmacophore Virtual Screening of New Potent Non-Steroid Aromatase Inhibitors by Neves, Marco A. C, Dinis, Teresa C. P, Colombo, Giorgio, Sá e Melo, M. Luisa

“…Suppression of estrogen biosynthesis by aromatase inhibition is an effective approach for the treatment of hormone sensitive breast cancer. Third generation…”
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Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach by Neves, Marco A. C., Simões, Sérgio, Sá e Melo, M. Luisa

“…CXCR4 is a G-protein coupled receptor for CXCL12 that plays an important role in human immunodeficiency virus infection, cancer growth and metastasization,…”
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An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors by Neves, Marco A.C., Dinis, Teresa C.P., Colombo, Giorgio, Sá e Melo, M. Luisa

“…Aromatase, an enzyme involved in the conversion of androgens into estrogens, is an important target for the endocrine treatment of breast cancer. Aromatase…”
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Collagen changes and realignment induced by low-level laser therapy and low-intensity ultrasound in the calcaneal tendon by Wood, Viviane T., Pinfildi, Carlos E., Neves, Marco A.I., Parizoto, Nivaldo A., Hochman, Bernardo, Ferreira, Lydia M.

“…Background and Objective The treatment of calcaneal tendon injuries requires long‐term rehabilitation. Ultrasound (US) and low‐level laser therapy (LLLT) are…”
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What is better in TRAM flap survival: LLLT single or multi-irradiation? by Pinfildi, Carlos Eduardo, Hochman, Bernardo S., Nishioka, Michele Akemi, Sheliga, Tatiana Rodrigues, Neves, Marco Aurélio Invaldi, Liebano, Richard Eloin, Ferreira, Lydia Masako

“…Low-level laser therapy (LLLT) has been used with the aim of improving vascular perfusion of the skin and musculocutaneous flaps. This study evaluated the…”
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A new microtubule-stabilizing agent shows potent antiviral effects against African swine fever virus with no cytotoxicity by Sirakanyan, Samvel, Arabyan, Erik, Hakobyan, Astghik, Hakobyan, Tamara, Chilingaryan, Garri, Sahakyan, Harutyun, Sargsyan, Arsen, Arakelov, Grigor, Nazaryan, Karen, Izmailyan, Roza, Abroyan, Liana, Karalyan, Zaven, Arakelova, Elina, Hakobyan, Elmira, Hovakimyan, Anush, Serobian, Andre, Neves, Marco, Ferreira, João, Ferreira, Fernando, Zakaryan, Hovakim

“…African swine fever virus (ASFV) is the causal agent of a fatal disease of domestic swine for which no effective antiviral drugs are available. Recently, it…”
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Cancer mortality in the State of Mato Grosso from 2000 to 2015: temporal trend and regional differences by Modesto, Viviane Cardozo, Evangelista, Flávio de Macêdo, Soares, Mariana Rosa, Alves, Mário Ribeiro, Neves, Marco Aurélio Bertúlio das, Corrêa, Marcia Leopoldina Montanari, Sousa, Neuciani Ferreira da Silva E, Galvão, Noemi Dreyer, Andrade, Amanda Cristina de Souza

“…To analyze the trend of standardized cancer mortality rate in the state of Mato Grosso according to health regions, from 2000 to 2015. Ecological time series…”
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Incidence, mortality and survival of prostate cancer in two municipalities with a high human development index in Mato Grosso, Brazil by Evangelista, Flávio de Macêdo, Melanda, Francine Nesello, Modesto, Viviane Cardozo, Soares, Mariana Rosa, Neves, Marco Aurélio Bertúlio das, Souza, Bárbara da Silva Nalin de, Sousa, Neuciani Ferreira da Silva e, Galvão, Noemi Dreyer, Andrade, Amanda Cristina de Souza

“…Objective: To analyze the incidence, mortality and survival of prostate cancer in Cuiabá and Várzea Grande, Brazil from 2000 to 2016. Methods: Data from the…”
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Validation of the AmpC β-Lactamase Binding Site and Identification of Inhibitors with Novel Scaffolds by Chan, Fung-Yi, Neves, Marco A. C., Sun, Ning, Tsang, Man-Wah, Leung, Yun-Chung, Chan, Tak-Hang, Abagyan, Ruben, Wong, Kwok-Yin

“…AmpC β-lactamase confers resistance to β-lactam antibiotics in multiple Gram-negative bacteria. Therefore, identification of non-β-lactam compounds that…”
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Low Sensitivity of the Mini-Mental State Examination for Cognitive Assessment of Brazilian Patients With Parkinson Disease by Breder, Raphael, Leite, Marco Antonio Araujo, Pinto, Jony Arrais, Cavalcante, Igor Pinto, Pessoa, Bruno Lima, Neves, Marco Antônio Orsini

“…Introduction: Recent publications have highlighted the low sensitivity of the Mini-Mental State Examination (MMSE) for the cognitive assessment of patients…”
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