Search Results - "Marcinkiewicz, Mariola"

A Novel Approach for Ovine Primary Alveolar Epithelial Type II Cell Isolation and Culture from Fresh and Cryopreserved Tissue Obtained from Premature and Juvenile Animals by Marcinkiewicz, Mariola M, Baker, Sandy T, Wu, Jichuan, Hubert, Terrence L, Wolfson, Marla R

“…The in vivo ovine model provides a clinically relevant platform to study cardiopulmonary mechanisms and treatments of disease; however, a robust ovine primary…”
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Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation by Trujillo, Marissa N., Jennings, Erin Q., Hoffman, Emely A., Zhang, Hao, Phoebe, Aiden M., Mastin, Grace E., Kitamura, Naoya, Reisz, Julie A., Megill, Emily, Kantner, Daniel, Marcinkiewicz, Mariola M., Twardy, Shannon M., Lebario, Felicidad, Chapman, Eli, McCullough, Rebecca L., D'Alessandro, Angelo, Snyder, Nathaniel W., Cusanovich, Darren A., Galligan, James J.

“…Chronic, systemic inflammation is a pathophysiological manifestation of metabolic disorders. Inflammatory signaling leads to elevated glycolytic flux and a…”
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Productive Recognition of Factor IX by Factor XIa Exosites Requires Disulfide Linkage between Heavy and Light Chains of Factor XIa by Marcinkiewicz, Mariola M., Sinha, Dipali, Walsh, Peter N.

“…In the intrinsic pathway of blood coagulation factor XIa (FXIa) activates factor IX (FIX) by cleaving the zymogen at Arg145-Ala146 and Arg180-Val181 bonds…”
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A Subpopulation of Platelets Responds to Thrombin- or SFLLRN-stimulation with Binding Sites for Factor IXa by London, Fredda S, Marcinkiewicz, Mariola, Walsh, Peter N

“…Strong agonists cause platelets to expose a procoagulant surface supporting the assembly of two important coagulation enzyme complexes. Equilibrium binding has…”
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Macromolecular Substrate-Binding Exosites on Both the Heavy and Light Chains of Factor XIa Mediate the Formation of the Michaelis Complex Required for Factor IX-Activation by Sinha, Dipali, Marcinkiewicz, Mariola, Navaneetham, Duraiswamy, Walsh, Peter N

“…Binding of factor IX (FIX) to an exosite on the heavy chain of factor XIa (FXIa) is essential for the optimal activation of FIX (Sinha, D., Seaman, F. S., and…”
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PAR-1-Stimulated Factor IXa Binding to a Small Platelet Subpopulation Requires a Pronounced and Sustained Increase of Cytoplasmic Calcium by London, Fredda S, Marcinkiewicz, Mariola, Walsh, Peter N

“…We previously reported that only a subpopulation of PAR-1-stimulated platelets binds coagulation factor IXa, since confirmed by other laboratories. Since…”
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Isolation and Characterization of EMS16, a C-Lectin Type Protein from Echis multisquamatus Venom, a Potent and Selective Inhibitor of the α2β1 Integrin by Marcinkiewicz, Cezary, Lobb, Roy R, Marcinkiewicz, Mariola M, Daniel, James L, Smith, J. Bryan, Dangelmaier, Carol, Weinreb, Paul H, Beacham, Dorothy A, Niewiarowski, Stefan

“…We have isolated and characterized EMS16, a potent and selective inhibitor of the α2β1 integrin, from Echis multisquamatus venom. It belongs to the family of…”
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Structural and Functional Characterization of EMF10, a Heterodimeric Disintegrin from Eristocophis macmahoni Venom That Selectively Inhibits α5β1 Integrin by Marcinkiewicz, Cezary, Calvete, Juan J, Vijay-Kumar, Senadhi, Marcinkiewicz, Mariola M, Raida, Manfred, Schick, Paul, Lobb, Roy R, Niewiarowski, Stefan

“…α5β1, a major fibronectin receptor, is a widely distributed integrin that is essential for cell growth and organ development. Here, we describe a novel…”
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A Novel Ovine Primary Alveolar Type II Cell Culture Approach by Marcinkiewicz, Mariola, Allen, Natalie, Hubert, Terrence, Wolfson, Marla

“…Abstract only…”
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Utility of Abbreviated Exposure Time in Mice ‐ Contribution to Understanding Pathogenesis of Cigarette Smoke Induced Lung Disease by Wolfson, Marla R, Baker, Sandy T, Tian, Ying, Bahmed, Karim, Kosmider, Beata, Marcinkiewicz, Mariola M, Wu, Jichuan

“…Abstract only…”
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A Novel Approach for Ovine Primary Alveolar Epithelial Type II Cell Isolation and Culture from Fresh and Cryopreserved Tissue Obtained from Premature and Juvenile Animals: e0152027 by Marcinkiewicz, Mariola M, Baker, Sandy T, Wu, Jichuan, Hubert, Terrence L, Wolfson, Marla R

“…The in vivo ovine model provides a clinically relevant platform to study cardiopulmonary mechanisms and treatments of disease; however, a robust ovine primary…”
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EC3, a Novel Heterodimeric Disintegrin from Echis carinatus Venom, Inhibits α4 and α5 Integrins in an RGD-independent Manner by Marcinkiewicz, Cezary, Calvete, Juan J., Marcinkiewicz, Mariola M., Raida, Manfred, Vijay-Kumar, Senadhi, Huang, Ziwei, Lobb, Roy R., Niewiarowski, Stefan

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Inhibitory Effects of MLDG-containing Heterodimeric Disintegrins Reveal Distinct Structural Requirements for Interaction of the Integrin α9β1 with VCAM-1, Tenascin-C, and Osteopontin by Marcinkiewicz, Cesary, Taooka, Yasuyuki, Yokosaki, Yasuyuki, Calvete, Juan J., Marcinkiewicz, Mariola M., Lobb, Roy R., Niewiarowski, Stefan, Sheppard, Dean

“…The integrin α9β1 is expressed on epithelial cells, smooth muscle cells, skeletal muscle, and neutrophils and recognizes at least three distinct ligands:…”
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Factor IX Substrate Binding Exosite on the Light Chain of Factor Xia by Sinha, Dipali, Marcinkiewicz, Mariola, Navaneetham, Duraiswamy, Walsh, Peter N.

“…Binding of factor IX (FIX) to an exosite on the heavy chain of factor XIa (FXIa) is essential for the optimal activation of FIX (Biochemistry 26:3768–3775,…”
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Factor XIa Dimer in the Activation of Factor IX by Sinha, Dipali, Marcinkiewicz, Mariola, Lear, James D, Walsh, Peter N

“…Factor XI, unlike other coagulation proteins, is a homodimer of two identical subunits linked by a single disulfide bond formed by Cys321. The present study…”
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Selective recognition of α2β1 integrin by jararhagin, a metalloproteinase/disintegrin from Bothrops jararaca venom by MOURA-DA-SILVA, Ana M, MARCINKIEWICZ, Cezary, MARCINKIEWICZ, Mariola, NIEWIAROWSKI, Stefan

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Allosteric Modification of Factor XIa Functional Activity upon Binding to Polyanions by Sinha, Dipali, Badellino, Karen O, Marcinkiewicz, Mariola, Walsh, Peter N

“…The effects of several polyanions on the hydrolysis of the chromogenic substrate l-pyroglutamyl-l-prolyl-l-arginyl-p-nitroaniline (S-2366) and on the…”
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Molecular cloning and biochemical characterization of rabbit factor XI by Sinha, Dipali, Marcinkiewicz, Mariola, Gailani, David, Walsh, Peter N

“…Human factor XI, a plasma glycoprotein required for normal haemostasis, is a homodimer (160 kDa) formed by a single interchain disulphide bond linking the…”
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Structural Requirements of Echistatin for the Recognition of αvβ3 and α5β1Integrins by Wierzbicka-Patynowski, Iwona, Niewiarowski, Stefan, Marcinkiewicz, Cezary, Calvete, Juan J., Marcinkiewicz, Mariola M., McLane, Mary Ann

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Selective Recognition of α 2β 1 Integrin by Jararhagin, a Metalloproteinase/Disintegrin from Bothrops jararaca Venom by Moura-da-Silva, Ana M., Marcinkiewicz, Cezary, Marcinkiewicz, Mariola, Niewiarowski, Stefan

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