Search Results - "Marcin Kruszewski"

Micronucleus Assay: The State of Art, and Future Directions by Sommer, Sylwester, Buraczewska, Iwona, Kruszewski, Marcin

“…During almost 40 years of use, the micronucleus assay (MN) has become one of the most popular methods to assess genotoxicity of different chemical and physical…”
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Targeted Radionuclide Therapy of Prostate Cancer-From Basic Research to Clinical Perspectives by Czerwińska, Malwina, Bilewicz, Aleksander, Kruszewski, Marcin, Wegierek-Ciuk, Aneta, Lankoff, Anna

“…Prostate cancer is the most commonly diagnosed malignancy in men and the second leading cause of cancer-related deaths in Western civilization. Although…”
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Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis by Stępkowski, Tomasz M., Kruszewski, Marcin K.

“…Oxidative stress, perturbations in the cellular thiol level and redox balance, affects many cellular functions, including signaling pathways. This, in turn,…”
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Nanoparticle-Based Radioconjugates for Targeted Imaging and Therapy of Prostate Cancer by Lankoff, Anna, Czerwińska, Malwina, Kruszewski, Marcin

“…Prostate cancer is the second most frequent malignancy in men worldwide and the fifth leading cause of death by cancer. Although most patients initially…”
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Silver, Gold, and Iron Oxide Nanoparticles Alter miRNA Expression but Do Not Affect DNA Methylation in HepG2 Cells by Brzóska, Kamil, Grądzka, Iwona, Kruszewski, Marcin

“…The increasing use of nanoparticles (NPs) in various applications entails the need for reliable assessment of their potential toxicity for humans. Originally,…”
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Nanoplastic Impact on the Gut-Brain Axis: Current Knowledge and Future Directions by Grodzicki, Wojciech, Dziendzikowska, Katarzyna, Gromadzka-Ostrowska, Joanna, Kruszewski, Marcin

“…The widespread usage of plastic places a significant burden on the environment and impacts numerous aquatic and terrestrial species. Humans in particular can…”
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Toxicity of titanium dioxide nanoparticles in central nervous system by Czajka, Magdalena, Sawicki, Krzysztof, Sikorska, Katarzyna, Popek, Sylwia, Kruszewski, Marcin, Kapka-Skrzypczak, Lucyna

“…•TiO2 NPs can translocate from the initial gates of entry and accumulate in the brain.•TiO2 NPs accumulation in the brain causes brain damage and…”
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Differential Action of Silver Nanoparticles on ABCB1 (MDR1) and ABCC1 (MRP1) Activity in Mammalian Cell Lines by Krzyzanowski, Damian, Kruszewski, Marcin, Grzelak, Agnieszka

“…Silver nanoparticles (AgNPs), due to their unique properties have been receiving immense attention in recent years. In addition to their antibacterial and…”
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Coating-Dependent Neurotoxicity of Silver Nanoparticles-An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids by Dziendzikowska, Katarzyna, Wilczak, Jacek, Grodzicki, Wojciech, Gromadzka-Ostrowska, Joanna, Węsierska, Małgorzata, Kruszewski, Marcin

“…Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials. The level of exposure to nanosilver is constantly raising, and a growing body of…”
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The comet assay as a tool for human biomonitoring studies: The ComNet Project by Collins, Andrew, Koppen, Gudrun, Valdiglesias, Vanessa, Dusinska, Maria, Kruszewski, Marcin, Møller, Peter, Rojas, Emilio, Dhawan, Alok, Benzie, Iris, Coskun, Erdem, Moretti, Massimo, Speit, Günter, Bonassi, Stefano

“…The comet assay is widely used in human biomonitoring to measure DNA damage as a marker of exposure to genotoxic agents or to investigate genoprotective…”
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DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death by Bonassi, Stefano, Ceppi, Marcello, Møller, Peter, Azqueta, Amaya, Milić, Mirta, Neri, Monica, Brunborg, Gunnar, Godschalk, Roger, Koppen, Gudrun, Langie, Sabine A. S., Teixeira, João Paulo, Bruzzone, Marco, Da Silva, Juliana, Benedetti, Danieli, Cavallo, Delia, Ursini, Cinzia Lucia, Giovannelli, Lisa, Moretti, Silvia, Riso, Patrizia, Del Bo’, Cristian, Russo, Patrizia, Dobrzyńska, Malgorzata, Goroshinskaya, Irina A., Surikova, Ekaterina I., Staruchova, Marta, Barančokova, Magdalena, Volkovova, Katarina, Kažimirova, Alena, Smolkova, Bozena, Laffon, Blanca, Valdiglesias, Vanessa, Pastor, Susana, Marcos, Ricard, Hernández, Alba, Gajski, Goran, Spremo-Potparević, Biljana, Živković, Lada, Boutet-Robinet, Elisa, Perdry, Hervé, Lebailly, Pierre, Perez, Carlos L., Basaran, Nursen, Nemeth, Zsuzsanna, Safar, Anna, Dusinska, Maria, Collins, Andrew

“…The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human…”
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A Crucial Role of Proteolysis in the Formation of Intracellular Dinitrosyl Iron Complexes by Wójciuk, Karolina E, Sadło, Jarosław, Lewandowska, Hanna, Brzóska, Kamil, Kruszewski, Marcin

“…Dinitrosyl iron complexes (DNICs) stabilize nitric oxide in cells and tissues and constitute an important form of its storage and transportation. DNICs may…”
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The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells by Lankoff, Anna, Sandberg, Wiggo J., Wegierek-Ciuk, Aneta, Lisowska, Halina, Refsnes, Magne, Sartowska, Bożena, Schwarze, Per E., Meczynska-Wielgosz, Sylwia, Wojewodzka, Maria, Kruszewski, Marcin

“…► Ag and TiO 2 nanoparticles are efficiently taken up by A549, HepG2 and THP1 cells. ► Ag and TiO 2 nanoparticles decrease metabolic activation and increase…”
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Adverse Effects of Non-Metallic Nanoparticles in the Central Nervous System by Sikorska, Katarzyna, Sawicki, Krzysztof, Czajka, Magdalena, Kapka-Skrzypczak, Lucyna, Kruszewski, Marcin, Brzóska, Kamil

“…The interest in nanoparticles (NPs) and their effects on living organisms has been continuously growing in the last decades. A special interest is focused on…”
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Exposure to Chlorpyrifos Alters Proliferation, Differentiation and Fatty Acid Uptake in 3T3-L1 Cells by Czajka, Magdalena, Sawicki, Krzysztof, Matysiak-Kucharek, Magdalena, Kruszewski, Marcin, Kurzepa, Jacek, Wojtyła-Buciora, Paulina, Kapka-Skrzypczak, Lucyna

“…Organophosphorus pesticides (OPs) are important factors in the etiology of many diseases, including obesity and type 2 diabetes mellitus. The aim of this study…”
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Silver Nanoparticles Impair Cognitive Functions and Modify the Hippocampal Level of Neurotransmitters in a Coating-Dependent Manner by Dziendzikowska, Katarzyna, Węsierska, Małgorzata, Gromadzka-Ostrowska, Joanna, Wilczak, Jacek, Oczkowski, Michał, Męczyńska-Wielgosz, Sylwia, Kruszewski, Marcin

“…Due to their potent antibacterial properties, silver nanoparticles (AgNPs) are widely used in industry and medicine. However, they can cross the brain-blood…”
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Design and Evaluation of 223Ra-Labeled and Anti-PSMA Targeted NaA Nanozeolites for Prostate Cancer Therapy–Part I by Czerwińska, Malwina, Fracasso, Giulio, Pruszyński, Marek, Bilewicz, Aleksander, Kruszewski, Marcin, Majkowska-Pilip, Agnieszka, Lankoff, Anna

“…Prostate cancer is the second most frequent malignancy in men worldwide. Unfortunately, current therapies often lead to the onset of metastatic…”
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Quantum dots as targeted doxorubicin drug delivery nanosystems by Monika Ruzycka-Ayoush, Patrycja Kowalik, Agata Kowalczyk, Piotr Bujak, Anna M. Nowicka, Maria Wojewodzka, Marcin Kruszewski, Ireneusz P. Grudzinski

“…Abstract Background Lung cancer is one of the most frequently diagnosed cancers all over the world and is also one of the leading causes of cancer-related…”
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Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity by Grzelak, Agnieszka, Wojewódzka, Maria, Meczynska-Wielgosz, Sylwia, Zuberek, Mariusz, Wojciechowska, Dominika, Kruszewski, Marcin

“…Damage to mitochondria and subsequent ROS leakage is a commonly accepted mechanism of nanoparticle toxicity. However, malfunction of mitochondria results in…”
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In Vivo Pro-Inflammatory Effects of Silver Nanoparticles on the Colon Depend on Time and Route of Exposure by Grodzicki, Wojciech, Dziendzikowska, Katarzyna, Gromadzka-Ostrowska, Joanna, Wilczak, Jacek, Oczkowski, Michał, Kopiasz, Łukasz, Sapierzyński, Rafał, Kruszewski, Marcin, Grzelak, Agnieszka

“…Nanosilver is a popular nanomaterial, the potential influence of which on humans is of serious concern. Herein, we exposed male Wistar rats to two regimens: a…”
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