Search Results - "Marciano, Michael A."

Revisiting single cell analysis in forensic science by Watkins, Davis R. L., Myers, Dan, Xavier, Hannah E., Marciano, Michael A.

“…Forensic science has yet to take full advantage of single cell analysis. Its greatest benefit is the ability to alleviate the challenges associated with DNA…”
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Enhanced DNA mixture deconvolution of sexual offense samples using the DEPArray™ system by Williamson, Victoria R., Laris, Taylor M., Romano, Rita, Marciano, Michael A.

“…•Individual cells can be selectively recovered from heterogeneous mixtures, precluding the need for downstream mixture deconvolution.•The DEPArray™ permits…”
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A hybrid approach to increase the informedness of CE-based data using locus-specific thresholding and machine learning by Marciano, Michael A., Williamson, Victoria R., Adelman, Jonathan D.

“…•The proposed method of allele detection and artifact removal combines a dynamic analytical threshold with machine learning to increase the rate of correct…”
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Enhancing research and collaboration in forensic science: A primer on data sharing by Marciano, Michael A., Maynard, Henry P.

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Enhancing research and collaboration in forensic science: A primer on human subjects’ research protection by Marciano, Michael A., Hall, Ashley, Mozayani, Ashraf, Cromp, Tracy, Maynard, Henry P.

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A systematic approach to improve downstream single-cell analysis for the DEPArray™ technology by Schulte, Janine, Marciano, Michael A, Scheurer, Eva, Schulz, Iris

“…Most commercially available STR amplification kits have never been fully validated for low template DNA analysis, highlighting the need for testing different…”
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PACE: Probabilistic Assessment for Contributor Estimation- a machine learning-based assessment of the number of contributors in DNA mixtures by Marciano, Michael A, Adelman, Jonathan D

“…Highlights • The introduction of a new and powerful technique to estimate the number of contributors in a DNA mixture and convey the results probabilistically…”
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Developmental validation of PACE™: Automated artifact identification and contributor estimation for use with GlobalFiler™ and PowerPlex® fusion 6c generated data by Marciano, Michael A, Adelman, Jonathan D

“…Highlights•PACE can be used with GlobalFiler & PowerPlex Fusion 6c generated samples. •Automated artifact identification and removal is >93.5% accurate…”
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Targeted recovery of male cells in a male and female same‐cell mixture by Hogg, Jonathan, Vandepoele, Amber C. W., Zaccheo, Nori, Schulte, Janine, Schulz, Iris, Dubois, Jeremy, Frank, Morgan, Marciano, Michael A.

“…DNA mixture deconvolution in the forensic DNA community has been addressed in a variety of ways. “Front‐end” methods that separate the cellular components of…”
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Development of a Method to Extract Opium Poppy (Papaver somniferum L.) DNA from Heroin by Marciano, Michael A., Panicker, Sini X., Liddil, Garrett D., Lindgren, Danielle, Sweder, Kevin S.

“…This study is the first to report the successful development of a method to extract opium poppy ( Papaver somniferum L .) DNA from heroin samples. Determining…”
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Racial/ethnic discrimination, ADH1B3, and coping‐motivated drinking among Black college students by Zaso, Michelle J., Kim, Jueun, Desalu, Jessica M., Goodhines, Patricia A., Marciano, Michael A., Park, Aesoon

“…Background and Objectives Discrimination due to race and/or ethnicity can be a pervasive stressor for Black college students in the United States beyond…”
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Automated detection and removal of capillary electrophoresis artifacts due to spectral overlap by Adelman, Jonathan D., Zhao, Angie, Eberst, D. Spencer, Marciano, Michael A.

“…While DNA detection using capillary electrophoresis has enabled improvements in both resolution and throughput, the use of CE – particularly with multiple dye…”
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Interaction Effects between the Cumulative Genetic Score and Psychosocial Stressor on Self-Reported Drinking Urge and Implicit Attentional Bias for Alcohol: A Human Laboratory Study by Kim, Jueun, Marciano, Michael A, Ninham, Shyanne, Zaso, Michelle J, Park, Aesoon

“…Individuals with high cumulative genetic risk score of the five monoamergic genotypes showed greater attentional bias toward alcohol cues when exposed to a…”
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Assessing non-LUS stutter in DNA sequence data by D’Angelo, Olivia, Vandepoele, Amber C.W., Adelman, Jonathan, Marciano, Michael A.

“…Forensic DNA analysis is among the most well-recognized and well-developed forensic disciplines. The field’s use of DNA markers known as short tandem repeats…”
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Interpretation Methods for Complex and Low Quality DNA Profiles by Marciano, Michael A

“…DNA has long been the “gold-standard” for the identification of organisms. It plays a central role in revealing the past by answering the questions who, what,…”
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