Search Results - "Marchuk, L"

Matrix Metalloproteinase and Tissue Inhibitor of Matrix Metalloproteinase mRNA Levels Are Specifically Altered in Torn Rotator Cuff Tendons by Lo, Ian K. Y., Marchuk, Linda L., Hollinshead, Robert, Hart, David A., Frank, Cyril B.

“…Background : Rotator cuff tears are a cause of pain and disability in the shoulder. The molecular changes associated with rotator cuff tearing are unclear. A…”
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INSTITUTIONAL ASPECTS OF THE REGULATION OF ECONOMIC SECURITY OF THE AGRICULTURAL PRODUCTION by I., Gryshova, O., Nikoliuk, L., Marchuk

“…The article considers the regulation of economic security of the agricultural production as a complexintegrated element of the general system of innovative…”
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Technical issues in using robots to reproduce joint specific gait by Rosvold, J M, Darcy, S P, Peterson, R C, Achari, Y, Corr, D T, Marchuk, L L, Frank, C B, Shrive, N G, Rosvold, Joshua M, Darcy, Shon P, Peterson, Robert C, Achari, Yamini, Corr, David T, Marchuk, Linda L, Frank, Cyril B, Shrive, Nigel G

“…Reproduction of the in vivo motions of joints has become possible with improvements in robot technology and in vivo measuring techniques. A motion analysis…”
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Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues by Reno, C, Marchuk, L, Sciore, P, Frank, C B, Hart, D A

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Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo by Nakamura, N, Hart, D A, Boorman, R S, Kaneda, Y, Shrive, N G, Marchuk, L L, Shino, K, Ochi, T, Frank, C B

“…Injured ligaments heal with scar tissue, which has mechanical properties inferior to those of normal ligament, potentially resulting in re-injury, joint…”
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Comparison of mRNA levels for matrix molecules in normal and disrupted human anterior cruciate ligaments using reverse transcription-polymerase chain reaction by Lo, I K, Marchuk, L L, Hart, D A, Frank, C B

“…Midsubstance samples of anterior cruciate ligaments from seven normal human cadaver knees (16-50 years old) were harvested and compared with midsubstance…”
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Strength of medial structures of the knee joint are decreased by isolated injury to the medial collateral ligament and subsequent joint immobilization by Thornton, G.M., Johnson, J.C., Maser, R.V., Marchuk, L.L., Shrive, N.G., Frank, C.B.

“…Past studies of the healing of the medial collateral ligament (MCL) in animal models have been conducted over a variety of healing intervals, some as early as…”
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Compressive compared with tensile loading of medial collateral ligament scar in vitro uniquely influences mRNA levels for aggrecan, collagen type II, and collagenase by Majima, T, Marchuk, L L, Sciore, P, Shrive, N G, Frank, C B, Hart, D A

“…To test the hypothesis that loading conditions can be used to engineer early ligament scar behaviors, we used an in vitro system to examine the effect that…”
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Postmortem stability of total RNA isolated from rabbit ligament, tendon and cartilage by Marchuk, L, Sciore, P, Reno, C, Frank, C.B, Hart, D.A

“…The stability of RNA, particularly mRNA, in tissues is under complex regulation. Most studies to date have focused on very cellular tissues and not connective…”
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Efficient Transfer of Intact Oligonucleotides into the Nucleus of Ligament Scar Fibroblasts by HVJ-Cationic Liposomes Is Correlated with Effective Antisense Gene Inhibition by Nakamura, Norimasa, Hart, David A., Frank, Cyril B., Marchuk, Linda L., Shrive, Nigel G., Ota, Naruhisa, Taira, Kazunari, Yoshikawa, Hideki, Kaneda, Yasufumi

“…The efficacy of two different cationic liposomes, Lipofectin and hemagglutinating virus of Japan (HVJ)-cationic liposomes, on nuclear uptake of…”
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Effects of ligament repair on laxity and creep behavior of an early healing ligament scar by Majima, Tokifumi, Lo, Ian K Y, Marchuk, Linda L, Shrive, Nigel G, Frank, Cyril B

“…Previous clinical studies have reported that conservatively managed medial collateral ligament (MCL) injuries remained unstable 9 years post injury with…”
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Asynchronous Muscle and Tendon Adaptation After Surgical Tensioning Procedures by Takahashi, Mitsuhiko, Ward, Samuel R, Marchuk, Linda L, Frank, Cyril B, Lieber, Richard L

“…BACKGROUND:Donor muscles are often highly stretched in tendon transfer surgery. Despite literature reports that showed adaptation of the serial sarcomere…”
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Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament by Chimich, D, Shrive, N, Frank, C, Marchuk, L, Bray, R

“…Testing environment is an important factor in the outcome of mechanical tests on connective tissue. The purpose of this investigation was to determine the…”
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In-vitro cyclic tensile loading of an immobilized and mobilized ligament autograft selectively inhibits mRNA levels for collagenase (MMP-1) by Majima, T, Marchuk, L L, Shrive, N G, Frank, C B, Hart, D A

“…To test the hypothesis that loading conditions can be used to "engineer" ligament autograft behaviors, the effect of cyclic tension on the mRNA levels of…”
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The cellular networks of normal ovine medial collateral and anterior cruciate ligaments are not accurately recapitulated in scar tissue by Lo, Ian K. Y., Ou, Yong, Rattner, John‐Paul, Hart, David A., Marchuk, Linda L., Frank, Cyril B., Rattner, Jerome B.

“…The purpose of this study was to characterize the cellular organization of the ovine medial collateral ligament (MCL) and anterior cruciate ligament (ACL) and…”
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Collagen fibrillogenesis and mRNA levels in the maturing rabbit medial collateral ligament and patellar tendon by Lo, Ian K Y, Marchuk, Linda L, Leatherbarrow, Kate E, Frank, Cyril B, Hart, David A

“…This study compared collagen fibril diameter and mRNA changes in a subset of molecules involved in collagen fibrillogenesis during postnatal development and at…”
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ACL transection influences mRNA levels for collagen type I and TNF-α in MCL scar by Majima, Tokifumi, Lo, Ian K.Y, Randle, John A, Marchuk, Linda L, Shrive, Nigel G, Frank, Cyril B, Hart, David A

“…To assess the mRNA expression of extracellular matrix genes which might correlate with or contribute to mechanically weaker medial collateral ligament (MCL)…”
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Soft-tissue "flaws" are associated with the material properties of the healing rabbit medial collateral ligament by Shrive, N, Chimich, D, Marchuk, L, Wilson, J, Brant, R, Frank, C

“…This study evaluated microscopic flaws in the healing rabbit medial collateral ligament and their significance in terms of the material properties of this…”
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Summary and Future Directions by Frank, Cyril B, Marchuk, Linda L, Woo, Savio L-Y

“…Ligaments are highly organized loose connective tissues that look simple, but they are not. They have very complex structures, functions, and biology making…”
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Complexity of determining cause and effect in vivo after antisense gene therapy by Hart, D A, Nakamura, N, Marchuk, L, Hiraoka, H, Boorman, R, Kaneda, Y, Shrive, N G, Frank, C B

“…Injuries to joint tissues are major clinical problems occurring with significant frequency and resulting in the formation of scar tissue or in some tissues…”
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