Search Results - "Marchisio, PC"
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Release of eIF6 (p27 BBP ) from the 60S subunit allows 80S ribosome assembly
Published in Nature (04-12-2003)“…The assembly of 80S ribosomes requires joining of the 40S and 60S subunits, which is triggered by the formation of an initiation complex on the 40S subunit…”
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2
Regulation of Survivin Function by Hsp90
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2003)“…Pathways controlling cell proliferation and cell survival require flexible adaptation to environmental stresses. These mechanisms are frequently exploited in…”
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3
Control of apoptosis and mitotic spindle checkpoint by survivin
Published in Nature (London) (10-12-1998)“…Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes, acting to preserve homeostasis…”
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4
Regulation of microtubule stability and mitotic progression by survivin
Published in Cancer research (Chicago, Ill.) (01-05-2002)“…Survivin is a member of the inhibitor of apoptosis (IAP) gene family, which has been implicated in both preservation of cell viability and regulation of…”
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5
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
Published in Nature cell biology (01-12-1999)“…Here we investigate the role of the control of apoptosis in normal cell division. We show that interference with the expression or function of the apoptosis…”
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6
Podosomes as smart regulators of cellular adhesion
Published in European journal of cell biology (01-04-2006)“…Podosomes are punctate adhesion structures first described in osteoclasts and next found in src-transformed cells of mesenchymal origin. Podosomes were never…”
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7
Role of Bone Marrow Stromal Cells in the Growth of Human Multiple Myeloma
Published in Blood (15-06-1991)“…We have verified the hypothesis that multiple myeloma (MM) may be disseminated by circulating clonogenic cells that selectively home to the bone marrow (BM) to…”
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8
Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function
Published in Journal of cell science (01-02-2002)“…Survivin is a member of the inhibitor of apoptosis gene family that has been implicated in both apoptosis inhibition and regulation of mitosis. However, the…”
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9
A dynamic podosome-like structure of epithelial cells
Published in Experimental cell research (01-05-2004)“…Focal contacts and hemidesmosomes are cell–matrix adhesion structures of cultured epithelial cells. While focal contacts link the extracellular matrix to…”
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10
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing
Published in The Journal of cell biology (01-05-1995)“…The molecular mechanism underlying the promotion of wound healing by TGF-beta 1 is incompletely understood. We report that TGF-beta 1 regulates the…”
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11
Fibronectin controls cap-dependent translation through beta 1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2005)“…Fibronectin (FN) is a major matrix protein involved in multiple processes. Little is known about how adhesion to FN affects the translational machinery. We…”
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Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport
Published in The Journal of clinical investigation (15-06-1996)“…The adducin heterodimer is a protein affecting the assembly of the actin-based cytoskeleton. Point mutations in rat adducin alpha (F316Y) and beta (Q529R)…”
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13
VE-Cadherin Expression and Clustering Maintain Low Levels of Survivin in Endothelial Cells
Published in The American journal of pathology (01-07-2004)“…Survivin is strongly expressed in embryonic organs and in tumor cells but is low or absent in differentiated normal tissues. Resting endothelium expresses low…”
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14
Sen34p depletion blocks tRNA splicing in vivo and delays rRNA processing
Published in Biochemical and biophysical research communications (11-11-2005)“…Tif6p (eIF6) is necessary for 60S biogenesis, rRNA maturation and must be released from 60S to permit 80S assembly and translation. We characterized Tif6p…”
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15
The alpha 3 beta 1 integrin is involved in melanoma cell migration and invasion
Published in Experimental cell research (01-07-1995)“…The VLA3 (alpha 3 beta 1) integrin receptor recognizes several ligands; however, the function of this integrin is still debated. Expression of VLA3 appears to…”
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The Role of Integrins in the Maintenance of Endothelial Monolayer Integrity
Published in The Journal of cell biology (01-02-1991)“…This paper shows that, in confluent human umbilical vein endothelial cell (EC) monolayers, the integrin heterodimers α 2β 1 and α 5β 1, but not other members…”
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17
Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loop
Published in The Journal of biological chemistry (25-10-1993)“…Normal human keratinocytes synthesize and secrete biologically active nerve growth factor (NGF) in a growth regulated fashion (Di Marco, E., Marchisio, P. C.,…”
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Polarized Expression of Integrin Receptors (α 6β 4,α 2β 1,α 3β 1, and α vβ 5) and Their Relationship with the Cytoskeleton and Basement Membrane Matrix in Cultured Human Keratinocytes
Published in The Journal of cell biology (01-02-1991)“…In human keratinocytes cultured in conditions which allow differentiation and stratification and are suitable to reconstitute a fully functional epidermis, α…”
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Formation of nuclear matrix filaments by p27BBP/eIF6
Published in Biochemical and biophysical research communications (12-07-2002)Get full text
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20
Changes in Integrin and E-Cadherin Expression in Neoplastic Versus Normal Thyroid Tissue
Published in JNCI : Journal of the National Cancer Institute (03-04-1996)“…Background The functional organization of polarized epithelia depends mostly on adhesion molecules belonging to the integrin and cadherin families. These…”
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