Search Results - "Marchfelder, A"

tRNase Z: the end is not in sight by Späth, B, Canino, G, Marchfelder, A

“…Although the enzyme tRNase Z has only recently been isolated, a plethora of data has already been acquired concerning the enzyme. tRNase Z is the endonuclease…”
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This is the end: processing, editing and repair at the tRNA 3'-terminus by Schürer, H, Schiffer, S, Marchfelder, A, Mörl, M

“…The generation of a mature tRNA 3'-end is an important step in the processing pathways leading to functional tRNA molecules. While 5'-end processing by RNase P…”
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Recombinant RNase Z does not recognize CCA as part of the tRNA and its cleavage efficieny is influenced by acceptor stem length by Schiffer, Steffen, Rösch, Sylvia, Marchfelder, Anita

“…One of the essential maturation steps to yield functional tRNA molecules is the removal of 3'-trailer sequences by RNase Z. After RNase Z cleavage the tRNA…”
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The Plant tRNA 3‘ Processing Enzyme Has a Broad Substrate Spectrum by Schiffer, Steffen, Helm, Mark, Théobald-Dietrich, Anne, Giegé, Richard, Marchfelder, Anita

“…To elucidate the minimal substrate for the plant nuclear tRNA 3‘ processing enzyme, we synthesized a set of tRNA variants, which were subsequently incubated…”
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RNA editing in trans-splicing intron sequences of nad2 mRNAs in Oenothera mitochondria by BINDER, S, MARCHFELDER, A, BRENNICKE, A, WISSINGER, B

“…The complete open reading frame of subunit 2 of the NADH dehydrogenase in Oenothera mitochondria is split into five exons. The first two and the last three…”
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Characterization and Partial Purification of tRNA Processing Activities from Potato Mitochondria by Marchfelder, Anita, Brennicke, Axel

“…In plant mitochondria, as in most other genetic systems, several enzymatic processing and modification steps are required to yield mature tRNAs from primary…”
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RNA editing of tRNA(Phe) and tRNA(Cys) in mitochondria of Oenothera berteriana is initiated in precursor molecules by Binder, S, Marchfelder, A, Brennicke, A

“…We have analyzed the role of RNA editing in the correction of mismatched base pairs in tRNA secondary structures in mitochondria of the flowering plant…”
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Assigning a function to a conserved group of proteins: the tRNA 3′-processing enzymes by Schiffer, Steffen, Rösch, Sylvia, Marchfelder, Anita

“…Accurate tRNA 3′ end maturation is essential for aminoacylation and thus for protein synthesis in all organisms. Here we report the first identification of…”
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Endonucleolytic processing of CCA-less tRNA precursors by RNase Z in Bacillus subtilis by Pellegrini, Olivier, Nezzar, Jamel, Marchfelder, Anita, Putzer, Harald, Condon, Ciarán

“…In contrast to Escherichia coli, where the 3′ ends of tRNAs are primarily generated by exoribonucleases, maturation of the 3′ end of tRNAs is catalysed by an…”
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The tRNase Z family of proteins: physiological functions, substrate specificity and structural properties by Vogel, Andreas, Schilling, Oliver, Späth, Bettina, Marchfelder, Anita

“…tRNase Z is the endoribonuclease that generates the mature 3'-end of tRNA molecules by removal of the 3'-trailer elements of precursor tRNAs. This enzyme has…”
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RNA editing by Brennicke, Axel, Marchfelder, Anita, Binder, Stefan

“…Abstract The term RNA editing describes those molecular processes in which the information content is altered in an RNA molecule. To date such changes have…”
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Drosophila RNase Z processes mitochondrial and nuclear pre-tRNA 3' ends in vivo by Dubrovsky, E.B, Dubrovskaya, V.A, Levinger, L, Schiffer, S, Marchfelder, A

“…Although correct tRNA 3′ ends are crucial for protein biosynthesis, generation of mature tRNA 3′ ends in eukaryotes is poorly understood and has so far only…”
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The final cut. The importance of tRNA 3'-processing by Mörl, M, Marchfelder, A

“…To generate functional tRNA molecules, precursor RNAs must undergo several processing steps. While the enzyme that generates the mature tRNA 5'-end, RNase P,…”
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Plant dicistronic tRNA-snoRNA genes: a new mode of expression of the small nucleolar RNAs processed by RNase Z by Kruszka, Katarzyna, Barneche, Fredy, Guyot, Romain, Ailhas, Jérôme, Meneau, Isabelle, Schiffer, Steffen, Marchfelder, Anita, Echeverría, Manuel

“…Small nucleolar RNAs (snoRNAs) guiding modifications of ribosomal RNAs and other RNAs display diverse modes of gene organization and expression depending on…”
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Small RNAs of the halophilic archaeon Haloferax volcanii by Soppa, Jörg, Straub, Julia, Brenneis, Mariam, Jellen-Ritter, Angelika, Heyer, Ruth, Fischer, Susan, Granzow, Michaela, Voss, Björn, Hess, Wolfgang R, Tjaden, Brian, Marchfelder, Anita

“…In recent years, sRNAs (small non-coding RNAs) have been found to be abundant in eukaryotes and bacteria and have been recognized as a novel class of gene…”
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Analysis of the Functional Modules of the tRNA 3′ Endonuclease (tRNase Z) by Späth, Bettina, Kirchner, Silvia, Vogel, Andreas, Schubert, Sylvia, Meinlschmidt, Petra, Aymanns, Simone, Nezzar, Jamel, Marchfelder, Anita

“…tRNA 3′ processing is one of the essential steps during tRNA maturation. The tRNA 3′-processing endonuclease tRNase Z was only recently isolated, and its…”
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Exosite Modules Guide Substrate Recognition in the ZiPD/ElaC Protein Family by Schilling, Oliver, Späth, Bettina, Kostelecky, Brenda, Marchfelder, Anita, Meyer-Klaucke, Wolfram, Vogel, Andreas

“…Escherichia coli ZiPD is the best characterized protein encoded by the elaC gene family and is a model for the 3′-pre-tRNA processing endoribonucleases (tRNase…”
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tRNA 3′ End Maturation in Archaea has Eukaryotic Features: the RNase Z from Haloferax volcanii by Schierling, Karina, Rösch, Sylvia, Rupprecht, Renate, Schiffer, Steffen, Marchfelder, Anita

“…Here, we report the first characterization and partial purification of an archaeal tRNA 3′ processing activity, the RNase Z from Haloferax volcanii. The…”
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Zinc- and iron-dependent cytosolic metallo-beta-lactamase domain proteins exhibit similar zinc-binding affinities, independent of an atypical glutamate at the metal-binding site by Schilling, Oliver, Vogel, Andreas, Kostelecky, Brenda, Natal da Luz, Hugo, Spemann, Daniel, Späth, Bettina, Marchfelder, Anita, Tröger, Wolfgang, Meyer-Klaucke, Wolfram

“…ZiPD (zinc phosphodiesterase; synonyms are ElaC, ecoZ, RNaseZ and 3' tRNase) and the iron-dependent redox enzyme FlRd (flavorubredoxin) from Escherichia coli…”
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5' end maturation and RNA editing have to precede tRNA 3' processing in plant mitochondria by Kunzmann, A, Brennicke, A, Marchfelder, A

“…We report the characterization and partial purification of potato mitochondrial RNase Z, an endonuclease that generates mature tRNA 3' ends. The enzyme…”
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