Search Results - "Marchesin, Valentina"
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Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell Invasion
Published in Annual review of cell and developmental biology (06-10-2016)“…Metastasis is responsible for most cancer-associated deaths. Accumulating evidence based on 3D migration models has revealed a diversity of invasive migratory…”
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ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion
Published in The Journal of cell biology (26-10-2015)“…Invasion of cancer cells into collagen-rich extracellular matrix requires membrane-tethered membrane type 1-matrix metalloproteinase (MT1-MMP) as the key…”
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ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factor
Published in PloS one (23-03-2015)“…Coordination between actin cytoskeleton assembly and localized polarization of intracellular trafficking routes is crucial for cancer cell migration. ARF6 has…”
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Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A
Published in Cell reports (Cambridge) (24-12-2019)“…HNF4A is a nuclear hormone receptor that binds DNA as an obligate homodimer. While all known human heterozygous mutations are associated with the…”
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Family Functioning as a Constituent Aspect of a Child's Chronic Illness
Published in Journal of pediatric nursing (01-11-2015)“…This study explored how family functioning may contribute to trace a child's illness trajectory. We conducted semi-structured interviews with 33 parents of…”
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Recessive and Dominant De Novo ITPR1 Mutations Cause Gillespie Syndrome
Published in American journal of human genetics (05-05-2016)“…Gillespie syndrome (GS) is a rare variant form of aniridia characterized by non-progressive cerebellar ataxia, intellectual disability, and iris hypoplasia…”
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A uniquely efficacious type of CFTR corrector with complementary mode of action
Published in Science advances (01-03-2024)“…Three distinct pharmacological corrector types (I, II, III) with different binding sites and additive behavior only partially rescue the F508del-cystic…”
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ARF6–JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion
Published in The Journal of experimental medicine (16-11-2015)Get full text
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