Search Results - "Marchand Adam, Sylvain"
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Determinants of survival after lung transplantation in telomerase‐related gene mutation carriers: A retrospective cohort
Published in American journal of transplantation (01-04-2022)“…Carriers of germline telomerase‐related gene (TRG) mutations can show poor prognosis, with an increase in common hematological complications after lung…”
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Inhibition of the Arp2/3 complex represses human lung myofibroblast differentiation and attenuates bleomycin‐induced pulmonary fibrosis
Published in British journal of pharmacology (01-01-2022)“…Background and Purpose The Arp2/3 multiprotein complex regulates branched polymerisation of the actin cytoskeleton and may contribute to collagen synthesis and…”
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Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study)
Published in Fundamental & clinical pharmacology (01-10-2024)“…Background Mycophenolate mofetil (MMF) has been used to treat interstitial lung disease (ILD), but mycophenolate (MPA) pharmacokinetics was not reported for…”
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Transcutaneous PCO2‐based dead space ventilation at submaximal exercise accurately discriminates healthy controls from patients with chronic obstructive pulmonary disease
Published in Clinical physiology and functional imaging (01-05-2021)“…Background Increased physiological dead space ventilation (VD/VT) at exercise reflects pulmonary gas exchange impairment and is a sensitive marker of…”
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5
Impulse oscillometry and spirometry measurements relative to personal best values at the time of acute exacerbations of cystic fibrosis in adults
Published in Clinical physiology and functional imaging (01-01-2021)“…Background Diagnosis of acute exacerbation (AE) of cystic fibrosis (CF) must be precise because both under‐ and over‐prescription of antibiotics may be…”
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Similarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults
Published in Respirology (Carlton, Vic.) (01-04-2024)“…Background and Objective Variants in surfactant genes SFTPC or ABCA3 are responsible for interstitial lung disease (ILD) in children and adults, with few…”
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Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors
Published in Cancer medicine (Malden, MA) (01-04-2019)“…A comprehensive characterization of lung adenocarcinoma (LADC) clinical features is currently missing. We prospectively evaluated Caucasian patients with…”
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Pulmonary manifestations of Sjögren's syndrome
Published in European respiratory review (01-06-2016)“…In 9-20% of cases, Sjögren's syndrome is associated with various respiratory symptoms. The most typical manifestations are chronic interstitial lung disease…”
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Physiology of the lung in idiopathic pulmonary fibrosis
Published in European respiratory review (31-03-2018)“…The clinical expression of idiopathic pulmonary fibrosis (IPF) is directly related to multiple alterations in lung function. These alterations derive from a…”
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Extracellular ATP Is a Danger Signal Activating P2X7 Receptor in Lung Inflammation and Fibrosis
Published in American journal of respiratory and critical care medicine (15-09-2010)“…Pulmonary fibrosis is a devastating as yet untreatable disease. We previously investigated the endogenous mediators released on lung injury and showed that…”
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Comorbidities of COPD
Published in European respiratory review (01-12-2013)“…By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality. Extrapulmonary comorbidities influence the prognosis of patients…”
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Women and COPD: do we need more evidence?
Published in European respiratory review (31-03-2019)“…The increasingly female face of chronic obstructive pulmonary disease (COPD) prevalence among women has equalled that of men since 2008, due in part to…”
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Transcutaneous PCO 2 -based dead space ventilation at submaximal exercise accurately discriminates healthy controls from patients with chronic obstructive pulmonary disease
Published in Clinical physiology and functional imaging (01-05-2021)“…Increased physiological dead space ventilation (V /V ) at exercise reflects pulmonary gas exchange impairment and is a sensitive marker of cardio-respiratory…”
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14
Clinical performance of four immunoassays for antibodies to SARS-CoV-2, including a prospective analysis for the diagnosis of COVID-19 in a real-life routine care setting
Published in Journal of clinical virology (01-11-2020)“…•The sensitivity of evaluated SARS-CoV-2 immunoassays ranged from 95.6% to 97.8%.•The specificity was 92.1% for Euroimmun IgG and ≥ 98.9% for Abbott IgG,…”
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15
Tracheal involvement in ulcerative colitis: clinical presentation and potential interest of 2-deoxy-2[18F]fluoro-d-glucose positron emission tomography (18F-FDG PET) for the management
Published in Annals of nuclear medicine (01-12-2012)“…Ulcerative colitis (UC) is an inflammatory bowel disease that can on rare occasions affect the respiratory tract. We report the case of a 32-year-old woman…”
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16
B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis
Published in Journal of autoimmunity (01-01-2015)“…Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive devastating, yet untreatable fibrotic disease of unknown origin. We investigated the contribution…”
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Transcriptome of Cultured Lung Fibroblasts in Idiopathic Pulmonary Fibrosis: Meta-Analysis of Publically Available Microarray Datasets Reveals Repression of Inflammation and Immunity Pathways
Published in International journal of molecular sciences (13-12-2016)“…Heritable profibrotic differentiation of lung fibroblasts is a key mechanism of idiopathic pulmonary fibrosis (IPF). Its mechanisms are yet to be fully…”
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Proteomic biomarkers for survival in systemic sclerosis-associated pulmonary hypertension
Published in Respiratory research (07-11-2023)“…Background Interstitial lung disease (ILD) and pulmonary hypertension (PH) represent the major causes of mortality in systemic sclerosis (SSc). Patients with…”
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Chronic interstitial lung disease associated with systemic lupus erythematosus: A multicentric study of 89 cases
Published in Respirology (Carlton, Vic.) (01-08-2024)“…Background and Objective Chronic interstitial lung disease (ILD) occurs rarely with systemic lupus erythematosus (SLE) as compared with other connective tissue…”
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Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases
Published in The Journal of biological chemistry (15-04-2016)“…The cysteine protease cathepsin C (CatC) activates granule-associated proinflammatory serine proteases in hematopoietic precursor cells. Its early inhibition…”
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