Search Results - "Marchand, S"

Concept attribution: Explaining CNN decisions to physicians by M, Graziani, V, Andrearczyk, S, Marchand-Maillet, H, Müller

“…Deep learning explainability is often reached by gradient-based approaches that attribute the network output to perturbations of the input pixels. However, the…”
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Recommendations on practice of conditioned pain modulation (CPM) testing by Yarnitsky, D., Bouhassira, D., Drewes, A.M., Fillingim, R.B., Granot, M., Hansson, P., Landau, R., Marchand, S., Matre, D., Nilsen, K.B., Stubhaug, A., Treede, R.D., Wilder-Smith, O.H.G.

“…Protocols for testing conditioned pain modulation (CPM) vary between different labs/clinics. In order to promote research and clinical application of this…”
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New SMOS Sea Surface Salinity with reduced systematic errors and improved variability by Boutin, J., Vergely, J.L., Marchand, S., D'Amico, F., Hasson, A., Kolodziejczyk, N., Reul, N., Reverdin, G., Vialard, J.

“…Salinity observing satellites have the potential to monitor river fresh-water plumes mesoscale spatio-temporal variations better than any other observing…”
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High-throughput sequencing for infectious disease diagnoses: Example of shotgun metagenomics in central nervous system infections by Marchand, S, Rodriguez, C, Woerther, P-L

“…The advent of high-throughput sequencing in clinical microbiology is opening the way to new diagnostic and prognostic approaches in infectious diseases…”
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Colistin pharmacokinetics: the fog is lifting by Couet, W., Grégoire, N., Marchand, S., Mimoz, O.

“…Colistin is a re-emerging old antibiotic that is used to treat multidrug-resistant infections in critically ill patients. It corresponds to a mixture of at…”
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Pharmacokinetics of Colistin and Colistimethate Sodium After a Single 80-mg Intravenous Dose of CMS in Young Healthy Volunteers by Couet, W, Grégoire, N, Gobin, P, Saulnier, PJ, Frasca, D, Marchand, S, Mimoz, O

“…Colistin pharmacokinetics (PK) was investigated in young healthy volunteers after a 1‐h infusion of 80 mg (1 million international units (MIU)) of the prodrug…”
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The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections by Tängdén, T., Ramos Martín, V., Felton, T. W., Nielsen, E. I., Marchand, S., Brüggemann, R. J., Bulitta, J. B., Bassetti, M., Theuretzbacher, U., Tsuji, B. T., Wareham, D. W., Friberg, L. E., De Waele, J. J., Tam, V. H., Roberts, Jason A.

“…Critically ill patients with severe infections are at high risk of suboptimal antimicrobial dosing. The pharmacokinetics (PK) and pharmacodynamics (PD) of…”
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Modelled Target Attainment after Temocillin Treatment in Severe Pneumonia: Systemic and Epithelial Lining Fluid Pharmacokinetics of Continuous versus Intermittent Infusions by Layios, N, Visée, C, Mistretta, V, Denooz, R, Maes, N, Descy, J, Frippiat, F, Marchand, S, Grégoire, N

“…The objective of this article is to describe the population pharmacokinetics (PK) of temocillin administered via continuous infusion (CI) versus intermittent…”
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Lung function parameters in omalizumab responder patients: An interesting tool? by Paganin, F., Mangiapan, G., Proust, A., Prudhomme, A., Attia, J., Marchand‐Adam, S., Pellet, F., Milhe, F., Melloni, B., Bernady, A., Raspaud, C., Nocent, C., Berger, P., Guilleminault, L.

“…Background Omalizumab, an anti‐IgE antibody, is used to treat patients with severe allergic asthma. The evolution of lung function parameters over time and the…”
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New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale by Grégoire, N, Mimoz, O, Mégarbane, B, Comets, E, Chatelier, D, Lasocki, S, Gauzit, R, Balayn, D, Gobin, P, Marchand, S, Couet, W

“…Colistin is an old antibiotic that has recently gained a considerable renewal of interest as the last-line defense therapy against multidrug-resistant…”
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Targeting lung macrophages for fungal and parasitic pulmonary infections with innovative amphotericin B dry powder inhalers by de Pablo, E., O'Connell, P., Fernández-García, R., Marchand, S., Chauzy, A., Tewes, F., Dea-Ayuela, M.A., Kumar, D., Bolás, F., Ballesteros, M.P., Torrado, J.J., Healy, A.M., Serrano, D.R.

“…[Display omitted] The incidence of fungal pulmonary infections is known to be on the increase, and yet there is an alarming gap in terms of marketed antifungal…”
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Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition by Julien, Nancy, Goffaux, Philippe, Arsenault, Pierre, Marchand, Serge

“…A deficit of endogenous pain inhibitory systems has been suggested to contribute to some chronic pain conditions, one of them being fibromyalgia. The aim of…”
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Co-purification of arrestin like proteins with alpha-enolase from bovine myocardial tissues and the possible role in heart diseases as an autoantigen by Mirshahi, M., Le Marchand, S.

“…Previously, we reported that visual arrestin co-purified with glycolytic enzymes. The aim of this study was to analyze the co-purification of arrestin like…”
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Recommendations on terminology and practice of psychophysical DNIC testing by Yarnitsky, David, Arendt-Nielsen, Lars, Bouhassira, Didier, Edwards, Robert R, Fillingim, Roger B, Granot, Michal, Hansson, Per, Lautenbacher, Stefan, Marchand, Serge, Wilder-Smith, Oliver

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Sequential Time-Kill, a Simple Experimental Trick To Discriminate between Pharmacokinetics/Pharmacodynamics Models with Distinct Heterogeneous Subpopulations versus Homogenous Population with Adaptive Resistance by Chauzy, A, Ih, H, Jacobs, M, Marchand, S, Grégoire, N, Couet, W, Buyck, J M

“…Experiments were conducted with polymyxin B and two isogenic strains (the wild type, KP_WT, and its transconjugant carrying the mobile colistin resistance…”
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Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii by Aranzana-Climent, V., Buyck, J.M., Smani, Y., Pachón-Diaz, J., Marchand, S., Couet, W., Grégoire, N.

“…To expand on previous reports of synergy between polymyxin B (PMB) and minocycline (MIN) against Acinetobacter baumannii; and to gain insight into the…”
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Population Pharmacokinetics of Colistin Methanesulfonate and Colistin in Critically Ill Patients with Acute Renal Failure Requiring Intermittent Hemodialysis by Jacobs, M, Grégoire, N, Mégarbane, B, Gobin, P, Balayn, D, Marchand, S, Mimoz, O, Couet, W

“…Colistin is increasingly used as a last option for the treatment of severe infections due to Gram-negative bacteria in critically ill patients requiring…”
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Concentration‐dependent effect of amoxicillin against clinical strains of Helicobacter pylori by Kaouah, Z., Buyck, J., Pichon, M., Burucoa, C., Prouvensier, L., Moreau, J., Marchand, S., Gregoire, N., Cremniter, J.

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Pain Modulation Mechanisms in ASD Adults by Dubois, A., Boudjarane, M., Le Fur-Bonnabesse, A., Dion, A., L’heveder, G., Quinio, B., Walter, M., Marchand, S., Bodéré, C.

“…We tested endogenous pain modulation mechanisms in adults with autism spectrum disorders (ASD). Nineteen ASD adults without intellectual disabilities were…”
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Patient preferences for physical therapy programs after a lower extremity fracture: a discrete choice experiment by McKibben, Natasha S, Marchand, Lucas S, Demyanovich, Haley K, Healey, Kathleen M, Zingas, Nicolas, O'Connor, Katherine, Slobogean, Gerard P, O'Toole, Robert V, O'Hara, Nathan N

“…ObjectiveTo quantify patients’ preferences for physical therapy programmes after a lower extremity fracture and determine patient factors associated with…”
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