Search Results - "Marchand, Jorge A"

A swapped genetic code prevents viral infections and gene transfer by Nyerges, Akos, Vinke, Svenja, Flynn, Regan, Owen, Siân V., Rand, Eleanor A., Budnik, Bogdan, Keen, Eric, Narasimhan, Kamesh, Marchand, Jorge A., Baas-Thomas, Maximilien, Liu, Min, Chen, Kangming, Chiappino-Pepe, Anush, Hu, Fangxiang, Baym, Michael, Church, George M.

“…Engineering the genetic code of an organism has been proposed to provide a firewall from natural ecosystems by preventing viral infections and gene transfer 1…”
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Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA by Kawabe, Hinako, Thomas, Christopher A., Hoshika, Shuichi, Kim, Myong-Jung, Kim, Myong-Sang, Miessner, Logan, Kaplan, Nicholas, Craig, Jonathan M., Gundlach, Jens H., Laszlo, Andrew H., Benner, Steven A., Marchand, Jorge A.

“…The 4-letter DNA alphabet (A, T, G, C) as found in Nature is an elegant, yet non-exhaustive solution to the problem of storage, transfer, and evolution of…”
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A family of radical halogenases for the engineering of amino-acid-based products by Neugebauer, Monica E., Sumida, Kiera H., Pelton, Jeffrey G., McMurry, Jonathan L., Marchand, Jorge A., Chang, Michelle C. Y.

“…The integration of synthetic and biological catalysis enables new approaches to the synthesis of small molecules by combining the high selectivity of enzymes…”
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Reaction pathway engineering converts a radical hydroxylase into a halogenase by Neugebauer, Monica E., Kissman, Elijah N., Marchand, Jorge A., Pelton, Jeffrey G., Sambold, Nicholas A., Millar, Douglas C., Chang, Michelle C. Y.

“…Fe II /α-ketoglutarate (Fe II /αKG)-dependent enzymes offer a promising biocatalytic platform for halogenation chemistry owing to their ability to…”
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Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases by Kissman, Elijah N, Neugebauer, Monica E, Sumida, Kiera H, Swenson, Cameron V, Sambold, Nicholas A, Marchand, Jorge A, Millar, Douglas C, Chang, Michelle C Y

“…Biocatalytic C-H activation has the potential to merge enzymatic and synthetic strategies for bond formation. Fe /αKG-dependent halogenases are particularly…”
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TBDB: a database of structurally annotated T-box riboswitch:tRNA pairs by Marchand, Jorge A, Pierson Smela, Merrick D, Jordan, Thomas H H, Narasimhan, Kamesh, Church, George M

“…Abstract T-box riboswitches constitute a large family of tRNA-binding leader sequences that play a central role in gene regulation in many gram-positive…”
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TBDB: a database of structurally annotated T-box riboswitch:tRNA pairs by Marchand, Jorge A., Pierson Smela, Merrick D., Jordan, Thomas H. H., Narasimhan, Kamesh, Church, George M.

“…Abstract T-box riboswitches constitute a large family of tRNA-binding leader sequences that play a central role in gene regulation in many gram-positive…”
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Biosynthesis and Translational Control of Terminal-Alkyne Amino Acids by Benmaman, Jorge A. Marchand

“…Living systems are remarkably efficient in their ability to build complex molecular function, using a relatively small set of chemical functional groups to…”
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