Search Results - "Marchal, Juan A"

Phenformin as an Anticancer Agent: Challenges and Prospects by García Rubiño, Mª Eugenia, Carrillo, Esmeralda, Ruiz Alcalá, Gloria, Domínguez-Martín, Alicia, A Marchal, Juan, Boulaiz, Houria

“…Currently, there is increasing evidence linking diabetes mellitus (especially type 2 diabetes mellitus) with carcinogenesis through various biological…”
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Recent Progress in Gene Therapy for Ovarian Cancer by Áyen, Ángela, Jiménez Martínez, Yaiza, Marchal, Juan A, Boulaiz, Houria

“…Ovarian cancer is the most lethal gynecological malignancy in developed countries. This is due to the lack of specific symptoms that hinder early diagnosis and…”
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Biogeneration of silver nanoparticles from Cuphea procumbens for biomedical and environmental applications by González-Pedroza, María G., Benítez, Andrea Regina Tapia, Navarro-Marchal, Saúl A., Martínez-Martínez, Eduardo, Marchal, Juan A., Boulaiz, Houria, Morales-Luckie, Raúl A.

“…Nanotechnology is one of the most important and relevant disciplines today due to the specific electrical, optical, magnetic, chemical, mechanical and…”
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liqDB: a small-RNAseq knowledge discovery database for liquid biopsy studies by Aparicio-Puerta, Ernesto, Jáspez, David, Lebrón, Ricardo, Koppers-Lalic, Danijela, Marchal, Juan A, Hackenberg, Michael

“…Abstract MiRNAs are important regulators of gene expression and are frequently deregulated under pathologic conditions. They are highly stable in bodily fluids…”
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Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression by Picon-Ruiz, Manuel, Pan, Chendong, Drews-Elger, Katherine, Jang, Kibeom, Besser, Alexandra H, Zhao, Dekuang, Morata-Tarifa, Cynthia, Kim, Minsoon, Ince, Tan A, Azzam, Diana J, Wander, Seth A, Wang, Bin, Ergonul, Burcu, Datar, Ram H, Cote, Richard J, Howard, Guy A, El-Ashry, Dorraya, Torné-Poyatos, Pablo, Marchal, Juan A, Slingerland, Joyce M

“…Consequences of the obesity epidemic on cancer morbidity and mortality are not fully appreciated. Obesity is a risk factor for many cancers, but the mechanisms…”
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Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells by Morata-Tarifa, Cynthia, Jiménez, Gema, García, María A., Entrena, José M., Griñán-Lisón, Carmen, Aguilera, Margarita, Picon-Ruiz, Manuel, Marchal, Juan A.

“…Cancer stem cells are responsible for tumor progression, metastasis, therapy resistance and cancer recurrence, doing their identification and isolation of…”
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Large-Scale Production of Lentiviral Vectors: Current Perspectives and Challenges by Martínez-Molina, Eduardo, Chocarro-Wrona, Carlos, Martínez-Moreno, Daniel, Marchal, Juan A., Boulaiz, Houria

“…Lentiviral vectors (LVs) have gained value over recent years as gene carriers in gene therapy. These viral vectors are safer than what was previously being…”
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Thermo-Sensitive Nanomaterials: Recent Advance in Synthesis and Biomedical Applications by Sánchez-Moreno, Paola, de Vicente, Juan, Nardecchia, Stefania, Marchal, Juan A, Boulaiz, Houria

“…Progress in nanotechnology has enabled us to open many new fronts in biomedical research by exploiting the peculiar properties of materials at the nanoscale…”
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Clinical Trials of Thermosensitive Nanomaterials: An Overview by Nardecchia, Stefania, Sánchez-Moreno, Paola, Vicente, Juan de, Marchal, Juan A, Boulaiz, Houria

“…Currently, we are facing increasing demand to develop efficient systems for the detection and treatment of diseases that can realistically improve distinct…”
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Immune cell impact of three differently coated lipid nanocapsules: pluronic, chitosan and polyethylene glycol by Farace, Cristiano, Sánchez-Moreno, Paola, Orecchioni, Marco, Manetti, Roberto, Sgarrella, Francesco, Asara, Yolande, Peula-García, José M., Marchal, Juan A., Madeddu, Roberto, Delogu, Lucia G.

“…Lipid nanocapsules (NCs) represent promising tools in clinical practice for diagnosis and therapy applications. However, the NC appropriate functionalization…”
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Intra-Articular Injections of Platelet-Rich Plasma versus Hyaluronic Acid in the Treatment of Osteoarthritic Knee Pain: A Randomized Clinical Trial in the Context of the Spanish National Health Care System by Montañez-Heredia, Elvira, Irízar, Sofia, Huertas, Pedro J, Otero, Esperanza, Del Valle, Marta, Prat, Isidro, Díaz-Gallardo, Macarena S, Perán, Macarena, Marchal, Juan A, Hernandez-Lamas, María Del Carmen

“…Intra-articular injection of platelet-rich plasma (PRP) has been established as a suitable treatment for knee osteoarthritis. Here, we present a double-blind…”
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The impact of PKR activation: from neurodegeneration to cancer by Marchal, Juan A., Lopez, Gabriel J., Peran, Macarena, Comino, Ana, Delgado, Juan R., García‐García, Javier A., Conde, Veronica, Aranda, Fernando M., Rivas, Carmen, Esteban, Mariano, Garcia, Maria A.

“…ABSTRACT An inverse association between cancer and neurodegeneration is plausible because these biological processes share several genes and signaling…”
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Metabolomic profile of cancer stem cell‐derived exosomes from patients with malignant melanoma by Palacios‐Ferrer, José Luis, García‐Ortega, María Belén, Gallardo‐Gómez, María, García, María Ángel, Díaz, Caridad, Boulaiz, Houria, Valdivia, Javier, Jurado, José Miguel, Almazan‐Fernandez, Francisco M., Arias‐Santiago, Salvador, Amezcua, Víctor, Peinado, Héctor, Vicente, Francisca, Pérez del Palacio, José, Marchal, Juan A.

“…Malignant melanoma (MM) is the most aggressive form of skin cancer, with increasing incidence worldwide. To date, there are no suitable clinical diagnostic,…”
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Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling by Ramos, Maria C., Crespo-Sueiro, Gloria, de Pedro, Nuria, Griñán-Lisón, Carmen, Díaz, Caridad, Pérez-Victoria, Ignacio, González-Menéndez, Víctor, Castillo, Francisco, Pérez del Palacio, Jose, Tormo, Jose R., Choquesillo-Lazarte, Duane, Marchal, Juan A., Vicente, Francisca, Fernández-Godino, Rosario, Genilloud, Olga, Reyes, Fernando

“…Pancreatic cancer (PC) shows a high fatality rate that can only be faced with a combination of surgery and chemotherapy or palliative treatment in the case of…”
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Nanomedicine: application areas and development prospects by Boulaiz, Houria, Alvarez, Pablo J, Ramirez, Alberto, Marchal, Juan A, Prados, Jose, Rodríguez-Serrano, Fernando, Perán, Macarena, Melguizo, Consolación, Aranega, Antonia

“…Nanotechnology, along with related concepts such as nanomaterials, nanostructures and nanoparticles, has become a priority area for scientific research and…”
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Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells by Calahorra, Jesús, Blaya-Cánovas, José L., Castellini-Pérez, Olivia, Aparicio-Puerta, Ernesto, Cives-Losada, Candela, Marin, Jose J.G., Rementeria, Markel, Cara, Francisca E., López-Tejada, Araceli, Griñán-Lisón, Carmen, Aulicino, Francesco, Berger, Imre, Marchal, Juan A., Delgado-Almenta, Violeta, Granados-Principal, Sergio

“…Triple-negative breast cancer (TNBC) is characterised by its aggressiveness and resistance to chemotherapy, demanding the development of effective strategies…”
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Antioxidants for the Treatment of Breast Cancer: Are We There Yet? by Griñan-Lison, Carmen, Blaya-Cánovas, Jose L, López-Tejada, Araceli, Ávalos-Moreno, Marta, Navarro-Ocón, Alba, Cara, Francisca E, González-González, Adrián, Lorente, Jose A, Marchal, Juan A, Granados-Principal, Sergio

“…Breast cancer is the most frequent cancer and the leading cause of cancer death in women. Oxidative stress and the generation of reactive oxygen species (ROS)…”
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Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders by Roman, Sabiniano, Agil, Ahmad, Peran, Macarena, Alvaro-Galue, Eduardo, Ruiz-Ojeda, Francisco J, Fernández-Vázquez, Gumersindo, Marchal, Juan A

“…In humans, 2 functionally different types of adipose tissue coexist: white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is involved in energy…”
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Functionalized nanostructures with application in regenerative medicine by Perán, Macarena, García, María A, López-Ruiz, Elena, Bustamante, Milán, Jiménez, Gema, Madeddu, Roberto, Marchal, Juan A

“…In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in…”
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Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines by Cruz-López, Olga, Ner, Matilde, Nerín-Fonz, Francho, Jiménez-Martínez, Yaiza, Araripe, David, Marchal, Juan A., Boulaiz, Houria, Gutiérrez-de-Terán, Hugo, Campos, Joaquín M., Conejo-García, Ana

“…A series of 11 new substituted 1,5-dihydro-4,1-benzoxazepine derivatives was synthesised to study the influence of the methyl group in the 1-(benzenesulphonyl)…”
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