Search Results - "Marcelo, Aileen"

The potential role of perlecan domain V as novel therapy in vascular dementia by Marcelo, Aileen, Bix, Gregory

“…Vascular dementia (VaD) is the second most common cause of dementia and leads to a decline in cognitive thinking via conditions that lead to blockage or…”
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Investigating the role of perlecan domain V in post-ischemic cerebral angiogenesis by Marcelo, Aileen, Bix, Gregory

“…Cerebral angiogenesis is an important process for physiological events such as brain development, but it also occurs in pathological conditions such as stroke…”
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Perlecan Domain-V Enhances Neurogenic Brain Repair After Stroke in Mice by Trout, Amanda L., Kahle, Michael P., Roberts, Jill M., Marcelo, Aileen, de Hoog, Leon, Boychuk, Jeffery A., Grupke, Stephen L., Berretta, Antonio, Gowing, Emma K., Boychuk, Carie R., Gorman, Amanda A., Edwards, Danielle N., Rutkai, Ibolya, Biose, Ifechukwude J., Ishibashi-Ueda, Hatsue, Ihara, Masafumi, Smith, Bret N., Clarkson, Andrew N., Bix, Gregory J.

“…The extracellular matrix fragment perlecan domain V is neuroprotective and functionally restorative following experimental stroke. As neurogenesis is an…”
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The α7-nicotinic acetylcholine receptor and MMP-2/-9 pathway mediate the proangiogenic effect of nicotine in human retinal endothelial cells by Dom, Aaron M, Buckley, Adam W, Brown, Kathleen C, Egleton, Richard D, Marcelo, Aileen J, Proper, Nancy A, Weller, Donald E, Shah, Yashoni H, Lau, Jamie K, Dasgupta, Piyali

“…Nicotine, the active component of cigarette smoke, has been found to stimulate angiogenesis in several experimental systems. In this study, the Matrigel duplex…”
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MG624, an α7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway by Brown, Kathleen C., Lau, Jamie K., Dom, Aaron M., Witte, Theodore R., Luo, Haitao, Crabtree, Clayton M., Shah, Yashoni H., Shiflett, Brandon S., Marcelo, Aileen J., Proper, Nancy A., Hardman, W. Elaine, Egleton, Richard D., Chen, Yi Charlie, Mangiarua, Elsa I., Dasgupta, Piyali

“…Small cell lung cancer (SCLC) demonstrates a strong etiological association with smoking. Although cigarette smoke is a mixture of about 4,000 compounds,…”
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Non‐coding RNA Editing Involved in Adipose Dysfunction during Aging by Seidler, Abbagael, Marcelo, Aileen, Page, Jamika, Santanam, Nalini

“…Abstract only Adipose tissue is one of the key endocrine organs that maintain lipid and glucose homeostasis. Adipose dysfunction increases upon aging, and…”
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Thimerosal Induces Apoptosis in a Neuroblastoma Model via the cJun N-Terminal Kinase Pathway by Herdman, Michelle L., Marcelo, Aileen, Huang, Ying, Niles, Richard M., Dhar, Sanjit, Kiningham, Kinsley Kelley

“…The cJun N-terminal kinase (JNK)-signaling pathway is activated in response to a variety of stimuli, including environmental insults, and has been implicated…”
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Erratum to: MG624, an α7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway by Brown, Kathleen C., Lau, Jamie K., Dom, Aaron M., Witte, Theodore R., Luo, Haitao, Crabtree, Clayton M., Shah, Yashoni H., Shiflett, Brandon S., Marcelo, Aileen J., Proper, Nancy A., Hardman, W. Elaine, Egleton, Richard D., Chen, Yi Charlie, Mangiarua, Elsa I., Dasgupta, Piyali

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Erratum to: MG624, an [alpha]7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway by Brown, Kathleen C, Lau, Jamie K, Dom, Aaron M, Witte, Theodore R, Luo, Haitao, Crabtree, Clayton M, Shah, Yashoni H, Shiflett, Brandon S, Marcelo, Aileen J, Proper, Nancy A, Hardman, W Elaine, Egleton, Richard D, Chen, Yi Charlie, Mangiarua, Elsa I, Dasgupta, Piyali

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The role of vascular endothelial growth factor at the blood-brain barrier in diabetes by Marcelo, Aileen J

“…Diabetes is a risk factor for stroke and vascular dementia. Clinical studies using gadolinium-magnetic resonance imaging techniques have shown diabetic…”
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MG624, an [alpha]7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway by Brown, Kathleen C, Lau, Jamie K, Dom, Aaron M, Witte, Theodore R, Luo, Haitao, Crabtree, Clayton M, Shah, Yashoni H, Shiflett, Brandon S, Marcelo, Aileen J, Proper, Nancy A, Hardman, W Elaine, Egleton, Richard D, Chen, Yi Charlie, Mangiarua, Elsa I, Dasgupta, Piyali

“…Small cell lung cancer (SCLC) demonstrates a strong etiological association with smoking. Although cigarette smoke is a mixture of about 4,000 compounds,…”
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Abstract 163: Delayed Administration of Perlecan Doman V Significantly Increases Neurogenesis and Improves Functional Outcome after Experimental Ischemic Stroke by Marcelo-McCabe, Aileen, de Hoog, Leon, Clarkson, Andrew, Kahle, Michael, Bix, Gregory

“…Abstract only Stroke, a major cause of significant morbidity and death, has limited therapeutic options. To that end, our goal is to develop novel stroke…”
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